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Browsing Issue 03 by Issue Date

Browsing Issue 03 by Issue Date

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  • CYTOTOXIC EFFECTS OF COMMERCIAL WHEATGRASS AND FIBER TOWARDS HUMAN ACUTE PROMYELOCYTIC LEUKEMIA CELLS (HL60) 
    ALITHEEN, NOORJAHAN BANU; OON, CHUAH LI; KEONG, YEAP SWEE; CHUAN, TAN KEE; LI, HO KET; YONG, HO WAN (Karachi: Pakistan Botanical Society, University of Karachi, 2011-07-20)
    ABSTRACT Cytotoxicity, the possible selective activity upon HL60 as well as the anti-proliferation effect of local health supplement wheatgrass and mixture of fibers were investigated in vitro using various cancerous ...
  • PHYTOCHEMICAL ANALYSIS, ANTIOXIDANT AND ANTIBACTERIAL EFFECTS OF SEA BUCKTHORN BERRIES 
    SAADIA CHAMAN; SYED, NAWAZISH-I-HUSAIN; ZEESHAN DANISH; KHAN, FARRAKH ZIA (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2011-07-20)
    Sea buckthorn berries are therapeutically used as folk medicine for a variety of diseases, however, the scientific evidence is hardly available to support their role. This study explored their chemical constituents and ...
  • EFFECT OF NATURAL HONEY ON HUMAN PLATELETS AND BLOOD COAGULATION PROTEINS 
    ASIF AHMED; KHAN, RAFEEQ ALAM; AZIM, M. KAMRAN; SAEED, S. ARSHAD; MESAIK, M. AHMED; SHAKIL AHMED; IMRAN IMRAN (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2011-07-20)
    Present study was conducted to determine the effects of honey on blood hemostasis, in-vitro effect of honey was observed on platelet aggregation and blood coagulation employing, activated partial prothrombin time (aPTT), ...
  • FORMULATION AND EVALUATION OF FICUS GLOMERATA MUCILAGE SUSTAINED RELEASE MATRIX TABLETS OF GLICLAZIDE 
    AHAD, HINDUSTAN ABDUL; KUMAR, CHITTA SURESH; BUDIDET, KISHORE KUMAR REDDY; BATTULA, SUMA PADMAJA; AYYAVALA, CHANDRA SEKHAR (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2011-07-20)
    The main aim of present investigation was to develop sustained release matrix tablets of Gliclazide using fruit mucilage from the plant Ficus glomerata. Varying ratios of drug and polymer viz. 1:0.25, 1:0.5, 1:0.75, ...
  • PHARMACOLOGICAL PROFILE OF SALVADORA PERSICA 
    MANSOOR AHMAD; HINA IMRAN; ZAHRA YAQEEN; ZAKIR-UR REHMAN; ATIQ-UR-RAHMAN; NUDRAT FATIMA; TEHMINA SOHAIL (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2011-07-20)
    This work was conducted to investigate the various pharmacological activities of Salvadora. persica family Salvadoracea and that includes anti inflammatory, analgesic, CNS, bleeding and clotting time activity by ...
  • NEUROPROTECTIVE EFFECT OF VITAMIN C AGAINST PTZ INDUCED APOPTOTIC NEURODEGENERATION IN ADULT RAT BRAIN 
    NASEER, MUHAMMAD IMRAN; IKRAM ULLAH; NAJEEB ULLAH; LEE, HAE YOUNG; CHEON, EUN WOO; JONGIL CHUNG; KIM, MYEONG OK (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2011-07-20)
    The present study was designed to observe the effect of PTZ on expression of caspsae-3, and to evaluate the neuroprotective role of vitamin C (vit-C) against PTZ-induced apoptotic neurodegeneration in adult rat brain. We ...
  • NUTRIENT COMPOSITION, PHENOLIC CONTENT AND FREE RADICAL SCAVENGING ACTIVITY OF SOME UNCOMMON VEGETABLES OF PAKISTAN 
    KHATTAK, KHANZADI FATIMA (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2011-07-20)
    Vegetables play a vital role in the prevention of human disease and in the improvement of general health as these contain vitamins, amino acids, fiber, antioxidants and minerals. In the present study, some less ...
