Issue 01: Recent submissions

  • Antioxidant and hypoglycemic activity of strawberry fruit extracts against alloxan induced diabetes in rats 
    Abdulazeez, Sheriff Sheik; Ponnusamy, Ponmurugan (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2016-01-20)
    The strawberries (Fragaria x ananassa) of Rosaceae family are an accomplished source of bioactive compounds such as ascorbic acid and diverse range of polyphenols including anthocyanins, phenolic acids, flavonols, ellagitannins ...
  • Sensitivity pattern of ceftriaxone against different clinical isolates 
    Bushra, Rabia; Sial, Ali Akbar; Rizvi, Mehwish; Shafiq, Yousra; Aslam, Nousheen; Bano, Nusrat (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2016-01-20)
    Emerging resistance against broad-spectrum antibiotics for standard empiric therapy is a global concern. Ceftriaxone (broad spectrum, third generation cephalosporin) is widely used in tertiary care settings to treat severe ...
  • Qadir test 
    Qadir, Muhammad Imran (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2016-01-20)
    The present diagnostic tests for cancers are expensive and are not accessible by poor. Therefore, it was necessary to explore a diagnostic test accessible by general public. Plasma lipid profile is decreased in all the ...
  • Demographic profiles and sleep quality among patients on methadone maintenance therapy (MMT) in Malaysia 
    Zahari, Zalina; Siong, Lee Chee; Musa, Nurfadhlina; Azhar, Muhammad; Yasin, Muhammad; Ismail, Rusli (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2016-01-20)
    Poor sleep quality was frequently reported by opioid dependence patients during methadone maintenance therapy (MMT). The study investigated a sample of patients on MMT to investigate the severity and prevalence of sleep ...
  • Ethanolic extract of Nigella sativa protects Fe(II) induced lipid peroxidation in rat’s brain, kidney and liver homogenates 
    Hassan, Waseem; Noreen, Hamsa; Ullah Khalil, Shafqat; Hussain, Arshad; Rehman, Shakilla; Sajjad, Shagufta; Rahman, Ata Ur; BT da Rocha, Joao (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2016-01-20)
    The study describes the effect of ethanolic extract of Nigella sativa against Fe(II) induced lipid peroxidation. Basal and Fe(II) induced thiobarbituric acid reactive species (TBARS) production was significantly inhibited ...
  • Biological activities of some Acacia spp. (Fabaceae) against new clinical isolates identified by ribosomal RNA gene-based phylogenetic analysis 
    Fawzy Mahmoud, Mahmoud; Abdullah Alrumman, Sulaiman; El-Latif Hesham, Abd (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2016-01-20)
    Nowadays, most of the pathogenic bacteria become resistant to antibiotics. Therefore, the pharmaceutical properties of the natural plant extracts have become of interest to researchers as alternative antimicrobial agents. ...
  • Development of cetyl dimethicone based water-in-oil emulsion containing botanicals: Physical characteristics and stability 
    Waqas, Muhammad Khurram; Akhtar, Naveed; Akhtar Shah, Pervaiz; Zeeshan, Muhammad; Ali Shah, Arshad; Braga, Valdir de Andrade; Ali Khan, Barkat (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2016-01-20)
    The aim of current research was to develop a water-in-oil emulsion containing grape seed extract for application in cosmeceuticals. Finally grinded dried grape seeds powder was extracted with hydro alcoholic mixture. ...
  • Antioxidant studies on monosubstituted chalcone derivatives - understanding substituent effects 
    Prabhakar, Visakh; Iqbal, Hiba; Balasubramanian, Ranganathan (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2016-01-20)
    An overproduction of reactive oxygen species beyond basal levels generated continuously in the body as part of natural metabolic processes often results in serious and diverse disease conditions including cancer. Chalcones ...
  • Alternative treatment for iron deficiency anemia: Irocbin versus sherbat Faulad 
    Ayaz, Sultan; Usmanghani, Khan; Nazar, Halima (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2016-01-20)
    The widespread reason of anemia is Iron deficiency in Pakistan and even worldwide. A clinical trial was undertaken to assess the efficacy of Irocbin formulation for the treatment of iron deficiency anemia as compared to ...
  • Effects of spironolactone towards rabbit atrial remodeling with rapid pacing 
    Wang, Lian-Fa; Gu, Lei; Xun Huang, Meng; Bing Zhou, Wen; Li, Hua; Zhu Zhang, Bang (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2016-01-20)
    This study aimed to observe the effects of spironolactone towards the rabbit atrial remodeling with rapid atrial pacing (RAP). 30 rabbits were randomly divided into control group, RAP group and spironolactone group, with ...
