Volume 26: Recent submissions

  • Flaxseed – A miraculous defense against some critical maladies 
    Saeed Akhtar; Tariq Ismail; Muhammad Riaz (Karachi: Pakistan Botanical Society, University of Karachi, 2013-01-20)
    Presence of omega-3, omega-6 rich oil, alpha-linoleic acid, dietary fibers, secoisolariciresinol diglucoside, protein and minerals in flaxseed constitute a very strong basis for the utilization of flaxseed in various food ...
  • Characterization and biological studies of bis- and tera-acetyl derivatives of hydrocarbon-bridged Diamines-I 
    Naheed Haque; Izhar Hussain (Karachi: Pakistan Botanical Society, University of Karachi, 2013-01-20)
    A systematic study of the pharmaceutically important, double ended, chelating agents of the types CH3CONH(CH2)nNHCOCH3 and (CH3CO)2N(CH2)n N(COCH3)2, where n= 2, 3, 4, 5 and 6, prepared by the bis- and tetra-acetylation ...
  • Antibacterial effect of mango (Mangifera indica Linn.) leaf extract against antibiotic sensitive and multi-drug resistant Salmonella typhi 
    Abdul Hannan; Samra Asghar; Tahir Naeem; Muhammad Ikram Ullah; Ijaz Ahmed; Syeda Aneela; Shabbir Hussain (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-09)
    Alternative herbal medicine has been used to treat various infections from centuries. Natural plants contain phytoconstituents having similar chemical properties as of synthetic antibiotics. Typhoid fever is a serious ...
  • Spray-dried gastroretentive floating microparticles: Preparation and in vitro evaluation 
    Rao, Boggarapu Prakash; Mathews, Rashmi; Krishna, Karedla Phani; Baby, Beny; Poornima (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-08)
    The full factorial design was employed to evaluate contribution of drug: polymer and Eudragit RS 100: Eudragit RL 100 on entrapment efficiency, time for maximum drug release, percentage of drug release. Floating microparticles ...
  • Cytotoxicity of alkaloids isolated from Peganum harmala seeds 
    Fatima Lamchouri; Mustapha Zemzami; Jossang, Akino; Settaf, Abdellatif; Zafar H Israili; Lyoussi, Badiaa (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-07)
    Ethnopharmacological relevance: Peganum harmala is used in traditional medicine to treat a number of diseases including cancer. Our preliminary studies show that the alkaloidal extract of PH seed is cytotoxic to several ...
  • Effect of Grewia asiatica fruit on Glycemic index and phagocytosis tested in healthy human subjects 
    Muhammad Ahmed, Mesaik; Asif Ahmed; Khalid, Ahmed Shukralla; Siddiqui, Afaq Ahmed; Shahida Perveen; Muhammad Kamran, Azim (Karachi: Pakistan Botanical Society, University of Karachi, 2017-07-20)
    The Grewia asiatica (commonly known as Phalsa or Fasla) is a shrub or small tree found in southern Asia. It produces purple to black color fruit when ripe. In folk medicine the edible Grewia asiatica fruit is used in a ...
  • Carbopol 934, 940 and Ultrez 10 as viscosity modifiers of palm olein esters based nano-scaled emulsion containing ibuprofen 
    Ghassan Zuhair, Abdullah; Abdulkarim, Muthanna Fawzy; Chitneni Mallikarjun; Mahdi, Elrashid Saleh; Mahiran Basri; Sattar, Munavvar Abdul; Noor, Azmin Mohd (Karachi: Pakistan Botanical Society, University of Karachi, 2017-07-20)
    Micro-emulsions and sometimes nano-emulsions are well known candidates to deliver drugs locally. However, the poor rheological properties are marginally affecting their acceptance pharmaceutically. This work aimed to modify ...
  • Isolation and characterization of irritant components of Euphorbia pilulifera L. 
    Syed Saeed-ul-Hassan; Muhammad Khalil-ur-Rehman; Uzma Niaz; Saeed, Muhammad Asif; Khalid Hussain; Rao, Saeed Ahmed; Irshad Ahmed (Karachi: Pakistan Botanical Society, University of Karachi, 2017-07-20)
    Euphorbia pilulifera is commonly found weed along road sides and loamy soils. This weed is commonly used as treatment of female disorders and respiratory problems. The latex of this weed causes irritation on hand on contact. ...
  • Synthesis, in vitro antibacterial and antifungal activity of some n-acetylated and non-acetylated pyrazolines 
    Muhammad Baseer; Ansari, Farzana Latif; Zaman Ashraf (Karachi: Pakistan Botanical Society, University of Karachi, 2017-07-20)
    Fourteen new N-acetylated and non-acetylated pyrazoline derivatives were synthesized by reacting chalcones with hydrazine in the presence of absolute ethanol however reaction was carried out in the presence of glacial ...
  • Reduction of Methylene Green by EDTA: A relation between dielectric constant of medium and activated state 
    Noshab Qamar; Rafia Azmat; Raheela Naz (Karachi: Pakistan Botanical Society, University of Karachi, 2017-07-20)
    Kinetics of an alkaline reduction of the methylene green with ethylenediaminetetraaceticacid (EDTA) as a role of dielectric constant of the medium with anecdotal ionic strength in a diverse solvent system (aqueous mixtures ...
