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Browsing Volume 24 by Title

Browsing Volume 24 by Title

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  • ANTAGONISTIC BACTERIA FROM LIVE CORALS, TUTICORIN COASTAL WATERS, SOUTHEASTERN INDIA 
    CHELLARAM, CHINNACHAMY; SREENIVASAN, SUBRAMANI; ANAND, THANKAPPAN PREM; KUMARAN, SEKARGOUNDER; KESAVAN, DHAMODARAN; PRIYA, GOVINDARAJAN (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2011-04-13)
    The objective of this study is to isolate and production of secondary metabolites with bioactive substances by coral reef (Acropora formosa and Favia palida) associated bacteria was carried out from the Tuticorin ...
  • ANTI DIABETIC EFFECT OF ACHYRANTHES RUBROFUSCA LEAF EXTRACTS ON ALLOXAN INDUCED DIABETIC RATS 
    GEETHA, GOVINDARAJULU; GOPINATHAPILLAI, PRASANTH KALAVALARASARIEL; SANKAR, VEINDRAMUTHU (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2011-04-15)
    The aqueous and ethanolic extracts of Achyranthes rubrofuca leaves (AR) were studied for their hypoglycemic activity. Thirty animals were taken and they were divided into five groups. First group acts as control, remaining ...
  • ANTI LIPID PEROXIDATION ACTIVITY OF PIPER TRIOICUM ROXB. AND PHYSALIS MINIMA L. EXTRACTS 
    DINAKARAN, SATHIS KUMAR; SARASWATHI, NARASIMHA RAJU; RAO NALINI, VENKATA RAMA; SRISUDHARSON; BODANAPU, VENKAT RAM REDDY; HARANI AVASARALA; DAVID BANJI (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2011-07-20)
    Attempt has been made to evaluate free radical scavenging activity of ethanolic extract of Piper trioicum Roxb. and Physalis minima L. individually. In this study goat liver has been used as lipid source. This in ...
  • ANTI-INFLAMMATORY AND ANALGESIC ACTIVITIES OF ETHANOLIC EXTRACT OF SPHAERANTHUS INDICUS LINN 
    ADAM ALI; NAQVI, SYED BAQIR SHYUM; SHAHNAZ GAUHAR; REHANA SAEED (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2011-07-20)
    The aim of the present study was to evaluate the intensity of the anti-inflammatory and analgesic activities of Sphaeranthus indicus on albino mice and rat of either sex. The flowers of S. indicus are an important herb ...
  • ANTI-MYCOBACTERIAL ACTIVITY OF GARLIC (ALLIUM SATIVUM) AGAINST MULTI-DRUG RESISTANT AND NON-MULTI-DRUG RESISTANT MYCOBACTERIUM TUBERCULOSIS 
    HANNAN, ABDUL; IKRAM ULLAH, MUHAMMAD; USMAN, MUHAMMAD; HUSSAIN, SHAHID; ABSAR, MUHAMMAD; JAVED, KHURSHEED (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2011-01-15)
    Emergence of multi-drug resistant (MDR) and extensively drug resistant (XDR) TB throughout the developing world is very disturbing in the present scenario of TB management. There is a fundamental need to explore alternative ...
  • ANTIDIABETIC AND HYPOLIPIDEMIC EFFECTS OF DIFFERENT FRACTIONS OF COCCINIA CORDIFOLIA L. ON NORMAL AND STREPTOZOTOCIN-INDUCED DIABETIC RATS 
    MD. ARIFUL ISLAM; KHAN, RAFIQUL ISLAM; SAROWAR HOSSAIN; KHURSHID ALAM; IMAM IBNE WAHED; BYTUL M. RAHMAN; ASM ANISUZZAMAN; SHARIF MD. SHAHEEN (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2011-07-20)
    The present study was carried out to observe the antidiabetic and hypolipidemic effects of petroleum-ether, ethyl acetate and chloroform fractions isolated from ethanolic extract of the leaves of Coccinia cordifolia ...
