Volume 23: Recent submissions

  • ANTIMICROBIAL ACTIVITY OF ROOT EXTRACT AND CRUDE FRACTIONS OF CROTON ZAMBESICUS 
    OKOKON, JUDE E; A NWAFOR, PAUL (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2010-01-20)
    The root extract and fractions of Croton zambesicus were screened for antimicrobial activity against some typed and pure cultures of bacterial and fungal species. These were carried out by the Plate -hole diffusion method ...
  • ANTIBACTERIAL EFFECT OF NSAIDS ON CLINICAL ISOLATES OF URINARY TRACT INFECTION AND DIABETIC FOOT INFECTION 
    AKHTER, TASNEEM; BAQAI, RAKHSHANDA; AZIZ, MUBASHAR (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2010-01-20)
    Non Steroidal Anti-inflammatory Drugs (NSAIDS) are a group of chemically dissimilar agents that have primary effect of inhibition of prostaglandin’s synthesis. Aspirin (Acetyl Salicylic Acid) is used as an analgesic, anti ...
  • PRONIOSOMES AS DRUG CARRIERS 
    SANKAR, V; RUCKMANI, K; DURGA, S; JAILANI, S (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2010-01-20)
    Approaches to stabilize niosomal drug delivery system without affecting its properties of merits have resulted in the development of the promising drug carrier, proniosomes. Proniosomes is dry formulation using suitable ...
  • IMMUNOGLOBULIN LEVELS OF VITILIGO PATIENTS 
    ALI, RUBAIYA; SHAMSUL AHSAN, MOHAMMAD; KALAM AZAD, ABUL; ASHIK ULLAH, MD.; BARI, WASIMUL; NAZRUL ISLAM, SHEIKH; YEASMIN, SABINA; HASNAT, ABUL (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2010-01-20)
    In the present study, the serum immunoglobulin profiles of vitiligo patients were compared with that of cohort control and evaluated the correlation between immunoglobulin level with their socioeconomic factors and nutritional ...
  • BONE MINERAL DENSITY AND VITAMIN D RECEPTOR POLYMORPHISM IN β-THALASSEMIA MAJOR 
    H EL-EDEL, RAWHIA; GHONAIM, MABROUK M; M ABO-SALEM, OSAMA; M EL-NEMR, FATHIA (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2010-01-20)
    Osteoporosis is the most prevalent bone complication in β-thalassemic patients despite regular transfusions and iron chelation therapy. Although its etiology is multi-factorial, genetic factors play an important role in ...
  • THE EFFECTS OF SOME PERMEABILITY ENHANCERS ON THE PERCUTANEOUS ABSORPTION OF LIDOCAINE 
    MOHAMMADI-SAMANI, SOLIMAN; JAMSHIDZADEH, AKRAM; MONTASERI, HASHEM; RANGBAR-ZAHEDANI, MOJGAN (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2010-01-20)
    Local anesthesia of the intact skin is difficult because of the barrier properties of skin to epicutaneous penetration of local anesthetic drugs. Using local anesthetics with combination of penetration enhancers could ...
  • IMMUNOMODULATORY EFFECTS OF ZERUMBONE ISOLATED FROM ROOTS OF ZINGIBER ZERUMBET 
    KEONG, YEAP SWEE; BANU ALITHEEN, NOORJAHAN; MUSTAFA, SHUHAIMI; ABDUL AZIZ, SURAINI; ABDUL RAHMAN, MASHITOH; MANAF ALI, ABDUL (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2010-01-20)
    In this study, the immunomodulatory effects of zerumbone isolated from Zingiber zerumbet were investigated by evaluating the effects of this compound towards the lymphocytes proliferation (mice thymocytes, mice splenocytes ...
  • SEASONAL VARIATION OF TOTAL PHENOLIC, ANTIOXIDANT ACTIVITY AND MINERALS IN FRESH TEA SHOOTS (CAMELLIA SINENSIS VAR. SINENSIS) 
    ERTURK, YASAR; ERCISLI, SEZAI; SENGUL, MEMNUNE; ESER, ZEYNEP; HAZNEDAR, AYHAN; TURAN, METIN (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2010-01-20)
    Seasonal variation of total phenolics, antioxidant activity and minerals in fresh tea shoots, consisting of one apical bud and two adjoining leaves sampled from Muradiye, Tuglali, Gundogdu, Enstitu 9, Hamzabey, Hayrat and ...
  • IMMUNOMODULATORY ACTIVITY OF METHANOLIC EXTRACT OF MORUS ALBA LINN. (MULBERRY) LEAVES 
    ESWARA, SHENDIGE; BHARANI, RAO; ASAD, MOHAMMED; SAMSON DHAMANIGI, SUNIL; CHANDRAKALA, GOWDA KALLENAHALLI (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2010-01-20)
    The leaves of Morus alba Linn. (Family: Moraceae) commonly known as mulberry are mainly used as food for the silkworms and they are sometimes eaten as vegetable or used as cattle fodder in different parts of the world. The ...
  • ANTIOXIDANT ACTIVITY OF AERIAL PARTS OF TRIBULUS ALATUS IN RATS 
    KADRY, H.; ABOU BASHA, L.; GINDI, O. EL; TEMRAZ, A. (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2010-01-20)
    The antioxidant activity of alcoholic extract of Tribulus alatus was investigated by determination of blood glutathione, serum ascorbic acid and serum superoxide dismutase in rats. All groups treated with aerial parts ...
  • EVALUATION OF ANTIGLYCOSIDASE AND ANTICHOLINESTERASE ACTIVITIES OF BOEHMERIA NIVEA 
    SANCHETI, SANDESH; SANCHETI, SHRUTI; SEO, SUNG-YUM (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2010-04-20)
    In this era, major community worldwide is suffering from diabetes type II, cancer and neurodegenerative disorders. To overcome these diseases, in the screening of Korean medicinal plants, we studied the whole plant of ...