  • Isolation and characterization of different strains of Bacillus licheniformis for the production of commercially significant enzymes 
    Maria Ghani; Asma Ansari; Afsheen Aman; Rashida Rahmat Zohra; Nadir Naveed Siddiqui; Shah Ali Ul Qader (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-06)
    Utilization of highly specific enzymes for various industrial processes and applications has gained huge momentum in the field of white biotechnology. Selection of a strain by efficient plate-screening method for a specific ...
  • Identification of Sulfamoylbenzamide derivatives as selective Cathepsin D inhibitors 
    Waseem Ahmed; Khan, Ishtiaq Ahmad; Muhammad Nadeem Arshad; Waseeq Ahmad Siddiqui; Muhammad Abdul Haleem; Muhammad Kamran Azim (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-05)
    Aspartic proteases play very important role in post translational processing of proteins and several of them are essential for organism’s viability. Here we present the enzyme inhibition activities of different ...
  • Prolonged preconditioning with natural honey against myocardial infarction injuries 
    Eteraf-Oskouei, Tahereh; Shaseb, Elnaz; Ghaffary, Saba; Moslem Najafi (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-04)
    Potential protective effects of prolonged preconditioning with natural honey against myocardial infarction were investigated. Male Wistar rats were pre-treated with honey (1%, 2% and 4%) for 45 days then their hearts were ...
  • Hypoglycaemic effects of alcoholic root extract of Borassus flabellifer (Linn.) in normal and diabetic rats 
    Debnath, Titas; Radhakrishnan, Rajesh; Gopal, Murugananthan; Sahil Talwar; K, Nandakumar (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-03)
    The objective of the study was to investigate the alcoholic (ALEBF) extract of B. flabellifer for their hypoglycaemic effects in normal and diabetic rats. Diabetes was induced in rats by single dose administration of ...
  • Counter irritant activity of Carthamus oxycantha 
    Syed Saeed ul Hassan; Imran Waheed; Muhammad Khalil-ur-Rehman; Uzma Niaz; Muhammad Asif Saeed (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-02)
    Many locally occurring species of Asteraceae are used as medicinal plants by various tribal and ethnic communities in Pakistan. Carthamus oxycantha is often occurs as weed in cultivated fields. Folk medicines indicated ...
  • Formulation development and evaluation of Diltiazem HCl sustained release matrix tablets using HPMC K4M and K100M 
    Faaiza Qazi; Muhammad Harris Shoaib; Rabia Ismail Yousuf; Tanveer Mustafa Qazi; Zafar Alam Mehmood; Syed Muhammad Farid Hasan (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-01)
    The aim of this study was to develop a sustained release hydrophilic matrix tablet of Diltiazem HCl and evaluates the effect of formulation variables (e.g. lubricant, binder, polymer content and viscosity grades of HPMC) ...
  • Chemical and antimicrobial studies on the essential oil from Salvia santolinifolia Boiss. 
    Muhammad Nadir; Munawwer Rasheed; Sherwani, Sikandar Khan; Kazmi, Shahana Urooj; Ahmad, Viqar Uddin (Karachi: Pakistan Botanical Society, University of Karachi, 2017-07-20)
    In view of the reputation of genus Salvia in folklore medicine and its abundance in our region, the chemical composition and antimicrobial activity of essential oil from S. santolinifolia Boiss. was analyzed. Chemical ...
  • Development and characterisation of metformin loaded spray dried Bora rice microspheres 
    Sharma, Hemanta Kumar; Jadavesh Mohapatra; Nath, Lila Kanta (Karachi: Pakistan Botanical Society, University of Karachi, 2017-07-20)
    Bora rice, a glutinous rice, is grown in Assam (a north eastern state of India) and is used traditionally for various purposes. The rationale of this study was to prepare and to assess Metformin loaded mucoadhesive spray ...
  • Current efficacy of antibiotics against Klebsiella isolates from urine samples – A multi-centric experience in Karachi 
    Abdullah, Farhan Essa; Ammara Mushtaq; Mubashira Irshad; Hiba Rauf; Noureen Afzal; Abdur Rasheed (Karachi: Pakistan Botanical Society, University of Karachi, 2017-07-20)
    Due to emergence of bacterial resistant strains, the effectiveness of current antibiotic treatment without culture/sensitivity testing is questionable. Our study aims to assess the present sensitivity profiles of Klebsiella ...
  • In vitro efficacy of Colistin against multi-drug resistant Pseudomonas aeruginosa by minimum inhibitory concentration 
    Gill, Maria Mushtaq; Rao, Javaid Usman; Fatima Kaleem; Afreenish Hassan; Ali Khalid; Rabia Anjum (Karachi: Pakistan Botanical Society, University of Karachi, 2017-07-20)
    Multi-drug resistant bacteria are an important cause of mortality and morbidity. In the management of various infections, timely detection and appropriate treatment, in accordance with the culture and sensitivity reports ...

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