  • DETERMINATION OF TOXIC METALS IN SOME HERBAL DRUGS THROUGH ATOMIC ABSORPTION SPECTROSCOPY 
    BUSHRA HINA; RIZWANI, GHAZALA HAFEEZ; SHAHID NASEEM (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2011-07-20)
    This study presents a picture of occurrence of heavy metals (Pb, Cd, Cu, Cr, Co, Fe, Ni, Zn) in some selected valuable herbal drugs (G. glabra, O. bracteatum, V. odorata , F. vulgare, C. cyminum, C. sativum, and ...
  • EVALUATION OF PHYTOCONSTITUENTS AND ANTI-NEPHROTOXIC AND ANTIOXIDANT ACTIVITIES OF MONOCHORIA VAGINALIS 
    SUBRAMANI PALANI; SUNDARARAJAN RAJA; KUMAR, RAMANUJAM PRAVEEN; RANGANATHAN SELVARAJ; KUMAR, BALASUBRAMANIAN SENTHIL (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2011-07-20)
    Monochoria vaginalis is an herbaceous medicinal plant used to treat, liver problems India. Acetaminophen is a commonly used analgesic and antipyretic agent which, at high doses, causes liver and kidney necrosis in man and ...
  • EFFECTS OF DEXAMETHASONE AND ATORVASTATIN ON ATRIAL SODIUM CURRENT AND ITS EARLY TACHYCARDIA-INDUCED ELECTRICAL REMODELING IN RABBITS 
    ROMAN LASZLO; MAREIKE SCHWIEBERT; MENZEL, KAREN ANNA; CHRISTIAN EICK; BIRGIT SCHREINER; JUERGEN SCHREIECK (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2011-07-20)
    ABSTRACT Purpose: Atrial fibrillation (AF) results in tachycardia-induced ionic remodeling. Pharmacological prevention of tachycardia-induced ionic remodeling not only with “classical” antiarrhythmics but also with drugs ...
  • FLAVONOIDS OF ENHYDRA FLUCTUANS EXHIBITS ANALGESIC AND ANTI-INFLAMMATORY ACTIVITY IN DIFFERENT ANIMAL MODELS 
    SANTANU SANNIGRAHI; MAZUMDER, UPAL KANTI; DILIPKUMAR PAL; SILPI LIPSA MISHRA; SUBHASIS MAITY (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2011-07-20)
    Enhydra fluctuans (Compositae), an edible semi aquatic herbaceous vegetable plant, widely used in traditional system of Indian medicine. Total flavonoids of E. fluctuans (TFEF) were screened for analgesic and antiinflammatory ...
  • ANTI LIPID PEROXIDATION ACTIVITY OF PIPER TRIOICUM ROXB. AND PHYSALIS MINIMA L. EXTRACTS 
    DINAKARAN, SATHIS KUMAR; SARASWATHI, NARASIMHA RAJU; RAO NALINI, VENKATA RAMA; SRISUDHARSON; BODANAPU, VENKAT RAM REDDY; HARANI AVASARALA; DAVID BANJI (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2011-07-20)
    Attempt has been made to evaluate free radical scavenging activity of ethanolic extract of Piper trioicum Roxb. and Physalis minima L. individually. In this study goat liver has been used as lipid source. This in ...
  • EVALUATION OF CEFACLOR ORAL SUSPENSIONS STABILITY USING REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY AND ANTIMICROBIAL DIFFUSION METHODS 
    TARAWNEH, KHALED AHMAD; HALASAH, ZINA ATALLAH; KHLEIFAT, ALI MOHMAD; BATARSEH, MUFEED ISSA; KHLEIFAT, KHALED MOHMAD; AL-MUSTAFA, AHMED HUSSEIN (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2011-07-20)
    The effect of temperature stresses on Cefaclor suspensions under different storage conditions for a duration of 14 days was tested. The degradation of Cefaclor was determined on the 2nd, 7th and 14th day after reconstitution ...
