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IN VITRO ANTIOXIDANT ACTIVITY OF ROOTS OF THESPESIA LAMPAS DALZ AND GIBS

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dc.contributor.author SWARAN B, SANGAME
dc.contributor.author KRISHNAN BR, BALA
dc.contributor.author DESHRAJ, CHUMBHALE
dc.contributor.author B, JAYAKAR
dc.date.accessioned 2022-11-29T05:09:22Z
dc.date.available 2022-11-29T05:09:22Z
dc.date.issued 2009-10-04
dc.identifier.citation Sangameswaran, B., Balakrishnan, B. R., Deshraj, C., & Jayakar, B. (2009). In vitro antioxidant activity of roots of Thespesia lampas Dalz and Gibs. Pak J Pharm Sci, 22(4), 368-72. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/14171
dc.description.abstract The free radical scavenging potential of roots of Thespesia lampas Dalz and Gibs was studied by different antioxidant models. Free radicals are implicated for more than 80 diseases including Diabetes mellitus, arthritis, cancer, ageing etc. In the treatment of theses diseases, antioxidant therapy has gained an utmost importance. Current research is directed towards finding naturally occurring antioxidant of plant origin. In Indian system of medicine, Thespesia lampas is an important medicinal plant and its root juice has been used in various ailments and as health tonic. To understand the mechanisms of pharmacological actions, the in vitro antioxidant activity of aqueous extract of The spesia lampas was investigated for the activity of scavenging superoxide anion radicals, nitric oxide radical and lipid peroxidation assay. In all the testing, a significant correlation existed between concentrations of the extract and percentage inhibition of free radicals, metal chelating, reducing power or inhibition of lipid peroxidation. These results clearly indicate that The spesia lampas is effective against free radical mediated diseases. en_US
dc.language.iso en en_US
dc.publisher Karachi: Faculty of Pharmacy, University of Karachi en_US
dc.subject Antioxidant en_US
dc.subject nitric oxide en_US
dc.subject Lipid peroxidation en_US
dc.subject superoxidation en_US
dc.subject Thespesia lampas en_US
dc.title IN VITRO ANTIOXIDANT ACTIVITY OF ROOTS OF THESPESIA LAMPAS DALZ AND GIBS en_US
dc.type Article en_US


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