Ammad Ahmad Farooqi; Asma M Riaz; Shahzad Bhatti(Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-31)
This Review summarizes our current state of knowledge of the functional role of TRPC channels in health and
disease, with particular emphasis on current advancements in the field. Additionally, this review provides an ...
Mohamed Mansor Manan; Salmiah Mohd Ali; Khan, Muhammad Anwar Nawab; Sara Jafarian; Mohammed Abdul Hameed(Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-30)
This study is an observational cross-sectional study aimed to examine the possible demographic and social
characteristics of patients enrolled at the Methadone Maintenance Therapy Adherence Clinic (MMTAC) in Malaysia. ...
Ammad Ahmad Farooqi; Ghazala Butt; Gohar Yousaf; Muhammad Imran Qadir; Uzma Shaukat; Qaisar Mansoor; Madeeha Awan; Shahzad Bhatti; Almas Begum(Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-29)
Prostate cancer is a serious multidimensional disorder that arises because of misrepresentation of
signaling cascades and acquired resistance against apoptosis. It is progressively becoming more
insurmountable because ...
Qaisar Mansoor; Saira Shaheen; Uzma Javed; Uzma Shaheen; Irum Iqrar; Muhammad Ismail(Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-28)
Exploring healing power in plants emerged in prehistory of human civilization. Sustaining good health has
been achieved over the millions of years by use of plant products in various traditional sockets. A major contribution ...
Wan Mohd Azhar bin Wan Ibrahim; Eraj Humayun Mirza; Syed Fahad Akbar Ali(Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-27)
Heavy metals in cigarette tobacco such as iron may cause a serious damage on human health. Surveys showed that the accumulation of certain toxic heavy metals like cadmium, mercury, iron is very often due to the effect of ...
Zeeshan Feroz; Khan, Rafeeq Alam; Amber; Mahayrookh(Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-26)
For the past two decades, there has been an increasing interest in the investigation of medicinal plants as
potential sources of new therapeutic agents; hence it is crucial to recognize the apparent toxicity that might ...
Xu, Ren-ai; Hu, Lufeng; Wang, Zhe; Du, Xiaoxiang; Zhu, Haiyan; Zhang, Xiuhua(Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-25)
A “cocktail”of numerous probe drugs to assess the metabolic activity of the corresponding cytochrome P450
enzymes requires that there is no problem of interaction among them. Some interactions among probe drugs can appear ...
Abu-Gharbieh, Eman; Shehab, Naglaa Gamil; Khan, Saeed Ahmed(Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-23)
Micromeria fruticosa is used widely in many Mediterranean regions for various inflammatory conditions. The
aim of this work was to assess the anti-inflammatory and gastroprotective activities of the aqueous extract of ...
Farwa Sarwat; Nuzhat Ahmed; Afsheen Aman; Shah Ali Ul Qader(Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-22)
Leuconostoc are known to produce dextran, which have great commercial importance in chemical, medical
and food industry. The present study is an attempt to select the best medium for the isolation of indigenous dextran ...
Khan, Ibrar; Haroon Ahmad; Nasir Ali; Bashir Ahmad; Hamid Tanoli(Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-21)
The current study was aimed at screening the Bunium bulbocastanum for its antibacterial, antifungal,
phytotoxic and haemagglutination activities.The crude methanolic extract and n-hexane fraction showed significant (89%) ...
Prabhakara, Prabhu; Zenia, Teles; Marina, Koland; Shama, Khandige Prasanna; Girish, Shetty Nisha; Matapady, Nairy Harish(Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-20)
Site-specific delivery of anticancer based therapy of human cancers has led to several remarkable outcomes,
particularly in the therapy of breast cancer and lymphoma. Camptothecin, a plant secondary metabolite is widely ...
Syed Mudassir Haider Rizvi; Muhammad Abdul Azeem(Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-19)
Beta adrenoceptor agonists are well known for their potentiating effects on peak twitch and tetanic tension and
defatiguing effects on skeletal muscles. Adrenaline (ADR) is one of these agonist which is known for inotropism ...
Behzad Mesbahzadeh; Mohammad Ajalloueyan; Gholam Reza Kaka; Alireza Askari; Hasanalifard, Mahdieh(Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-18)
The use of rats in research academies to study deafness is widespread, meanwhile medicinal methods to
eliminate hair cells is also increasing. Thus, aminoglycosides and loop diuretics have grasped more attention. This ...
Zhou, Chuan; Shi, Youfei; Li, Jinlian; Zhang, Wen; Fu, Changqi; Wang, Yanmin; Liu, Yan; Liu, Jianzhu(Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-17)
The present study prepared the pulmonary fibrosis model in mice by using Bleomycin and carry out the
investigations on the effects of taurochenodeoxycholic acid (TCDCA) in preventing pulmonary fibrosis in mice.
Expression ...
Muhammad Qasim Samejo; Shahabuddin Memon; Muhammad Iqbal Bhanger; Khan, Khalid Mohammed(Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-16)
Aerva javanica (Burm.f.) Juss. ex Schult. seed essential oils were obtained by hydrodistillation (HD) and dry
steam distillation (SD) extracting methods and analyzed by using gas chromatography-mass spectrometry(GC-MS). ...
Najmur Rahman; Mansoor Ahmad; Muhammad Riaz; Mehjabeen; Noor Jahan; Rizwan Ahmad(Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-15)
Methanolic extract of medicinal herb Ajuga parviflora Benth. was evaluated for phytochemical screening (the
plant extract showed the presence of aromatic compounds, carbohydrates, glycosides, tannins, alkaloids, polyphenols, ...
Roopan, Selvaraj Mohana; Khan, Fazlur-Rahman Nawaz; Jin, Jong Sung(Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-14)
The larvicidal effect of series of 3-[(2-chloroquinolin-3-yl)methyl]quinazolin-4(3H)-ones, 5a-e, against
Chironomus tentans Fabricius has been investigated. The results showed that tested compounds demonstrated strong ...
Amara, Amro Abd-Al-Fattah(Karachi: Pakistan Botanical Society, University of Karachi, 2013-01-20)
The huge amount of information, the big number of scientists and their efforts, labs, man/hrs, fund, companies all and others factors build the success of the amazing new branch of genetic engineering the 'Protein Engineering' ...
Verma, Prabhakar Kumar; Kamboj, Vipan Kumar(Karachi: Pakistan Botanical Society, University of Karachi, 2013-01-20)
A rapid resolution high performance thin layer chromatography (HPTLC) method has been developed and validated for estimation of Olmesartan medoxomil in tablet formulations. This paper describes accurate, precise, specific ...
Dheeraj Baviskar; Rajesh Sharma; Dinesh Jain(Karachi: Pakistan Botanical Society, University of Karachi, 2013-01-20)
The present study was undertaken to investigate the effect of hydrophilic, plastic and hydrophobic types of polymers and their content level on the release profile of drug from matrix systems. To improve therapeutic ...