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  • ANTI-BACTERIAL ACTIVITY OF ETHANOLIC EXTRACT OF INDONEESIELLA ECHIOIDES (L) NEES. EVALUATED BY THE FILTER PAPER DISC METHOD 
    LATIEF QADRIE, ZULFKAR; JACOB, BEENA; ANANDAN, R; RAJKAPOOR, B; RAHAMATH ULLA, MOHAMMED (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2009-07-01)
    The study was carried out to investigate the antibacterial activity of the ethanolic extracts of Indoneesiella echioides (L) Nees. was evaluated by the filter paper disc method. This method is based on the diffusion of ...
  • ANTIBACTERIAL ACTIVITY IN VITRO OF THYMUS CAPITATUS FROM JORDAN 
    N QARALLEH, HAITHAM; M ABBOUD, MUAYAD; M KHLEIFAT, KHALED; A TARAWNEH, KHALED; Y ALTHUNIBAT, OSAMA (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2009-10-01)
    This study was carried out to evaluate the antibacterial activity of aqueous and organic extracts of Thymus capitatus L. (Lamiaceae) leaves and stems. Dried ground powder leaves and stems were extracted with water (aqueous ...
  • ANTIBIOTIC PRODUCTION BY THERMOPHILIC BACILLUS SPECIE SAT-4 
    MUHAMMAD, SYED AUN; AHMAD, SAFIA; HAMEED, ABDUL (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2009-07-19)
    Production of antimicrobial compounds seems to be a general phenomenon for most bacteria. The prevalence of antimicrobial resistance among key microbial pathogens is increasing at an alarming rate worldwide. Current solutions ...
  • ANTIMICROBIAL ACTIVITIES OF THE VOLATILE OILS OF OCIMUM BACILICUM L. AND OCIMUM GRATISSIMUM L. (LAMIACEAE) AGAINST SOME AEROBIC DENTAL ISOLATES 
    AHONKHAI I, AHONKHAI; AYINDE BA, AYINDE; EDOGUN O, EDOGUN; UHUWMANGHO MU, UHUWMANGHO (Karachi: Faculty of Pharmacy, University of Karachi, 2009-10)
    Essential or volatile oils of plants have been variously reported to have many medicinal applications. Their probable uses against oral microbes have received little attention. Oral swabs obtained from eighteen dental ...
  • ANTINOCICEPTIVE AND ANTI-PYRETIC ACTIVITY OF BENINCASA HISPIDA (THUNB.) COGN. IN WISTAR ALBINO RATS 
    LATIEF QADRIE, ZULFKAR; TAYEB HAWISA, NAJAT; WAJID ALI KHAN, MOHD.; SAMUEL, MOSES; ANANDAN, R (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2009-07-10)
    The seeds of Benincasa hispida (Thunb) COGN. (Family: Cucurbitaceae) was extracted with ethanol and was used to study acute toxicity, antinociceptive and anti-pyretic effects. Brewer’s yeast (15%) was used to induce pyrexia ...
  • ANTIOXIDANT ACTIVITY, PHENOL AND FLAVONOID CONTENTS OF 13 CITRUS SPECIES PEELS AND TISSUES 
    GHASEMI, KAMRAN; GHASEMI, YOSEF; ALI EBRAHIMZADEH, MOHAMMAD (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2009-07-07)
    Methanolic extracts of 13 commercially available citrus spp., peels and tissues growing in Iran were investigated for their antioxidant activity by DPPH method. IC50 for antioxidant activity ranged from 0.6-3.8 mg ml-1. ...
  • ANTIULCER AND ANTICONVULSANT ACTIVITY OF CROTON ZAMBESICUS 
    E OKOKON, JUDE; A NWAFOR, PAUL (ANTIULCER AND ANTICONVULSANT ACTIVITY OF CROTON ZAMBESICUS, 2009-10)
    The ethanolic root extract of Croton zambesicus was investigated for its potential to protect gastric mucosa against ulcers induced by indomethacin, ethanol and reserpine. The anticonvulsant activity of the root extract ...
  • ASSESSMENT OF ANTICOAGULANT EFFECT OF EVENING PRIMROSE OIL 
    RIAZ, AZRA; ALAM KHAN, RAFEEQ; PARVEEN AHMED, SHAHIDA (Karachi: Faculty of Pharmacy, University of Karachi, 2009-10-22)
    Effect of evening primrose oil (EPO) was assessed on coagulation parameters following 30 and 60 days administration of 90, 180 and 360 µl/kg oil to healthy rabbits of either sex. There was significant increase in all assays ...
  • BACTERIOCIN PRODUCTION BY INDIGENOUS MARINE CATFISH ASSOCIATED VIBRIO SPP. 
    SAEED ZAI, ARSALAN; AHMAD, SAMIA; AJAZ RASOOL, SHEIKH (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2009-04-08)
    Fifty strains of genus Vibrio were isolated (identified) from healthy and diseased marine catfish(es). The isolates were screened for bacteriocin (vibriocin) production. About 32% isolates were found bacteriocin producers. ...
  • BIOASSAY SCREENING OF THE ESSENTIAL OIL AND VARIOUS EXTRACTS FROM 4 SPICES MEDICINAL PLANTS 
    SHARIFIFAR, FARIBA; HASSAN MOSHAFI, MOHAMMAD; DEHGHAN- NUDEHE, GHOLAMREZA; AMERI, ALIEH; AMERI, ALIEH (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2009-07-15)
    Four commonly used spices plants in Iran were evaluated for cytotoxicity effect using Brine Shrimp Lethality (BSL) assay. Essential oils and various extracts of Heracleum persicum, Nigella arvensis, Cinnamomum zeylanicum ...