  • ANTIDIARRHOEAL AND ANTIULCER ACTIVITIES OF HIPPOCRATEA AFRICANA ROOT EXTRACT 
    OKOKON, JUDE EFIOM; AKPAN, HENRY DAN; UMOH, EMEM EKPO; EKAIDEM, ITEMOBONG SUNDAY (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2011-04-16)
    The effect of ethanol root extract of H. africana on experimentally induced diarrhoea and ulcer was studied in rodents. The extract (200 – 600mg/kg) considerably inhibited castor oil induced diarrhoea, small intestine transit ...
  • ANTIMICROBIAL ACTIVITY OF BACILLUS SP. STRAIN FAS1 ISOLATED FROM SOIL 
    MOSHAFI, MOHAMMAD HASAN; HAMID FOROOTANFAR; ALIEH AMER; MOJTABA SHAKIBAIE; DEHGHAN-NOUDEH, GHOLAMREZA; MOJDEH RAZAVI (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2011-07-20)
    During screening for antibiotic producing microorganisms from environmental soil samples, the supernatant of a bacterial isolate was found to have antibacterial and antifungal activity on the standard indicator species. ...
  • ANTIMICROBIAL ACTIVITY OF ERYTHROMYCIN AND CLARITHROMYCIN AGAINST CLINICAL ISOLATES OF ESCHERICHIA COLI, STAPHYLOCOCCUS AUREUS, KLEBSIELLA AND PROTEUS BY DISC DIFFUSION METHOD 
    WALI KHAN, NAVEED; HASSAN, FOUZIA; S NAQVI, BAQAR; FARID HASAN, SYED MUHAMMAD (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2011-01-05)
    Fifty clinical isolates comprising of Escherichia coli, Staphylococcus aureus, Klebsiella and Proteus were collected from different local pathological laboratories and their resistant pattern against two well known macrolides; ...
  • ANTINOCICEPTIVE AND ANTI-HYPERGLYCEMIC ACTIVITY OF METHANOL LEAF EXTRACT OF CYPERUS SCARIOSUS 
    ASRAFUL ALAM, MOHAMMAD; JAHAN, ROWNAK; RAHMAN, SHAHNAZ; KUMAR DAS, ASISH; RAHMATULLAH, MOHAMMED (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2011-01-10)
    The objective of the present study was to investigate the antinociceptive and anti-hyperglycemic activity of methanolic leaf extract of Cyperus scariosus. Antinociceptive activity was determined using a model of ...
  • ANTIOXIDANT ACTIVITY OF COVOLVULUS HYSTRIX VAHL AND ITS CHEMICAL CONSTITUENTS 
    DONIA, ABD EL RAHEIM MOHAMMED; ALQASOUMI, SALEH IBRAHIM; AWAAD, AMANI SHAFEEK; CRACKER, LYLE (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2011-04-08)
    Total alcohol and successive extracts (diethyl ether, chloroform, ethyl acetate and n-butanol) of Covolvulus hystrix Vahl were screened for their antioxidant activity using free radical 2-2- diphenyl-1-picrylhydrazyl (DPPH) ...
  • ANTIOXIDANT AND ANTIBACTERIAL ACTIVITIES OF SELECTED VARIETIES OF THAI MANGO SEED EXTRACT 
    KHAMMUANG, SARANYU; SARNTHIMA, RAKRUDEE (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2011-01-07)
    This study reports the antioxidant and antibacterial activities of four fresh mango seed extracts from Thai varieties. Total phenol contents determined by the Folin-ciocalteu method revealed the highest values to be ...
  • ANTISPASMODIC ACTIVITY OF TEUCRIUM STOCKSIANUM BOISS. 
    NIAZ ALI; SYED WADOOD ALI SHAH (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2011-04-12)
    The aim of the study was to explore the traditional antispasmodic use of Teucrium stocksianum on scientific grounds, and preliminary screen the specie for phytochemical constituents. Crude methanolic extract of aerial parts ...
