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Browsing Issue 01 by Issue Date

Browsing Issue 01 by Issue Date

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  • Effects of Cordyceps sinensis on macrophage function in high-fat diet fed rats and its anti-proliferative effects on IMR-32 human neuroblastoma cells 
    Dos Santos, Leandro Freire; Rubel, Rosalia; Bonatto, Sandro Jose Ribeiro; Yamaguchi, Adriana Aya; Torres, Maria Fernanda; Soccol, Vanete Thomaz; Da Silva, Andre Luís Lopes; Soccol, Carlos Ricardo (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    Macrophages have been considered an elusive yet emerging therapeutic target in tumor development since they are an important component in tumor microenvironment. The purpose of the present study was to evaluate the effect ...
  • Pharmacological validation of the folkloric uses of Cyperus rotundus L. in different ailments: An in vivo and in vitro research 
    Hussain, Musaddique; Waqas, Hafiz Muhammad; Hussain, Ikhlaq; Majeed, Abdul; Raza, Shahid Masood; Janbaz, Khalid Hussain (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    In vivo and in vitro research study was conducted on Cyperus rotundus to evaluate the sound mechanistic background in the treatment of gastrointestinal, bronchial and vascular disorders as well as in pain, emesis, pyrexia ...
  • Prescribing pattern of angiotensin receptor blocker: A study of errors and drug-drug interactions 
    Nesar, Shagufta; Shoaib, Muhammad Harris; Rafiq, Kiran; Rahim, Najia; Muhammad, Iyad Naeem; Iffat, Wajiha (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    Prescriptions comprising multi-drug therapy mostly illustrate the prescribing error. The phenomenon of error is bonded with human inaccuracy. The erroneous practice is observed in under developed countries like Pakistan, ...
  • Antifungal and cytotoxic activities of selected medicinal plants from Malaysia 
    Chan, Yik Sin; Cheah, Yit Hong; Chong, Poh Zen; Lai Khor, Hui; Siang Teh, Wen; Khoo, Kong Soo; Chooi Ong, Hean; Weng Sit, Nam (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    This study was conducted to investigate the antifungal potential and cytotoxicity of selected medicinal plants from Malaysia. The extracts from the stem of Cissus quadrangularis and the leaves of Asplenium nidus, Pereskia ...
  • Squid ink polysaccharide prevents chemotherapy induced injury in the testes of reproducing mice 
    Luo, Ping; Liu, Hua-Zhong; Yan Le, Xiao; Du, Hui; Kang, Xin-Huang (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    The present study was conducted to investigate the preventive effects of squid ink polysaccharides (SIP) on the damage of sperm and reproduction induced by cyclophosphamide that is most commonly used for treating clinically ...
  • A clinical study showing altered antioxidants profile in patients with hypertension 
    Khan, Abad; Iqbal, Zafar (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    We compared the plasma antioxidants level of normal control group with that of hypertensive patients in order to test the hypothesis “that antioxidants level has been diminished in hypertensive patients and that antioxidants ...
  • Synthesis, optimization and biological evaluation of 99mTc-digoxin as possible cardiac imaging agent 
    Bokhari, Tanveer Hussain; Roohi, Samina; Hina, Saira; Saeed, Shabana (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    Heart imaging radiopharmaceuticals could improve the diagnostic value of routine heart scanning for detecting cardiac disorders. The aim of the study was to prepare high radiochemical purity 99mTc-Digoxin in a yield of ...
  • A study of serological markers and lipid profile in non-alcoholic liver cirrhosis patients 
    Khan, Sadaf; Jamal, Siddiqua (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    Cirrhosis is the end result of chronic liver damage, associated with altered serum biomarkers and lipid profile. However, only few studies regarding serum biomarkers and plasma lipid profile in non-alcoholic liver cirrhosis ...
  • Evaluation of antioxidant and antimicrobial activities of Bergenia ciliata Sternb (Rhizome) crude extract and fractions 
    Khan, Aman; Jan, Gul; Danish, Muhammad (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    Biologically, screening of medicinal plants extracts have been since pre-historic to determine the antioxidants and antimicrobial profile. The present study was aimed to investigate and evaluate crude extract and different ...
  • Antiulcer activity of methanol-chloroform extract of Channa striatus fillet 
    Azemi, Ahmad Khusairi; Abd Rahim, Mohd Hafiz; Mamat, Siti Syariah; Mat Jais, Abdul Manan; Zakaria, Zainul Amiruddin (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    Channa striatus (Haruan) is Malaysian freshwater fish that is traditionally used to treat ailments related to wound and also ulcers. The aimed of the present study was to determine the mechanisms of anti-ulcer activity of ...
