• Anti-glycationand Anti-oxidation properties of Capsicum frutescens and Curcuma longa fruits: Possible role in prevention of diabetic complication 

  Ibrar Khan; Haroon Ahmad; Bashir Ahmad (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2014-09-20)

  The accumulation of advanced glycationend products (AGE’s) in the body, due to the non-enzymatic glycation of proteins is associated with several pathological conditions like aging and diabetes mellitus. Hence a plant ...
• Useful ethnophytomedicinal recipes of angiosperms used against diabetes in South East Asian Countries (India, Pakistan & Sri Lanka) 

  Marwat, Sarfaraz Khan; Fazal-ur-Rehman; Khan, Ejaz Ahmad; Khakwani, Abdul Aziz; Imdad Ullah; Khan, Kaleem Ullah; Khan, Inam Ullah (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2014-09-20)

  This paper is based on data recorded from various literatures pertaining to ethnophytomedicinal recipes used against diabetes in South East Asia (India, Pakistan and Srilanka). Traditional plant treatments have been ...
• Antidepressant activity of ethanolic extract of Hibiscus rosa sinenesis Linn. 

  Leena Khalid; Ghazala H Rizwani; Viqar Sultana; Hina Zahid; Raheela Khursheed; Huma Shareef (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2014-09-20)

  The present study was undertaken to assess the antidepressant effect of crude ethanolic extract of floral part of Hibiscusrosa sinensis (HRS) at doses 100mg/kg, 250mg/kg and 500mg/kg using three parameters which are forced ...
• Anti-nociceptive and anti-inflammatory activities of the extracts of Stauntonia chinensis 

  Chen Ying; Wu Ning; Liu Ying; Gao Hao; Jin, Dong Hua; Bin, Su Rui; Sheng, Yao Xin; Li Jin (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2014-09-20)

  The aim of this investigation was to study the anti-nociceptive and anti-inflammatory activities of Stauntonia chinensis (S. chinensis) and the possible action mechanisms of effective fractions. The anti-nociceptive and ...
• Comparative Pharmacognostic evaluation of some species of the genera Suaeda and Salsola leaf (Chenopodiaceae) 

  Uzma Munir; Anjum Perveen; Syeda Qamarunnisa (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2014-09-20)

  The genera Suaeda and Salsola are halophytic plants belong to the family Chenopodiaceae. Species of these genera have been extensively used in traditional medicines against many diseases due to their various bioactive ...
• Effect of deprotenizing agent and quantification of donepezil hydrochloride in human plasma 

  Liew, Kai Bin; Peh, Kok Khiang; Fung Tan, Yvonne Tze (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2014-09-20)

  The effect of deprotenizing agents on recovery of donepezil hydrochloride in the development of a simple, rapid, selective and sensitive high performance liquid chromatography method for quantification of donepezil hydrochloride ...
• Production and antioxidant properties of protein hydrolysate from Rastrelliger kanagurta (Indian mackerel) 

  Abdulazeez, Sheriff Sheik; Balasubramanian Sundaram; Baranitharan Ramamoorthy; Ponmurugan Ponnusamy (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2014-09-20)

  Fishery waste and by-products are valuable sources of raw material for recovery of antioxidant and bioactive peptides. Due to the increased demand for protein hydrolysates with antioxidative properties by various sectors ...
• Preparation, characterization and in vitro cytotoxicity assay of curcumin loaded solid lipid nanoparticle in IMR32 neuroblastoma cell line 

  Rahman, Mohamed Habibur; Muthiah Ramanathan; Veintramuthu Sankar (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2014-09-20)

  Curcumin (diferuloylmethane) possesses low bioavailability due to its poor solubility, permeability and rapid metabolism. Solid Lipid Nanoparticle of curcumin was prepared by high-speed homogenization technique. Stearic ...
• Preparation, characterization and in vitro cytotoxicity assay of curcumin loaded solid lipid nanoparticle in IMR32 neuroblastoma cell line 

  Rahman, Mohamed Habibur; Muthiah Ramanathan; Veintramuthu Sankar (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2014-09-20)

  Curcumin (diferuloylmethane) possesses low bioavailability due to its poor solubility, permeability and rapid metabolism. Solid Lipid Nanoparticle of curcumin was prepared by high-speed homogenization technique. Stearic ...
• Anti-inflammatory and anti-pyretic properties of Spirulina platensis and Spirulina lonar: A comparative study 

  Somchit, Muhammad Nazrul; Mohamed, Nor Azura; Zuraini Ahmad; Zakaria, Zainul Amiruddin; Lokman Shamsuddin; Omar Fauzee, Mohd Sofian; Kadir, Arifah Abdul (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2014-09-20)

