Issue 04: Recent submissions

  • Green tea catechins based functional drink (Green cool) improves the antioxidant status of SD rats fed on high cholesterol and sucrose diets 
    Rabia Shabir Ahmad; Butt, Masood Sadiq; Nuzhat Huma; Muhammad Tauseef Sultan (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-10)
    In the recent epoch, functional and nutraceuticals foods are gaining wide range of acceptability from the consumers. In the present research investigation, efforts were directed to exploit the green tea phytochemicals. ...
  • Trace element geochemistry of Manilkara zapota (L.) P. Royen, fruit from winder, Balochistan, Pakistan in perspective of medical geology 
    Salma Hamza; Shahid Naseem; Erum Bashir; Ghazala H Rizwani; Bushra Hina (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-24)
    An integrated study of rocks, soils and fruits of Manilkara zapota (L.) (Sapotaceae) of Winder area have been carried out to elaborate trace elements relationship between them. The igneous rocks of the study area have ...
  • Antibacterial effect of mango (Mangifera indica Linn.) leaf extract against antibiotic sensitive and multi-drug resistant Salmonella typhi 
    Abdul Hannan; Samra Asghar; Tahir Naeem; Muhammad Ikram Ullah; Ijaz Ahmed; Syeda Aneela; Shabbir Hussain (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-09)
    Alternative herbal medicine has been used to treat various infections from centuries. Natural plants contain phytoconstituents having similar chemical properties as of synthetic antibiotics. Typhoid fever is a serious ...
  • Spray-dried gastroretentive floating microparticles: Preparation and in vitro evaluation 
    Rao, Boggarapu Prakash; Mathews, Rashmi; Krishna, Karedla Phani; Baby, Beny; Poornima (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-08)
    The full factorial design was employed to evaluate contribution of drug: polymer and Eudragit RS 100: Eudragit RL 100 on entrapment efficiency, time for maximum drug release, percentage of drug release. Floating microparticles ...
  • Cytotoxicity of alkaloids isolated from Peganum harmala seeds 
    Fatima Lamchouri; Mustapha Zemzami; Jossang, Akino; Settaf, Abdellatif; Zafar H Israili; Lyoussi, Badiaa (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-07)
    Ethnopharmacological relevance: Peganum harmala is used in traditional medicine to treat a number of diseases including cancer. Our preliminary studies show that the alkaloidal extract of PH seed is cytotoxic to several ...
  • Isolation and characterization of different strains of Bacillus licheniformis for the production of commercially significant enzymes 
    Maria Ghani; Asma Ansari; Afsheen Aman; Rashida Rahmat Zohra; Nadir Naveed Siddiqui; Shah Ali Ul Qader (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-06)
    Utilization of highly specific enzymes for various industrial processes and applications has gained huge momentum in the field of white biotechnology. Selection of a strain by efficient plate-screening method for a specific ...
  • Identification of Sulfamoylbenzamide derivatives as selective Cathepsin D inhibitors 
    Waseem Ahmed; Khan, Ishtiaq Ahmad; Muhammad Nadeem Arshad; Waseeq Ahmad Siddiqui; Muhammad Abdul Haleem; Muhammad Kamran Azim (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-05)
    Aspartic proteases play very important role in post translational processing of proteins and several of them are essential for organism’s viability. Here we present the enzyme inhibition activities of different ...
  • Prolonged preconditioning with natural honey against myocardial infarction injuries 
    Eteraf-Oskouei, Tahereh; Shaseb, Elnaz; Ghaffary, Saba; Moslem Najafi (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-04)
    Potential protective effects of prolonged preconditioning with natural honey against myocardial infarction were investigated. Male Wistar rats were pre-treated with honey (1%, 2% and 4%) for 45 days then their hearts were ...
  • Hypoglycaemic effects of alcoholic root extract of Borassus flabellifer (Linn.) in normal and diabetic rats 
    Debnath, Titas; Radhakrishnan, Rajesh; Gopal, Murugananthan; Sahil Talwar; K, Nandakumar (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-03)
    The objective of the study was to investigate the alcoholic (ALEBF) extract of B. flabellifer for their hypoglycaemic effects in normal and diabetic rats. Diabetes was induced in rats by single dose administration of ...
  • Counter irritant activity of Carthamus oxycantha 
    Syed Saeed ul Hassan; Imran Waheed; Muhammad Khalil-ur-Rehman; Uzma Niaz; Muhammad Asif Saeed (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-02)
    Many locally occurring species of Asteraceae are used as medicinal plants by various tribal and ethnic communities in Pakistan. Carthamus oxycantha is often occurs as weed in cultivated fields. Folk medicines indicated ...
  • Formulation development and evaluation of Diltiazem HCl sustained release matrix tablets using HPMC K4M and K100M 
    Faaiza Qazi; Muhammad Harris Shoaib; Rabia Ismail Yousuf; Tanveer Mustafa Qazi; Zafar Alam Mehmood; Syed Muhammad Farid Hasan (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2013-07-01)
    The aim of this study was to develop a sustained release hydrophilic matrix tablet of Diltiazem HCl and evaluates the effect of formulation variables (e.g. lubricant, binder, polymer content and viscosity grades of HPMC) ...

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