• A mini-review of therapeutic potential of Mangifera indica L. 

  Nazima Batool; Noshin Ilyas; Sumera Shabir; Maimoona Saeed; Roomina Mazhar; Amjid, Muhammad Waqas (Karachi: Pakistan Botanical Society, University of Karachi, 2018-07-20)

  Among known species of 69 Mangifera, Mangifera indica L. is a medicinal plant being used in tropical regions by indigenous people. It has been a main plant species being used in Ayurvedic as well as indigenous medical ...
• Immunological study of different fraction of wheat proteins 

  Shaista Khan; Khaskheli, Muhammad Hassan; Ghulam Nabi; Deverajani, Bikha Ram; Naima Memon; Shar, Ghulam Abbas (Karachi: Pakistan Botanical Society, University of Karachi, 2018-07-20)

  Wheat allergy specifically refers to the adverse reaction involving IgE antibody to one or more protein fraction of wheat such as albumin, globulin, gliadin and glutenin (gluten). The majority of IgE-mediated reactions ...
• Role of prostaglandin H synthase in activation of acrylonitrile to cyanide 

  Abbasi-Al, Ahmed Fahad; Esmat Ahmed; Mohamadin, Mohamed Ahmed; Abdel Naim, Ashraf Bahyeldeen (Karachi: Pakistan Botanical Society, University of Karachi, 2018-07-20)

  The present study aimed at investigating the in-vitro oxidation of acrylonitrile (ACN) to cyanide (CN−) by prostaglandin H synthase (PHS). Detection of CN− is considered a marker for free radical intermediates involved in ...
• Antioxidant, cytotoxicity, protein kinase inhibition and antibacterial activities of Fragaria × ananassa leaves 

  Ihsan Khan; Saira Tabassum; Tofeeq-ur-Rehman; Muhammad Ikram; Ihsan ul Haq; Muhammad Zia (Karachi: Pakistan Botanical Society, University of Karachi, 2018-07-20)

  Fragaria × ananassa leaves extracts prepared in different solvents were subject for antioxidative, cytotoxicity, protein kinase inhibition and antibacterial activities. The extracts showed varying activities depending upon ...
• Ethanolic Ficus carica leaf extract supplementation affects the behavior of male albino mice 

  Maryam Ashfaq; Shahid Iqbal; Gillani, Qurat Ul Ane; Furhan Iqbal (Karachi: Pakistan Botanical Society, University of Karachi, 2018-07-20)

  Ficus carica has been known for its medicinal benefits for the treatment of metabolic, cardiovascular and respiratory problems but little information is available regarding the effects of its leaf extracts on behavior. ...
• Estimation of trace elements and in vitro biological activities of lichens extracts 

  Shahida Rehman; Saiqa Andleeb; Niazi, Abdul Rehman; Shaukat Ali (Karachi: Pakistan Botanical Society, University of Karachi, 2018-07-20)

  Infectious diseases caused by etiological agents are still a major threat to public health. Their impact is particularly large in developing countries due to relative unavailability of medicine and the emergence of widespread ...
• Antimicrobial and antiurease potential of Diorganotin(IV) Schiff bases 

  Khan, Shuja Abbas; Rehan Naeem; Shah Hussain; Saqib Ali; Naveed Muhammad; Zahid Hussain; Shaukat Shujah (Karachi: Pakistan Botanical Society, University of Karachi, 2018-07-20)

  Six new diorganotin (IV) Schiff bases, [(CH3)2SnL] (I), [(C2H5)2SnL] (II), [(n-C4H9)2SnL] (III), [(C6H5)2SnL] (IV), [(CH2C6H5)2SnL] (V) and [(n-C8H17)2SnL] (VI) where L = N-(5-bromo-2-oxidobenzylidene)phenylacetohydrazide, ...
• A facile method for the synthesis of 2-(3-hydroxy-1-adamantyl)-2oxoacetic acid and it’s optimization 

  Wang, Hui-fei; Run Gan; Jing Zhou; Qi Liao; Wang, Tian-bao; Zhong, Cai-ling; Xiang, Yuan-yuan; Lin, Hong-bo; Hu, Xiang-nan (Karachi: Pakistan Botanical Society, University of Karachi, 2018-07-20)

  2-(3-hydroxy-1-adamantyl)-2-oxoacetic acid (IV), a key intermediate of saxagliptin for type 2 diabetes mellitus (T2DM), was prepared from 1-adamantanecarboxylic acid(I) via oxidation by potassium permanganate(KMnO4) to ...
• Development and evaluation of eudragit based microparticles of dexibuprofen for site specific drug release 

  Qandeel Khalid; Mahmood Ahmad; Minhas, Muhammad Usman; Haroon Rashid (Karachi: Pakistan Botanical Society, University of Karachi, 2018-07-20)

  The main purpose of work was to formulate dexibuprofen loaded eudragit L-100 micro particles to acquire site specific delivery of dexibuprofen. Micro particles were formulated by an emulsion solvent evaporation method. ...
• Phenotypic expression and prevalence of multi drug resistant extended spectrum beta-lactamase producing Escherichia coli and Klebsiella pneumoniae in Karachi, Pakistan 