  • FORMULATION AND IN VITRO EVALUATION OF OFLOXACIN-ETHOCEL CONTROLLED RELEASE MATRIX TABLETS PREPARED BY WET GRANULATION METHOD: INFLUENCE OF CO-EXCIPIENTS ON DRUG RELEASE RATES 
    SHAH, SHEFAAT ULLAH; SHAH, KIFAYAT ULLAH; JAN, SYED UMER; KAMRAN AHMAD; ASIM-UR-REHMAN; ABID HUSSAIN; KHAN, GUL MAJID (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2011-07-20)
    Being controlled release dosage forms, tablets allow an improved absorption and release profiles of Ofloxacin. The fact that drugs with fine particles size can be compressed well after wetting, so in our research ...
  • HYPOPHAGIC AND HYPOLOCOMOTIVE EFFECTS OF METACHLORO PHENYL PIPERAZINE IN RATS TREATED WITH THEOPHYLLINE AND CAFFEINE 
    NAUSHEEN ALAM; HALEEM, DARAKSHAN JABEEN; RAHILA NAJAM; SYEDA HAIDER; AHMED, SHAHIDA PERVEEN (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2011-07-20)
    Long term intake of coffee is known to produce anxiety and suppression of appetite. 5- hydroxytryptamine (5- HT) acting via 5-HT-2C receptors elicits anorexia and anxiety. The present study is design to monitor metachloro ...
  • EFFECTS OF APOMORPHINE ON LOCOMOTIVE ACTIVITY AND MONOAMINE METABOLISM: A DOSE RELATED STUDY 
    HUMA IKRAM; SHOAIB AHMAD; HALEEM, DARAKHSHAN JABEEN (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2011-07-20)
    We have monitored dose dependent effects of apomorphine on motor activity and monoamine metabolism. Behavioral sensitization and craving, which develop upon repeated treatment with dopamine receptor agonist apomorphine, ...
  • HEPATOPROTECTIVE STUDIES ON HALOXYLON SALICORNICUM: A PLANT FROM CHOLISTAN DESERT 
    MAHMOOD AHMAD; SOFIA ERAM (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2011-07-20)
    The objective was to study the in-vivo hepatoprotective effect of aerial parts of Haloxylon salicornicum (Moq.) Bunge (Family: Chenopodiaceae) in order to validate its traditional use in hepatobiliary disorders, by ...
  • ANTIDIABETIC AND HYPOLIPIDEMIC EFFECTS OF DIFFERENT FRACTIONS OF COCCINIA CORDIFOLIA L. ON NORMAL AND STREPTOZOTOCIN-INDUCED DIABETIC RATS 
    MD. ARIFUL ISLAM; KHAN, RAFIQUL ISLAM; SAROWAR HOSSAIN; KHURSHID ALAM; IMAM IBNE WAHED; BYTUL M. RAHMAN; ASM ANISUZZAMAN; SHARIF MD. SHAHEEN (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2011-07-20)
    The present study was carried out to observe the antidiabetic and hypolipidemic effects of petroleum-ether, ethyl acetate and chloroform fractions isolated from ethanolic extract of the leaves of Coccinia cordifolia ...
  • ANTIMICROBIAL ACTIVITY OF BACILLUS SP. STRAIN FAS1 ISOLATED FROM SOIL 
    MOSHAFI, MOHAMMAD HASAN; HAMID FOROOTANFAR; ALIEH AMER; MOJTABA SHAKIBAIE; DEHGHAN-NOUDEH, GHOLAMREZA; MOJDEH RAZAVI (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2011-07-20)
    During screening for antibiotic producing microorganisms from environmental soil samples, the supernatant of a bacterial isolate was found to have antibacterial and antifungal activity on the standard indicator species. ...
  • ANTI-INFLAMMATORY AND ANALGESIC ACTIVITIES OF ETHANOLIC EXTRACT OF SPHAERANTHUS INDICUS LINN 
    ADAM ALI; NAQVI, SYED BAQIR SHYUM; SHAHNAZ GAUHAR; REHANA SAEED (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2011-07-20)
    The aim of the present study was to evaluate the intensity of the anti-inflammatory and analgesic activities of Sphaeranthus indicus on albino mice and rat of either sex. The flowers of S. indicus are an important herb ...

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