dc.contributor.author |
POVICHIT, NASAPON |
|
dc.contributor.author |
PHRUTIVORAPONGKUL, AMPAI |
|
dc.contributor.author |
SUTTAJIT, MAITREE |
|
dc.contributor.author |
CHAIYASUT, CHAIYAVAT |
|
dc.contributor.author |
LEELAPORNPISID, PIMPORN |
|
dc.date.accessioned |
2022-11-30T09:29:55Z |
|
dc.date.available |
2022-11-30T09:29:55Z |
|
dc.date.issued |
2010-10-09 |
|
dc.identifier.citation |
Povichit, N., Phrutivorapongkul, A., Suttajit, M., Chaiyasut, C., & Leelapornpisid, P. (2010). Phenolic content and in vitro inhibitory effects on oxidation and protein glycation of some Thai medicinal plants. Pak J Pharm Sci, 23(4), 403-408. |
en_US |
dc.identifier.issn |
1011-601X |
|
dc.identifier.uri |
http://142.54.178.187:9060/xmlui/handle/123456789/14264 |
|
dc.description.abstract |
Fifteen medicinal plant extracts were investigated for: total phenolic content and free radical scavenging effect
by DPPH and ABTS assays; anti-lipid peroxidation activity by TBARS; and for antiglycation activity. The
results revealed that the total phenolic content showed good correlation with free radical scavenging by ABTS
(r = 0.721) and anti-lipid peroxidation by TBARS (r = -0.659), but showed no correlation with antiglycation.
Three extracts from Tamarindus indica, Camellia sinensis and Artocarpus lakoocha demonstrated a significant
antioxidant effect, and also showed a promising antiglycation effect. The IC50 (mg/ml) were 0.9-0.16 for the
DPPH method; TEAC values (mg Trolox/mg sample) of 1.72–2.83 for the ABTS method; IC50 (mg/ml) of 0.64-
1.22 for the TBARS method; and IC50 ranging from 0.01 to 3.20 for the antiglycation method. These three herbs were found to possess effective antioxidant and antiglycation activities, and could be further developed for use in anti-aging cosmetics. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi |
en_US |
dc.subject |
Antioxidant |
en_US |
dc.subject |
Glycation |
en_US |
dc.subject |
Lipid peroxidation |
en_US |
dc.subject |
Phenolic content |
en_US |
dc.title |
PHENOLIC CONTENT AND IN VITRO INHIBITORY EFFECTS ON OXIDATION AND PROTEIN GLYCATION OF SOME THAI MEDICINAL PLANTS |
en_US |
dc.type |
Article |
en_US |