• REPORT Susceptibility of avian pathogenic Escherichia coli from Zoo birds in Indonesia to antibiotics and disinfectants 

  Sajid Umar, Sajid Umar; Ana Triana Maiyah, Ana Triana Maiyah; Mehwish Shareef, Mehwish Shareef; Hajra Qadir, Hajra Qadir; Qamar-un-Nisa, Qamar-un-Nisa; Seema Abbas, Seema Abbas (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-04-02)

  Antibiotic resistance in avian pathogenic Escherichia coli (APEC) is a common problem in the Indonesian poultry industry. Zoo birds have been postulated as sentinels, reservoirs, and potential spreaders of antibiotic ...
• SHORT COMMUNICATION Synthesis of drug metal complexes and their influence on human platelet aggregation 

  Mansoor Ahmed, Mansoor Ahmed; Mohsin Ali, Mohsin Ali; Ayatollahi, Seyed Abdulmajid; Marjan Esfahanizadeh, Marjan Esfahanizadeh; Farzad Kobarfard, Farzad Kobarfard; Ameer Hasan, Ameer Hasan; Khan, Khalid Mohammed; Syed Moazzam Haider, Syed Moazzam Haider (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-04-01)

  During the past few decades the emergence of inorganic medicinal chemistry has been developed novel therapeutic agents. Researcher's perseverance in this branch of chemistry has led them to explore further valuable chemical ...
• Analgesic and anti-inflammatory activities of fixed oil of Macrotyloma uniflorum (Lam.) Verdc. in mice and rats 

  Syeda Anum Fatima, Syeda Anum Fatima; Baig, Sadia Ghousia; Muhammad Mohtasheem ul Hasan, Muhammad Mohtasheem ul Hasan; Salman Ahmed, Salman Ahmed; Salma, Salma (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-03-31)

  Macrotyloma uniflorum commonly known as horse gram or kulthi bean is grown as a pulse for livestock and human consumption. The beans contain about 1.3% fat, 18% protein, 15% carbohydrate along with vitamins and minerals. ...
• Evaluation of phytochemical and in vitro antioxidant activity of water and acetone extracts of selected vegetables 

  Faria Nisar, Faria Nisar; Mirza, Muhammad Aslam; Malik, Riffat Naseem; Ch, Muhammad Aziz; Kauser Yasmeen, Kauser Yasmeen (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-03-30)

  The aim of this study was to determine antioxidant activity of Brassica oleracea (Cabbage), Brassica rapa (Turnip) and Raphanus sativus (Radish). All of the three selected vegetables were ultrasonically extracted in water ...
• Pharmacophoric screening of newly synthesized isoniazid derivatives and their antimycobacterial activity 

  Sabahat Naeem, Sabahat Naeem; Shamim Akhtar, Shamim Akhtar; Zaheer Ali, Zaheer Ali; Muhammad Yahya Noori, Muhammad Yahya Noori; Ahsaan Ahmed, Ahsaan Ahmed (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-03-29)

  Mycobacterium tuberculosis is clinically recognized as a causative agent of Tuberculosis. Keeping in view, this study was endeavored to screen our previously synthesized seventeen INH analogues for their antimycobacterial ...
• Free radical scavenging activity of Telfairia occidentalis extracts and their effects on iron-sulphate induced lipid per oxidation 

  Temitope, Adedosu Olaniyi; Emmanuel, Adeleke Gbadebo; Akintola, Adebola Olayemi; Olabode, Fatoki John; Isaac, Adelusi Temitope (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-03-28)

  Non-enzymic natural antioxidants of plant origin are known to play a key role in inflammation linked with free radicals and oxidative stress. This study investigates the free radical scavenging activity of various Telfairia ...
• Analgesic, anti-inflammatory and diuretic activities of Cicer arietinum L. 

  Darakhshan Masroor, Darakhshan Masroor; Baig, Sadia Ghousia; Salman Ahmed, Salman Ahmed; Syed Muzzammil Ahmad, Syed Muzzammil Ahmad; Muhammad Mohtasheem ul Hasan, Muhammad Mohtasheem ul Hasan (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-03-27)

  Analgesic, anti-inflammatory and diuretic activities of the methanol extract of two varieties of Cicer arietinum viz black or Desi and white or Kabuli were tested in the doses of 200 and 400 mg/kg. For analgesic effect ...
• Effects of Qibaipingfei capsules on pulmonary vascular relaxation through KATP channel activation by the NO/cGMP signaling pathway 

  Zhu, Jie; Wang, Baoqin; Lu, Mei; Tong, Jiabing; Yang, Jiabing; Li, Zegeng (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-03-26)

  This research explores the effects of Qibaipingfei (QBPF) capsules on pulmonary vascular relaxation in vitro and the relationship of the ATP-sensitive K+ (KATP) channel and nitric oxide (NO) pathway. Vasodilator effects ...
• Assessment of children immunization pattern in Children Hospital Lahore, Pakistan 

  Kalsoom Tariq, Kalsoom Tariq; Rukiya Tariq, Rukiya Tariq (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-03-25)

  The basic aim is to assess immunization pattern of children up to 15 months of age. A cross-sectional study was conducted on 100 immunized children in Children hospital Lahore, Pakistan. Single dose 0.05ml to 0.1ml of BCG ...
• The genetic and chemical diversity in three original plants of licorice, Glycyrriza uralensis Fisch., Glycyrrhiza inflata Bat. and Glycyrrhiza glabra L. 