  • IN VITRO ANTIMICROBIAL ACTIVITY OF FOUR FICUS CARICA LATEX FRACTIONS AGAINST RESISTANT HUMAN PATHOGENS (ANTIMICROBIAL ACTIVITY OF FICUS CARICA LATEX) 
    AREF, HOUDA LAZREG; HADJ SALAH, KARIMA BEL; CHAUMONT, JEAN PIERRE; FEKIH, ABDELWAHEB; AOUNI, MAHJOUB; SAID, KHALED (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2010-01-20)
    Methanolic, hexanoïc, chloroformic and ethyl acetate extracts of Ficus carica latex were investigated for their in vitro antimicrobial proprieties against five bacteria species and seven strains of fungi. The green fruit ...
  • FORMULATION AND EVALUATION OF CETIRIZINE DIHYDROCHLORIDE ORODISPERSIBLE TABLET 
    SUBRAMANIAN, S; SANKAR, V; MANAKADAN, ASHA ASOKAN; ISMAIL, SAREENA; ANDHUVAN, G (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2010-04-19)
    Cetirizine orodispersible tablets were prepared to achieve quick onset of action and for maximum bioavailability. Tablets were prepared using cetirizine along with camphor and mannitol in the proportion of 1:1:1, 1:1:3, ...
  • ANTIMICROBIAL EFFECTS OF BOESENBERGIA PANDURATA AND PIPER SARMENTOSUM LEAF EXTRACTS ON PLANKTONIC CELLS AND BIOFILM OF ORAL PATHOGENS 
    TAWEECHAISUPAPONG, SUWIMOL; SINGHARA, SUPAPORN; LERTSATITTHANAKORN, PILANTHANA; KHUNKITTI, WATCHAREE (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2010-04-18)
    Increasing awareness of hazards associated with the use of antibiotic and chemical agents has accelerated investigations into plants and their extracts as new sources of antimicrobial agents. Therefore, this study aimed at ...
  • SYNTHESIS OF SOME NOVEL ANALOGUES OF 4-(1-PYRROLIDINYL) PIPERIDINE AND THEIR EFFECT ON PLASMA GLUCOSE LEVEL 
    MUSHTAQ, NOUSHEEN; SAIFY, Z.S; AKHTAR, SHAMIM; ARIF, MUHAMMAD; HAIDER, SAIDA; SABA, NAZISH (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2010-04-17)
    In the present study some compounds of 4-(1-Pyrrolidinyl) Piperidine (I) have been synthesized. Structures of compounds were confirmed by using HNMR, IR, Mass and UV spectrophotometer techniques. All the derivatives (II, ...
  • STUDIES ON THE CHEMICAL COMPOSITION OF KOHL STONE BY X-RAY DIFFRACTOMETER 
    ULLAH, PERVAIZ HABIB; MAHMOOD, ZAFAR ALAM; SUALEH, MOHAMMAD; ZOHA, SMS (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2010-01-20)
    Use of Kohl (Surma) creates toxicity or protects eye, is one of the most controversial topic of modern medicines. However, modern researches show that kohl forms a thin film on the eye lens thus avoiding the direct contract ...
  • HYPOGLYCEMIC AND HYPOLIPIDEMIC EFFECTS OF AN AQUEOUS EXTRACT OF CHAMAEROPS HUMILIS LEAVES IN OBESE, HYPERGLYCEMIC AND HYPERLIPIDEMIC MERIONES SHAWI RATS 
    GAAMOUSSI, FARAH; H. ISRAILI, ZAFAR; LYOUSSI, BADIAÂ (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2010-04-16)
    Ethnopharmacological relevance: An aqueous concoction made from the leaves of Chamaerops humilis (L.) (dwarf fan palm), is used in the Moroccan traditional medicine for the treatment of diabetes, as well as a number of ...
  • PHARMACODYNAMIC INTERACTION OF GARLIC WITH PROPRANOLOL IN ISCHEMIA-REPERFUSION INDUCED MYOCARDIAL DAMAGE 
    MOHAMMED, SYED; ASDAQ, BASHEERUDDIN; INAMDAR, MOHAMMED NASEERUDDIN; ASAD, MOHAMMED (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2010-01-20)
    The present study was undertaken to explore the interaction of garlic homogenate (GH) with propranolol (PRO) on ischemia-reperfusion injury (IRI) in isolated rat heart preparation. Albino rats were treated with GH at three ...
  • OXYTOCIC EFFECTS OF THE AQUEOUS LEAF EXTRACT OF COSTUS LUCANUSIANUS – FAMILY COSTACEAE ON ISOLATED NON-PREGNANT RAT UTERUS 
    J OWOLABI, OMONKHELIN; KI OMOGBAI, ERIC; FALODUN, ABIODUN (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2010-04-15)
    Costus lucanusianus J. Braun (Costaceae) is a climbing herb, found mainly in the Niger Delta region of Nigeria. This plant is locally used in situations of pains, inflammation, dysmenorrhoea and in pyrexia. The purpose of ...
  • BUSPIRONE ATTENUATES TOLERANCE TO ANALGESIC EFFECT OF MORPHINE IN MICE WITH SKIN CANCER 
    MOHAJJEL NAYEBI, ALIREZA; REZAZADEH, HASSAN; NOURAFKAN, MOSTAFA (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2010-04-14)
    Adjuvant drugs that can delay tolerance to morphine analgesia may lead to improved management of pain in chronic disease such as cancer. This study was aimed to investigate effect of buspirone, as a partial agonist of 5- ...

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