dc.contributor.author |
SUTRADHAR, RANAJIT KUMAR |
|
dc.contributor.author |
RAHMAN, AKM MATIOR |
|
dc.contributor.author |
AHMAD, MESBAHUDDIN |
|
dc.contributor.author |
BACHAR, SITESH |
|
dc.contributor.author |
SAHA, ACHINTO |
|
dc.contributor.author |
ROY, TAPASHI |
|
dc.date.accessioned |
2022-11-29T05:16:12Z |
|
dc.date.available |
2022-11-29T05:16:12Z |
|
dc.date.issued |
2007-07-20 |
|
dc.identifier.citation |
Sutradhar, R. K., Rahman, A. M., Ahmad, M., CHANDRA, B. S., Saha, A., & Guha, S. K. (2006). Bioactive alkaloid from Sida cordifolia Linn. with analgesic and anti-inflammatory activities. |
en_US |
dc.identifier.issn |
1011-601X |
|
dc.identifier.uri |
http://142.54.178.187:9060/xmlui/handle/123456789/14175 |
|
dc.description.abstract |
The analgesic and anti-inflammatory activities of a new alkaloid, 1,2,3,9-tetrahydro-pyrrolo [2,1-b] quinazolin 3-ylamine (compound 1) isolated from Sida cordifolia Linn. were investigated in animal models. In the acetic acid induced writhing model, the compound 1 showed 25.4 (P<0.05) and 52.43% (P<0.01) inhibition of writhing response at doses of 25 and 50 mg/kg body weight respectively. The alkaloid also produced significant increase in the tail flick latency in radiant heat tail-flick method. In Carrageenan induced rat paw edema the compound 1 produced 16.93 and 24.43 % inhibition of paw edema at the doses of 25 and 50 mg/kg body weight respectively at the third hour of study. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi. |
en_US |
dc.subject |
Sida cordifolia |
en_US |
dc.subject |
analgesic |
en_US |
dc.subject |
anti-inflammatory activity. |
en_US |
dc.title |
ANTI-INFLAMMATORY AND ANALGESIC ALKALOID FROM SIDA CORDIFOLIA LINN. |
en_US |
dc.type |
Article |
en_US |