Abstract:
Cetirizine orodispersible tablets were prepared to achieve quick onset of action and for maximum
bioavailability. Tablets were prepared using cetirizine along with camphor and mannitol in the proportion of
1:1:1, 1:1:3, and 1:1:6. The flow property of granules was found to be good for the formulation CZ2 (1:1:3).
The hardness and friability of all the formulations were found to be within the standard limit for orodispersible
tablets. Disintegration time was found to be rapid in formulation CZ2 (1:1:3).The in vitro dissolution time was
found to be 100% in 11 minutes for the formulation CZ2 (1:1:3).
