ISLAM, MD. ARIFUL; AKHTAR, MOST. AFIA; ISLAM KHAN, MD. RAFIQUL; HOSSAIN, MD. SAROWAR; ALAM, A. H. M. KHURSHID; IMAM IBNE WAHED, MIR; AMRAN, MD. SHAH; MOKADDESUR RAHMAN, BYTUL; AHMED, MARUF(Karachi: Faculty of Pharmacy, University of Karachi, 2009-10)
The aim of this study is to investigate the hypoglycemic effects of petroleum ether, chloroform and ethyl acetate fractions isolated from ethanolic extracts of Coccinia cordifolia and Catharanthus roseus on normal control ...
REZA HEIDARI, MAHMOUD; FOROUMADI, ALIREZA; NOROOZI, HOJAT; SAMZADEH-KERMANI, ALI; SARVAR AZIMZADEH, BEHZAD(Karachi: Faculty of Pharmacy, University of Karachi, 2009-10)
It is reported that dihydroxy chalcones have analgesic and anti-inflammatory effects. Study of the structure activity relationship (SAR) shows that benzofuran-3-one derivatives may be more effective in this respect. In ...
ANANDAN, RAMASAMY; JAYAKAR, BALASUNDARAM; KARAR, BIUSAN; BABUJI, SEEVALEN; MANAVALAN, RAJAPPAN; SENTHIL KUMAR, RAJU(Karachi: Faculty of Pharmacy, University of Karachi, 2009-10)
Hepatoprotective activity of ethanolic extract of flowers of Vitex trifolia (Verbenaceae) was studied against CCl4 induced hepatic injury in albino rats. The plant extract (EVT) at the dose of 200 mg/kg, p.o. showed a ...
E OKOKON, JUDE; A NWAFOR, PAUL(ANTIULCER AND ANTICONVULSANT ACTIVITY OF CROTON ZAMBESICUS, 2009-10)
The ethanolic root extract of Croton zambesicus was investigated for its potential to protect gastric mucosa against ulcers induced by indomethacin, ethanol and reserpine. The anticonvulsant activity of the root extract ...
In this study, the diuretic activity of powdered cherry stalk was evaluated in 13 healthy volunteers by means of their water balance. In addition to biochemical parameters, such as urinary electrolyte concentration, ...
ELDIN I. HARISA, GAMAL; M. ABO-SALEM, OSAMA; M. EL-SAYED, EL-SAYED; I. TAHA, EHAB; EL-HALAWANY5, NERMIN(2009-10)
Garlic contains many sulfhydryl compounds that act as antioxidants. However, the role of nitric oxide (NO) in inflammation is controversial. The aim of the present study is to investigate the possible protective effect of ...
SWARAN B, SANGAME; KRISHNAN BR, BALA; DESHRAJ, CHUMBHALE; B, JAYAKAR(Karachi: Faculty of Pharmacy, University of Karachi, 2009-10-04)
The free radical scavenging potential of roots of Thespesia lampas Dalz and Gibs was studied by different antioxidant models. Free radicals are implicated for more than 80 diseases including Diabetes mellitus, arthritis, ...
A. KHAN, SEHER(Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2009-07-20)
Colon cancer is one of the major causes of cancer-related death in the Western world. Although cytotoxic
chemotherapeutic agents are available to treat the disease, these agents become ineffective as the disease
advances ...
The objective of this study was to evaluate the effect of drug loading and the effect of excipients on the release pattern of tamsulosin tydrochloride from in situ PLGA implants formed in vitro in gelatin gel. This system ...
Production of antimicrobial compounds seems to be a general phenomenon for most bacteria. The prevalence of antimicrobial resistance among key microbial pathogens is increasing at an alarming rate worldwide. Current
solutions ...
Several plants are used in folk medicine to treat infections. Carpolobia lutea, G.Don (Polygalaceae) is a
medicinal plant commonly used by herbalists in Southern Nigeria against dental and genitourinary infections.
The ...
KHALID KHAN, MUHAMMAD; FARID KHAN, MUHAMMAD; KHAN, HAROON; MUSTAFA, G(Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2009-07-17)
Bioavailabilities of seven tablets of ciprofloxacin were determined. The co-rrelation between in-vivo
bioavailability parameters and in-vitro dissolution rates were studied. Ciprofloxacin concentration from the
blood was ...
RIAZ, AZRA; ALAM KHAN, RAFEEQ; PARVEEN AHMED, SHAHIDA(Karachi: Faculty of Pharmacy, University of Karachi, 2009-10-22)
Effect of evening primrose oil (EPO) was assessed on coagulation parameters following 30 and 60 days administration of 90, 180 and 360 µl/kg oil to healthy rabbits of either sex. There was significant increase in all assays ...
B. MESHRAM, DHANANJAY; B. BAGADE, SHASHIKANT; R. TAJNE, MADHUKAR(Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2009-07-16)
A new, simple, precise, rapid and selective high-performance thin-layer chromatographic (HPTLC) method for
the simultaneous quantification of Metronidazole (MTZ) and Miconazole nitrate (MCZ) in gel has been
developed. ...
Four commonly used spices plants in Iran were evaluated for cytotoxicity effect using Brine Shrimp Lethality
(BSL) assay. Essential oils and various extracts of Heracleum persicum, Nigella arvensis, Cinnamomum
zeylanicum ...
SERARSLAN, YURDAL; BAL, RAMAZAN; ENES ALTUĞ, MUHAMMED; KONTAŞ, TÜNAY; MURAT MELEK, İSMET(Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2009-07-14)
Effects of caffeic acid phenethyl ester (CAPE) on the serum S-100B levels were studied as an index for brain
damage after permanent middle cerebral artery (MCA) occlusion in rabbits. Twenty rabbits were divided into
four ...
Effects of Hyoscyamus niger L on central nervous system have been known for many years. The effects of
methanolic extract of H. niger L. on seizures induced by picrotoxin was studied in mice in this investigation. In
this ...
MILLAT IBN RAZZAK, MD. SHAIKHUL; KHAN, FERDOUS; HOSSAIN, MASUMA; RAHMAN KHAN, MD. ZIAUR; ABUL KALAM AZAD, MOHAMMAD; REZA, MD. SELIM(Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2009-07-12)
The purpose of the present study was to investigate the effect of channeling agent on the release profile of
theophylline from Kollidon SR based matrix systems. Matrix tablets of theophylline using Kollidon SR which ...
Two Simple, rapid, accurate and economical ‘UV Spectrophotometry’ and ‘First Order Derivative’ methods
have been developed for determination of levofloxacin hemihydrate in bulk and tablets. In (10% v/v)
acetonitrile, the ...
It is a comparative study of salbutamol sulpahte-ethylcellulose microcapsules prepared by three different
microencapsulation techniques i.e. coacervation thermal change, solvent evaporation and coacervation nonsolvent ...