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ANTIMICROBIAL EFFECTS OF BOESENBERGIA PANDURATA AND PIPER SARMENTOSUM LEAF EXTRACTS ON PLANKTONIC CELLS AND BIOFILM OF ORAL PATHOGENS

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dc.contributor.author TAWEECHAISUPAPONG, SUWIMOL
dc.contributor.author SINGHARA, SUPAPORN
dc.contributor.author LERTSATITTHANAKORN, PILANTHANA
dc.contributor.author KHUNKITTI, WATCHAREE
dc.date.accessioned 2022-11-29T06:42:49Z
dc.date.available 2022-11-29T06:42:49Z
dc.date.issued 2010-04-18
dc.identifier.citation Taweechaisupapong, S., Singhara, S., Lertsatitthanakorn, P., & Khunkitti, W. (2010). Antimicrobial effects of Boesenbergia pandurata and Piper sarmentosum leaf extracts on planktonic cells and biofilm of oral pathogens. Pakistan Journal of Pharmaceutical Sciences, 23(2). en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/14218
dc.description.abstract Increasing awareness of hazards associated with the use of antibiotic and chemical agents has accelerated investigations into plants and their extracts as new sources of antimicrobial agents. Therefore, this study aimed at determining the effects of oil and 95% ethanol extracts of Boesenbergia pandurata rhizomes and Piper sarmentosum leaf against four oral pathogens which were Streptococcus mutans, Lactobacillus sp., Aggregatibacter actinomycetemcomitans and Candida albicans. Employing the disc diffusion and broth microdilution methods, the results showed that B. pandurata oil (BPO) was the most effective extract against C. albicans. Time-kill assay with the BPO demonstrated killing of C. albicans at concentrations equal to 2 and 2.5 times the MIC. The times required to reach the fungicidal endpoint at 2 and 2.5 times the MIC were 60 and 44 min, respectively. In addition, our results also demonstrated that the BPO possesses potent anti- Candida biofilm activity in vitro. Therefore, the BPO could be considered as a natural antifungal agent against Candida infections and has significant potential for further investigation. en_US
dc.language.iso en en_US
dc.publisher Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi en_US
dc.subject Boesenbergia pandurata en_US
dc.subject Piper sarmentosum en_US
dc.subject Antimicrobial activity en_US
dc.subject biofilm en_US
dc.subject Candida albicans, bacteria en_US
dc.title ANTIMICROBIAL EFFECTS OF BOESENBERGIA PANDURATA AND PIPER SARMENTOSUM LEAF EXTRACTS ON PLANKTONIC CELLS AND BIOFILM OF ORAL PATHOGENS en_US
dc.type Article en_US


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