  Spirulina spp. is a blue-green algae belongs to the family of Oscillatoriaceae, which having diverse biological activity. The aim of this current study was to evaluate and compare the anti-pyretic and anti-inflammatory ...
• Development of HPLC method by UV-VIS detection for the quantification of phenolic acids in different Ocimum sanctum Linn. extracts 

  Shafqatullah; Rasool Khan; Waseem Hassan; Arshad Hussain; Asadullah; Khaliq-ur-Rehman; Javid Ali (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2014-09-20)

  A simple and rapid chromatographic method has been developed for the simultaneous determination of five phenolic acids including Gallic acid, Chloroganic acid, Syringic acid, Benzoic acid and Vanillic acid by HPLC with ...
• Assessment of sex differences in Pharmacokinetics of carvedilol in human 

  Mateen Abbas; Khan, Abdul Muqeet; Sualeha Riffat; Tipu, Muhammad Yasin; Nawaz, Hafiz Awais; Muhammad Usman (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2014-09-20)

  Carvedilol is an anti-hypertensive agent capable of blocking both alph (α) and beta (β) receptors used to preclude cardiac arrhythmias and angina. The study was designed to evaluate the Pharmacokinetics of carvedilol in ...
• Evaluation of nutritional and sub-acute toxicological study of plant based supplement of Achyranthes aspera 

  Nudrat Fatima; Nabeela G Dar; Hina Imran; Tehmina Sohail; Uzma Asghar; Zahra Yaqeen; Shazia Syed; Khalid Jamil (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2014-09-20)

  The present study was conducted for the nutritional, microbiological and toxicological evaluation of test compound having main ingredient Achyranthes aspera. Nutritional value assessment, microbiological analysis and ...
• Enumeration of CD4+ CD25+ T regulatory cells in Type-II diabetes retinopathy 

  Nadeem Afzal; Khursheed Javaid; Shakeela Zaman; Abu Zafar; Abdul H Nagi (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2014-09-20)

  Diabetes mellitus (DM) is a health concern because it leads to complications such as retinopathy. Pakistan has 6.9 million DM affected people that will be doubled by 2025. A study was designed to enumerate CD4+ CD25+ ...
• Effects of intravenous bolus injection of emulsified isoflurane on QTc interval of healthy volunteers in Pharmacokinetics study 

  Rong Liu; Yan Li; Jin Liu; Zhang, Wen-Sheng; Yi, Xiao-Qian; Jing XU (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2014-09-20)

  Emulsified isoflurane is a novel intravenous anesthetic, which is a lipid emulsion of isoflurane. As some drugs have a QTc-prolongation effect which can increase a risk of arrhythmia, this study was to evaluate the effects ...
• Physicochemical and phytochemical standardization with HPTLC fingerprinting of Nigella sativa L. seeds 

  Aftab Ahmad; Asif Husain; Mohd. Mujeeb; Nasir Ali Siddiqui; Zoheir A Damanhour; Anil Bhandari (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2014-09-20)

  This study was designed to perform the physicochemical and phytochemical standardization with HPTLC fingerprinting of Nigella sativa seeds in order to establish the standard pharmacognostical parameters of this miracle ...
• Spectrophotometric method for the determination of Gemifloxacin mesylate in pure and tablet dosage form 

  Hassan, Syed Saeed Ul; Uzma Hayat; Imran Tariq; Irshad Ahmad; Hayat, Muhammad Munawar; Muhammad Uzair; Ansari, Muhammad Tayyab (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2014-09-20)

  A spectrophotometric method for the determination of Gemifloxacin mesylate (GFX) is developed and validated according to ICH guidelines. GFX is a fluoroquinolone that is used in the treatment of pneumonia. The analysis ...
• Green approach towards the determination of hydroxyzine dihydrochloride in pure and pharmaceutical dosage forms 

  Amina Mumtaz; Shahid Hussain; Muhammad Yasir (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2014-09-20)

  A simple eco-friendly method has been developed for detection of hydroxyzine dihydrochloride in pure and pharmaceutical dosage forms. Both conventional system and microwave assisted procedures are used for the development ...
• Anti-microbial screening of endophytic fungi from Hypericum perforatum Linn. 

  Huawei Zhang; Chen Ying; Yifei Tang (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2014-09-20)

  Anti-microbial properties of 21 endophytic fungal strains from Hypericum perforatum Linn. were evaluated against three human pathogens, Staphyloccocus aureus, Escherichia coli and Rhodotorula glutinis, and two phytopathogens, ...
• The effects of intellan and cytacon on hematological and biochemical parameter in rabbits: A comparative study 

  Humera Anser; Raheela Najam; Khan, Saira Saeed; Bushra Riaz; Sana Sarfaraz (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2014-09-20)

  Several plants have been selected based on their use in traditional systems of medicine, and research has identified a number of natural compounds that could act as Nootropicagents. In this study a herbal product Intellan ...

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