Prunes are used by folks as a remedy of various diseases including hepatitis. A clinical trial was designed to see the effects of prunes (Prunus domestica) on liver function. 166 healthy volunteers were divided into ...
M, SARASWATHI; RM, ROHINI; RANAPRATHAPSINGH, RANAPRATHAPSINGH; NAYEEM, NAIRA(Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2010-10-18)
The intermediate Benzimidazo[1,2-c] quinazolin-6(5H)-thione (1) was obtained by cyclization of 2-(2’-
aminophenyl) benzimidazole with carbon disulfide. Mannich base (2a-d) of compound (1) was obtained on
treatment with ...
The purpose of the present study was to investigate the analgesic activity of ethanol extract of leaf, stem, and
their different fractions i.e. pet-ether, dichloromethane, and methanol fraction of Swertia chirata ...
ASLAM, KINZA; KALEEM KHOSA, M.; JAHAN, NAZISH; NOSHEEN, SOFIA(Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2010-10-16)
In this work, coumarin was synthesized by Perkin reaction using salicylaldehyde, acetic acid and sodium
acetate. Due to the misuse of acetic anhydride in narcotics synthesis, acetic acid was substituted for acetic
anhydride ...
Equilibrium water content (EWC), equilibrium swelling ratio (ESR) and mass gain ratio are the swelling
parameters that are useful for correlating drug release characteristics from polymeric films, barriers etc.
These ...
The aim of this study was to develop and validate an isocratic reversed phase high-performance liquid
chromatographic method for quantification of pizotifen malate in pharmaceutical solid dosage formulations.
Good ...
Tamarindus indica Linn was used as a traditional medicine for the management of diabetes mellitus in human
and experimental animals. This study investigated effects of aqueous extract of Tamarindus indica seeds
(AETIS) ...
Caesalpinia decapetala is a wild plant found in the Sub-Himalayan tract and planted in hedges throughout in
India. The bark of Caesalpinia decapetala is a rich source of tannins. It has been used in treatment of ...
SIDDIQI, AISHA; AHMAD KHAN, DILSHAD; AHMED KHAN, FAROOQ; KHALIQ NAVEED, ABDUL(Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2010-10-11)
Variations of cytochrome-P450 enzyme system (CYP2CP) are associated with impaired metabolism of
warfarin. The objective of our study was to estimate the frequency of genetic and allelic variants of CYP2C9 in
Punjabi ...
S. ELZANFALY, EMAN; NEBSEN, MARIANNE; K. RAMADAN, NESREEN(Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2010-10-10)
This work represents the simultaneous determination of thiamine hydrochloride (B1), pyridoxine hydrochloride
(B6) and cyanocobalamine (B12) by two different methods namely spectrophotometry multivariate calibration
and ...
Fifteen medicinal plant extracts were investigated for: total phenolic content and free radical scavenging effect
by DPPH and ABTS assays; anti-lipid peroxidation activity by TBARS; and for antiglycation activity. ...
RASOOL, RAFIA; A GANAI, BASHIR; AKBAR, SEEMA; N KAMILI, AZRA; MASOOD, AKBAR(Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2010-10-08)
Kashmiri medicinal plant (Prunella vulgaris) was analyzed for its chemical composition and amount of
bioactive constituents. The results showed that the herb contains on an average alkaloid (1120 mg %), saponins (350 mg ...
The cytotoxicity of cell-free culture filtrates of 31 isolates of Vibrio cholerae O1 and O139, 5 reference strains
and 26 clinical isolates, was tested on Madin Darby Bovine Kidney (MDBK) cells and Vero cells. The ...
OKOKON, JUDE E; A NWAFOR, PAUL(Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2010-10-06)
The ethanolic root extract of C. zambesicus (27-81mg/kg) was evaluated for antiiflammatory, analgesic and
antipyretic properties in mice. The extract (27-81mg/kg) demonstrated a weak antiinflammatory activity.
However, ...
A simple, specific and accurate reverse phase liquid chromatographic method has been developed for the
simultaneous determination of naproxen and ranitidine HCl. Both the drugs are official with British
Pharmacopoeia ...
A versatile, accurate, precise and economic method for simultaneous determination of simvastatin and
ezetimibe in fixed dose combination products was developed. The absorbance values at 236 nm and 234 nm of over line ...
A, JAFARZADEH; ZM, HASSAN; M, EBTEKAR; MOHAGHEGH-HAZRATI S; T, TIRAIHI(Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2010-10-03)
Severe suppression of the immune system is the major cause of infections following burn injury. The aim of this
study was to investigate the time-related alterations of immune responses following thermal injury in an ...
Present study is carried out to compare laboratory diagnostic methods of Cutaneous leishmaniasis (CL) for the
outdoor patients of Bolan Medical College Complex Hospital, Quetta, Balochistan. From November 2005 to
December ...
AHMED AL-ABBASI, FAHAD; IBRAHEEM AL-SIENI, ABDULBASIT(Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2010-10-01)
Non-CYP oxidase enzymes are important system in biotransformation of drugs and environmental pollutants.
Molybdenum containing oxidase enzymes such as aldehyde oxidase and xanthine oxidase are constitutive tissue enzymes ...
ALAM MAHMOOD, ZAFAR; SUALEH, MOHAMMAD; ZAFAR MAHMOOD, SAAD BIN; AHMED KARIM, MAHWISH(Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2010-01-20)
ABSTRACT More than 2000 plants have been listed in the Traditional (Herbal/Alternative) systems of medicine and some of these are providing comprehensive relief to the people suffering from cardio-vascular diseases, specially ...