  Yang, Rui; Yuan, Bochuan; Ren, Guangxi; Wang, Liqiang; Cheng, Ting; Liu, Ying (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-03-24)

  Licorice is one of the most frequently used Chinese herbs, mainly containing triterpenoids and flavonoids. Three original plants, Glycyrrhiza glabra L., Glycyrrhiza uralensis Fisch., and Glycyrrhiza inflata Bat., are ...
• Labeling of epirubicin with technetium-99m: Optimization, biodistribution and scintigraphic imaging in tumor bearing mice 

  Saira Hina, Saira Hina; Bokhari, Tanveer Hussain; Samina Roohi, Samina Roohi; Rajoka, Muhammad Ibrahim; Muhammad Sohaib, Muhammad Sohaib (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-03-23)

  Epirubicin is an antineoplastic agent of anthracycline antibiotic, used for treating a variety of tumor types such as lymphoma, cancer of the breast, lung, ovary and stomach. The objective of this work was to demonstrate ...
• Potential action of Rumex vesicarius (L.) against potassium dichromate and gentamicin induced nephrotoxicity in experimental rats 

  Subramaniyan, Vetriselvan; Shaik, Summaiya; Bag, Anupam; Manavalan, Gobinath; Chandiran, Sarath (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-03-22)

  To determine the ameliorative potential of the active fraction from different extracts of Rumex vesicarius against potassium dichromate and gentamicin induced nephrotoxicity in experimental rats and its possible mechanism ...
• Phytochemical screening and antibacterial potential of Artemisia absinthium L., Swertia chirayita and Sphaeranthus indicus 

  Dilshad, Rimsha; Batool, Rida; Jamil, Nazia (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-03-21)

  Utilization of herbs for medicinal purpose started in the early history of mankind several thousand years ago. In this study, some plants that are used for lowering cholesterol level in local areas of Pakistan, such as ...
• Synergistic potential of Zingiber officinale and Curcuma longa to ameliorate diabetic-dyslipidemia 

  Hussain, Naveed; Hashmi, Abu Saeed; Wasim, Muhammad; Akhtar, Tauqeer; Saeed, Shagufta; Ahmad, Toheed (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-03-20)

  To find the cure of world’s one of the leading morbid and mortal disorders; diabetes mellitus and its most prevalent complication, ‘diabetic-dyslipidemia’, is one of the leading health challenges of 21st century. The use ...
• Drug-target network of taxanes revealed by data mining 

  Chen, Shao-Jun; Wei-Cai, Wei-Cai; Li, Zhao-Hui (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-03-19)

  Taxanes, mainly group paclitaxel and docetaxel, are amongst the most promising anticancer agents that are widely used for a variety of tumor types. It is a great challenge to gain a quick overview of the molecular mechanisms ...
• Assessment of environmental impact on physico-chemical parameters and heavy metals content of bovine milk available in Malir District 

  Parween, Rubina; Nazim, Kanwal; Ara, Darakhshan; Kishwer, Farah; Shaukat, Shahid (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-03-18)

  This work designed to investigate the physico-chemical properties (pH, conductivity, salinity, TDS, DO and specific gravity) and level of essential heavy metals (Fe, Cu and Zn) and deleterious metal (Cd) were analyzed in ...
• Cyclic voltammetric studies of Gemifloxacin using Gold electrode in presence of Britton-Robinson Buffer 

  Ali, S Azhar; Hassan, Atya; Muhammad, Mahboob (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-03-17)

  The electrochemical study of the Gemifloxacin has been conducted using cyclic voltammetry technique at gold electrode. Gemifloxacin is antibacterial compound. In present study the electrochemical parameters of Gemifloxacin ...
• Comparison efficacy of Curosurf and Survanta in preterm infants with respiratory distress syndrome 

  Mirzarahimi, Mehrdad; Barak, Manouchehr (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-03-16)

  This study aim was to compare the therapeutic efficacy of Curosurf and Survanta in preterm infants which were admitted into NICU. In this interventional study, 150 preterm infants divided randomly in two groups (75 in ...
• Alpha-tocopherol ameliorates nephrotoxicity associated with the use of colistin in rabbits 

  Bader, Zarafshan; Waheed, Akbar; Bakhtiar, Salman; Khan, Imrana Maqsood (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-03-15)

  The alarming rise in the rate of multi drug resistant, life threatening gram negative infections has brought renaissance in the use of Colistin for last two decades. The major constraint in its utilization is its ...
• Formulation and in vitro evaluation of directly compressed controlled release tablets designed from the Co-precipitates 

  Khan, Kamran Ahmad; Khan, Gul Majid; Jan, Syed Umer; Ur-Rehman, Asim; Mehsud, Saifullah (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 2018-03-14)

  Controlled release dosage forms provide sustained therapeutics effects for prolonged period of time and improve patient compliance. In present study, controlled release co-precipitates of Metoprolol Tartrate and Losartan ...

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