  • BIOAVAILABILITY OF CIPROFLOXACIN TABLETS IN HUMANS AND ITS CORRELATION WITH THE DISSOLUTION RATES 
    KHALID KHAN, MUHAMMAD; FARID KHAN, MUHAMMAD; KHAN, HAROON; MUSTAFA, G (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2009-07-17)
    Bioavailabilities of seven tablets of ciprofloxacin were determined. The co-rrelation between in-vivo bioavailability parameters and in-vitro dissolution rates were studied. Ciprofloxacin concentration from the blood was ...
  • BIOEQUIVALENCE STUDIES OF TWO BRANDS OF MELOXICAM TABLETS IN HEALTHY PAKISTANI VOLUNTEERS 
    FARID HASAN, SYED MUHAMMAD; HARRIS SHOAIB, MUHAMMAD; HASSAN, FOUZIA; REHMAN, INAM-UR (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2009-04-15)
    The pharmacokinetic parameters of two oral formulations of meloxicam tablets were compared in a randomized, single oral dose; two treatments cross over design in 12 healthy male volunteers belonging to Pakistan under ...
  • BIOLOGICAL SCREENING OF EUPHORBIA HELIOSCOPIA L. 
    UZAIR, M; LOOTHAR, B A; CHOUDHARY, B A (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2009-04-12)
    The present research is preliminary biological screening of Euphorbia helioscopia L. (Euphorbiaceae). Dichloromethane and methanol extracts of the aerial parts of the plant were investigated for their antioxidant, antifungal, ...
  • CAFFEIC ACID PHENETHYL ESTER DECREASES THE LEVEL OF S-100B PROTEIN AFTER MIDDLE CEREBRAL AFTER OCCLUSION IN RABBITS 
    SERARSLAN, YURDAL; BAL, RAMAZAN; ENES ALTUĞ, MUHAMMED; KONTAŞ, TÜNAY; MURAT MELEK, İSMET (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2009-07-14)
    Effects of caffeic acid phenethyl ester (CAPE) on the serum S-100B levels were studied as an index for brain damage after permanent middle cerebral artery (MCA) occlusion in rabbits. Twenty rabbits were divided into four ...
  • COMPARATIVE STUDY OF TWO BACTERIOCINS PRODUCED BY REPRESENTATIVE INDIGENOUS SOIL BACTERIA 
    SALEEM, FARAH; AHMAD, SAMIA; YAQOOB, ZOBIA; AJAZ RASOOL, SHEIKH (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2009-07-02)
    The aim of this research work was to identify and characterized the bacteriocins produced by soil-associated bacteria. Bacillocin from Bacillus brevis Bb and pyocin from Pseudomonas aeruginosa Pa were found bioactive only ...
  • A COMPARATIVE STUDY OF VARIOUS MICROENCAPSULATION TECHNIQUES: EFFECT OF POLYMER VISCOSITY ON MICROCAPSULE CHARACTERISTICS 
    MURTAZA, GHULAM; AHAMD, MAHMOOD; AKHTAR, NAVEED; RASOOL, FATIMA (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2009-07-10)
    It is a comparative study of salbutamol sulpahte-ethylcellulose microcapsules prepared by three different microencapsulation techniques i.e. coacervation thermal change, solvent evaporation and coacervation nonsolvent ...
  • COMPARISON OF HYPOTENSIVE AND HYPOLIPIDEMIC EFFECTS OF CATHARANTHUS ROSEUS LEAVES EXTRACT WITH ATENOLOL ON ADRENALINE INDUCED HYPERTENSIVE RATS 
    ARA, NAZNIN; RASHID, MAMUNUR; AMRAN, MD SHAH (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2009-07-05)
    The leaves extract of Catharanthus roseus was investigated for hypotensive and hypolipidemic effects in adrenaline-induced hypertensive rats (AIHR) and compared with those of Atenolol in a crossover design. The pharmacologically ...
  • DESIGN AND EVALUATION OF ITRACONAZOLE LOADED SOLID LIPID NANOPARTICULATE SYSTEM FOR IMPROVING THE ANTIFUNGAL THERAPY 
    MUKHERJEE, SWARUPANANDA; RAY, SUBHABRATA; THAKUR, RS (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2009-07-03)
    The objective of the study was to design and evaluate Itraconazole loaded solid lipid nanoparticles (SLNs) drug delivery system, where Itraconazole nanoparticles with suitable size ranges are expected to improve ...
  • DICLOFENAC INHIBITS PROLIFERATION BUT NOT NGF-INDUCED DIFFERENTIATION OF PC12 CELLS 
    RAJABALIAN, SAEED; SHAMSI MEIMANDI, MANZUMEH; BADINLOO, MARZIYEH (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2009-07-03)
    Diclofenac is a non-steroidal anti-inflammatory drug that is prescribed for treatment of rheumatic diseases and as an analgesic. Although the information about these side effects has been widely reported, little is know ...
  • DIURETIC EFFECT OF POWDERED CERASUS AVIUM (CHERRY) TAILS ON HEALTHY VOLUNTEERS 
    HOOMAN, NAKYSA; MOJAB, FARAZ; NICKAVAR, BAHMAN; POURYOUSEFI-KERMANI, POURAN (2009-10)
    In this study, the diuretic activity of powdered cherry stalk was evaluated in 13 healthy volunteers by means of their water balance. In addition to biochemical parameters, such as urinary electrolyte concentration, ...

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