  • In vitro antimicrobial activities of different solvent extracted samples from Iris germinica 
    Uzair, Amjed; Bakht, Jehan; Iqbal, Arshad; Naveed, Khalid; Ali, Naushad (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2016-01-20)
    : Antibacterial and antifungal activities of different solvents extracted samples of Iris germinica were carried out through disc diffusion assay. For this purpose five different solvent extracts were prepared with two ...
  • Enhancement of sodium taurocholate to the absorption of cefquinome 
    Yu, Qinghua; Cao, Yufei; feng Liu, Li; xiang Jiang, Shan; Yang, Qian (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2016-01-20)
    The objective of the research was to detect the enhancement effect of sodium taurocholate on the absorption of cefquinome both in Caco-2 cells and rats. The absorption efficiency of cefquinome was determined by high ...
  • Biosynthesis, characterization and antimicrobial action of silver nanoparticles from root bark extract of Berberis lycium Royle 
    Mehmood, Ansar; Murtaza, Ghulam; Mahmood Bhatti, Tariq; Kausar, Rehana; Jamil Ahmed, d Muhammad (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2016-01-20)
    Various biological methods are being recognized for the fabrication of silver nanoparticles, which are used in several fields. The phytosynthesis of nanoparticles came out as a cost effective and enviro-friendly approach. ...
  • The effect of zinc supplementation on the urinary excretion of elements in female athletes 
    Eskici, Gunay; Gunay, Mehmet; Baltaci, Abdulkerim Kasim; Mogulkoc, Rasim (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2016-01-20)
    This study was carried out to find out how oral zinc supplementation to elite athletes affects the element changes in the urine. The study registered 10 female athletes who were on the women’s volleyball team of Gazi ...
  • Ondansetron: A newer aspect of dose response relationship on ileal smooth muscles of rabbit 
    Afzal, Ayesha; Khan, Bushra Tayyaba; Bakhtiar, Salman (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2016-01-20)
    There are several life threatening deadly diseases in our world but ‘Cancer’ out powers them all in recent years. Chemotherapy may be used on its own or an adjunct to other forms of therapy. Despite the advancement in ...
  • Effect of lipid extracts of Nigella sativa L. seeds on the liver ATP reduction and alpha-glucosidase inhibition 
    Sobhi, Widad; Stevigny, Caroline; Duez, Pierre; Calderon, Bedro Buc; Atmani, Djebbar; Benboubetra, Mustapha (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2016-01-20)
    Various extracts from the seeds of Nigella sativa have been used in traditional folk medicine to treat inflammation, liver disorders and arthritis. These seeds have been experimentally shown to possess antioxidant and ...
  • Pharmacognostic studies on Taxus baccata L.: A brilliant source of Anti-cancer agents 
    Asif, Muhammad; Rizwani, Ghazala H.; Zahid, Hina; Khan, Zahid; Qasim, Rao (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2016-01-20)
    The present investigation was undertaken to establish standardization profile of Taxus baccata L. with the help of pharmacognostic parameters, which is not done before. T. baccata (Taxaceae), is native to Europe, is an ...
  • Antioxidant study of flavonoid derivatives from the aerial parts of Rhus natalensis growing in Saudi Arabia 
    Alqasoumi, Saleh Ibrahim; Basudan, Omer Ahmed; Alam, Prawez; Abdel-Kader, Maged Saad (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2016-01-20)
    Phytochemical study of the CH2Cl2 soluble fraction of the aerial parts of R. natalensis resulted in the isolation and identification of six flavonoid derivatives, β-amyrin and β-sitosterol glucoside (daucosterol). The ...
  • Palm oil and ground nut oil supplementation effects on blood glucose and antioxidant status in alloxan-induced diabetic rats 
    Adewale, Olabiyi Folorunso; Isaac, Olatunji Olusola; Temitope Tunmise, Makinwa; Oluwafemi Omoniyi, Oguntibeju (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2016-01-20)
    This study investigated the effects of two common cooking oils (palm oil, PO) and (groundnut oil, GO) supplementation on the antioxidant status and diabetic indices in Alloxan (100mg/kg) induced diabetic Wistar rats. A ...
  • Analgesic activity of alkyl piperidine derivatives 
    Jahan, Sarwat; Akhtar, Shamim; Kamil, Arfa; Mushtaq, Nousheen; Saify, Zafar Saied; Arif, Muhammad (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2016-01-20)
    Piperidine is the most significant scaffold which reveals therapeutic potential because of its conformationally flexible nature. During the course of present investigations synthetic quaternary salts of alkyl piperidine ...

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