  • Palladium glutathione, N-acetylcysteine, D-penicillamine conjugation chemistry 
    Muhammad Mukhtiar; Syed Umer Jan; Khan, Muhammad Farid; Naseem Ullah; Abid Hussain; Saif ur Rehman; Qureshi, Muhammad Murtaza (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    The metalloelement Palladium has a number of potential Pharmaco-clinical advantages. Palladium compounds have antiviral, antibacterial, neuroprotective and antitumor properties. However studies have also indicated some ...
  • Rapid diagnostic method of tobacco products in saliva by fourier transform infrared spectroscopy (FTIR) 
    Channa, Naseem Aslam; Kalhoro, Dost Muhammad; Jahangir, Taj Muhammad (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    The present study was designed to explore the easy and fast method diagnosis of tobacco products in saliva of tobacco users (TU) by FTIR. Sixty four male tobacco users (TU) with mean age range 15.3 to 30.7 years were ...
  • Safety of fenbendazole in common peafowl (Pavo cristatus) 
    Seema Abbas Sajid Umar; Khan, Muhammad Irfan; Qamar-un-Nisa; Muhammad Younus; Kiran Aqil; Rizwan Qayyum; Muhammad Yaqoob; Asif Ali; Yaseen, Muhammad Asif; Shah, Muhammad Ali (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    The present study was undertaken to find out the safety levels of fenbendazole in common peafowl. This bird, raised on aviaries and zoos, can be severely parasitized with Ascaridia galli (enteric worms) and Syngamus trachea ...
  • Effects of gamma irradiation on the physico-chemical and biological properties of levofloxacin 
    Saleem Raza; Yousaf Iqbal; Ihsan Ullah; Mubarak, Mohammad S; Hameed, Muhammad Usman; Muslim Raza (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    The aim of the present study was to examine the effect of gamma radiation on levofloxacin. Powder form of levofloxacin was subjected to different radiation doses (25, 50, 75, 100 and 125kGy) of Cobalt-60 source in ...
  • Phytochemical screening and antibacterial activity of Cyclamen persicum Mill tuber extracts 
    Raed Alkowni, Shehdeh Jodeh; Fatima Hussein, Nidal Jaradat (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    The emerging drug resistance bacteria increased the demand on the discovery of antibiotics from natural sources. This research was aimed to study the antibacterial reactivity; as well as the phytochemicals, of the wild ...
  • Phytochemical screening and antibacterial activity of different solvent extracted samples of Arisaema jacquemontii 
    Iqbal, Madiha; Bakht, Jehan; Shafi, Muhammad (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    The current research was carried out to assess the antibacterial activities and phytochemical analysis of the methanol, n-hexane, ethyl acetate, n-butanol soluble fractions and aqueous extracts of the tubers of Arisaema ...
  • Toxic effect of common poisonous plants of district Bannu, Khyber Pakhtunkhwa, Pakistan 
    Khan, Rehman Ullah; Mehmood, Sultan; Khan, Saad Ullah (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    The present paper was a part of Ph.D research work, conducted during the year 2014, in which 87 poisonous plants belonging to 54 genera, were collected, documented and preserved in the herbarium of Bannu, Department of ...
  • Estimation of simvastatin and cetirizine by RP-LC method: Application to freeze and thaw (FT) stability studies 
    Naveed, Safila; Khan, Usman Ghani; Aisha Sana; Huma Ali; Farya Zafar; Fatima Qamar; Ghulam Sarwer; Sarah Abbas; Alam, M Tanweer; Shinwari, Muhammad Ibrar (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    Sensitive, simple, reliable and rapid HPLC technique for the estimation of simvastatin (SMV) and cetirizine has been designed in this study. The chromatographic conditions were set using Shimadzu LC-10 AT VP pump, with UV ...
  • In vitro Salmonella typhi biofilm formation on gallstones and its disruption by Manuka honey 
    Abdul Hannan; Bajwa, Asma Ejaz; Saira Riaz; Usman Arshad; Sidrah Saleem; Bajwa, Usama Ijaz (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    Biofilm is a complex community of single or different types of microorganisms (bacteria, viruses, fungi, protozoa) attached to a surface and stick to each other through production of extracellular matrix. Salmonella typhi ...
  • Disposition kinetics of omeprazole in healthy female volunteers in Pakistan 
    Sadia Ashraf; Tanweer Khaliq; Ijaz Javed; Bilal Aslam; Nazia Qadir; Nadia Noor (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-01-20)
    Omeprazole (OMP) a proton pump inhibitor is widely used to suppress gastric acid secretions of parietal cells of stomach and metabolized predominantly by CYP2C19. The objective of the present study was to investigate the ...

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