  • BIOEQUIVALENCE STUDY OF TWO ORAL FORMULATIONS OF CLARITHROMYCIN IN HUMAN MALE SUBJECTS 
    KHAN, M KHALID; KHAN, MF; MUSTAFA, G; SUALAH, M (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2011-01-08)
    To assess the bioequivalence of tablets formulations of Clarithromycin 500mg each of test and reference products. A single post oral dose of each formulation was given to 14 male healthy volunteers. The study was conducted ...
  • CUMMULATIVE TOXICITIES ON LIPID PROFILE AND GLUCOSE FOLLOWING ADMINISTRATION OF ANTI-EPILEPTIC, ANTI-HYPERTENSIVE, ANTI-DIABETIC AND ANTI-ARRHYTHMIC DRUGS 
    FEROZ, ZEESHAN; ALAM KHAN, RAFEEQ; AFROZ, SYEDA (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2011-01-09)
    Reporting of undesirable drug reactions is a problem in all countries, even those with sophisticated drug regulatory bodies. However we can expect a horrible picture in developing countries like Pakistan where drug regulatory ...
  • CYTOTOXIC EFFECTS OF COMMERCIAL WHEATGRASS AND FIBER TOWARDS HUMAN ACUTE PROMYELOCYTIC LEUKEMIA CELLS (HL60) 
    ALITHEEN, NOORJAHAN BANU; OON, CHUAH LI; KEONG, YEAP SWEE; CHUAN, TAN KEE; LI, HO KET; YONG, HO WAN (Karachi: Pakistan Botanical Society, University of Karachi, 2011-07-20)
    ABSTRACT Cytotoxicity, the possible selective activity upon HL60 as well as the anti-proliferation effect of local health supplement wheatgrass and mixture of fibers were investigated in vitro using various cancerous ...
  • DESIGN AND EVALUATION OF A NEW FORMULATION OF ENALAPRIL MALEATE TABLET 
    REHANA BIBI; BAQIR SHYUM NAQVI; MUHAMMAD HARRIS SHOAIB; NAJIA RAHIM (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2011-04-18)
    Enalapril maleate, one of the Angiotensin converting enzyme (ACE) inhibitor is effective in the treatment of hypertension. Enalapril maleate is selected for the present study. The aim of this study was to develop a ...
  • DETERMINATION OF TOXIC METALS IN SOME HERBAL DRUGS THROUGH ATOMIC ABSORPTION SPECTROSCOPY 
    BUSHRA HINA; RIZWANI, GHAZALA HAFEEZ; SHAHID NASEEM (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2011-07-20)
    This study presents a picture of occurrence of heavy metals (Pb, Cd, Cu, Cr, Co, Fe, Ni, Zn) in some selected valuable herbal drugs (G. glabra, O. bracteatum, V. odorata , F. vulgare, C. cyminum, C. sativum, and ...
  • EFFECT OF ALUMINIUM METAL ON GLUTATHIONE (GSH) LEVEL IN PLASMA AND CYTOSOLIC FRACTION OF HUMAN BLOOD 
    KHAN, HAROON; KHAN, M.FARID; JAN, SYED UMER; ULLAH, NASEEM (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2011-01-03)
    Aluminium is being used in the medicines in the form of antacids. The Aluminium metal can be leached from our utensils and can harm the body for its side effects, if become available to the systemic circulation. So it ...
  • EFFECT OF NATURAL HONEY ON HUMAN PLATELETS AND BLOOD COAGULATION PROTEINS 
    ASIF AHMED; KHAN, RAFEEQ ALAM; AZIM, M. KAMRAN; SAEED, S. ARSHAD; MESAIK, M. AHMED; SHAKIL AHMED; IMRAN IMRAN (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2011-07-20)
    Present study was conducted to determine the effects of honey on blood hemostasis, in-vitro effect of honey was observed on platelet aggregation and blood coagulation employing, activated partial prothrombin time (aPTT), ...

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