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ANTIOXIDANT AND FREE RADICAL SCAVENGING ACTIVITY OF H. OFFICINALIS L. VAR. ANGUSTIFOLIUS, V. ODORATA, B. HYRCANA AND C. SPECIOSUM

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dc.contributor.author ALI EBRAHIMZADEH, MOHAMMAD
dc.contributor.author NABAVI, SEYED MOHAMMAD
dc.contributor.author NABAVI, SEYED FAZEL
dc.contributor.author BAHRAMIAN, FATEMEH
dc.contributor.author BEKHRADNIA, AHMAD REZA
dc.date.accessioned 2022-11-29T05:47:05Z
dc.date.available 2022-11-29T05:47:05Z
dc.date.issued 2010-01-20
dc.identifier.citation Ebrahimzadeh, M. A., Nabavi, S. M., Nabavi, S. F., Bahramian, F., & Bekhradnia, A. R. (2010). Antioxidant and free radical scavenging activity of H. officinalis L. var. angustifolius, V. odorata, B. hyrcana and C. speciosum. Pak J Pharm Sci, 23(1), 29-34. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/14200
dc.description.abstract Extracts of 4 medicinal and aromatic plants were investigated for their antioxidant potency employing six various established in vitro system: H. officinalis L. var. angustifolius aerial parts, C. speciosum flowers, V. odorata and B. hyrcana leaves.With regard to IC50 values (µg/ ml), the order in DPPH radical-scavenging were CS (585.6) > HO (311) > VO (245.1) > and BH (113.1). Effectiveness in reducing powers were high and in a descending order of HO > CS > BH > VO (at the concentrations of 25-800 µg/ ml). IC50 for Fe2+ chelating ability were 188, 750 and 980 µg/ ml for VO, CS and HO, respectively. BH extract has shown only 38% inhibition at 800 µg/ ml. The extracts showed weak nitric oxide-scavenging activity. All extracts exhibited very low and moderate concentration-dependent antioxidant activity in FTC methods. IC50 for scavenging of H2O2 were 169 for BH, 175 for CS, 640 for VO and 663 µg/ ml for HO. The content of total phenolic compounds and flavonoids were measured in plant extracts. The data obtained in the in vitro models clearly establish the antioxidant potency of all extracts. en_US
dc.language.iso en en_US
dc.publisher Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi. en_US
dc.subject Antioxidant activity en_US
dc.subject DPPH en_US
dc.subject H. officinalis en_US
dc.subject C. speciosum en_US
dc.subject V. odorata en_US
dc.subject B. hyrcana. en_US
dc.title ANTIOXIDANT AND FREE RADICAL SCAVENGING ACTIVITY OF H. OFFICINALIS L. VAR. ANGUSTIFOLIUS, V. ODORATA, B. HYRCANA AND C. SPECIOSUM en_US
dc.type Article en_US


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