  Sakina Fatima; Muhammad, Iyad Naeem; Khan, Muhammad Naseem; Subia Jamil (Karachi: Pakistan Botanical Society, University of Karachi, 2018-07-20)

  The aim of the present study was to evaluate the prevalence rate of ESBL producing Gram negative isolates of E. coli, K. pneumoniae and P. mirabilis, to determine the association of various factors with ESBL production and ...
• Therapeutic effects of targeted nursing interventions combined with auricular-plaster therapy on anxiety level and life quality of Hepatitis B patients 

  Jiao Yu; Yuguo Yu (Karachi: Pakistan Botanical Society, University of Karachi, 2018-07-20)

  Mood disorders are common problems in patients with chronic hepatitis B virus (HBV) infection, most clinical treatment focus on anti-viral and anti-fibrosis rather than taking care of mood disorders. In the past decades, ...
• Comparative pharmacokinetics of Omeprazole and its metabolites in poor and extensive metabolizer Pakistani healthy volunteers and a review of different studies 

  Lateef Ahmad; Zafar Iqbal; Yasar Shah; Shabnam Nazir; Abad Khan; Khan, Muhammad Imran; Abbas Khan; Fazli Khuda; Ismail Khan (Karachi: Pakistan Botanical Society, University of Karachi, 2018-07-20)

  This study was designed to evaluate a comparative single dose (40mg) pharmacokinetics (PK) of Omeprazole (OMP) and its two metabolites, 5-hydroxy Omeprazole (5-OH-OMP) and Omeprazole sulphone (OMP-S) in poor (PM) and ...
• Wound healing effect of ethanolic extract from Morning Glory (Ipomoea carnea Jacq.) leaves by using different models in rats 

  Rajesh Shukla; Gaurav Gupta; Sushil K Kashaw; Alok Pal Jain; Santram Lodhi (Karachi: Pakistan Botanical Society, University of Karachi, 2018-07-20)

  Current study aims to evaluate the wound healing effect with apparent mechanism and determination of flavonoid (quercetin) from ethanol extract of Ipomea carnea jacq. leaves, family Convolvulaceae. The wound healing effect ...
• Isolation of flavonoides from Artemisia macrocephala anticholinesterase activity: Isolation, characterization and its in vitro anticholinesterse activity supported by molecular docking 

  Mohammad Shoaib; Ismail Shah; Achyut Adikhari; Niaz Ali; Tahir Ayub; Zaheer Ul-Haq; Shah, Syed Wadood Ali (Karachi: Pakistan Botanical Society, University of Karachi, 2018-07-20)

  : In this study the flavonoids isolated from Artemisia macrocephala were screened out for anticholinesterase activity. The isolated flvanoids were characterized by HNMR, NOESY, COSY, HMBC, HSQC and mass spectroscopy. The ...
• Antihyperlipidemic and anti-hyperglycemic effects of Cymbopogon jwarancusa in high-fat high-sugar diet model 

  Khan, Sarah Jameel; Syeda Afroz; Khan, Rafeeq Alam (Karachi: Pakistan Botanical Society, University of Karachi, 2018-07-20)

  Hyperlipidemia is the root cause for development of atherosclerosis, coronary heart disease, diabetes mellitus, obesity, hypertension and cerebral palsy. Cymbopogon jwarancusa is an aromatic grass (Rusha grass, khavi grass) ...
• Antioxidant and xanthine oxidase inhibitory activity of Eucommia ulmoides Oliver leaf extracts 

  Guiming Fu; Huoyan Tong; Hailong Zeng; Bin Zou; Jianxin Chai; Lunning Zhang; Mingyong Xie; Feng Chen; Yin Wan (Karachi: Pakistan Botanical Society, University of Karachi, 2018-07-20)

  The total phenolic content, flavonoid content, in vitro xanthine oxidase (XOD) inhibitory activity and antioxidant activity (AA) of Eucommia ulmoides Oliver leaf extracts were investigated. The AA investigations included ...
• Role of chemical and herbal dentifrices against indigenous oral pathogens 

  Shafiq, Humerah Bano; Sunil Nawaz; Uzma Amin; Rasool, Muhammad Hidayat (Karachi: Pakistan Botanical Society, University of Karachi, 2018-07-20)

  The oral cavity has its own significant micro-flora but under unhygienic conditions can cause infections or diseases like gingivitis, caries, plaque and gum bleeding. Out of more than 700 oral microbial species, some ...
• Antibacterial assay and reversion of carbon tetrachloride induced liver damage on wistar mice by Vernonia amygdalina. Delile 

  Chukwuemeka, Nwinyi Obinna; Oyebisi, Smith Oluwakemi; Adebisi Oluwadare, Olugbuyiro Joseph; Oladapo, Rotimi Solomon; Berka, Njobeh Patrick (Karachi: Pakistan Botanical Society, University of Karachi, 2018-07-20)

  In this study Vernonia amygdalina. Delile stem and leaves were evaluated for anti-cancer and antibacterial actions against selected microorganisms. The crude plant extracts were extracted using methanol and fractionated ...
• Rat as an animal model for studying glutaredoxin-5 gene 

  Ateeq Ashraf; Najeeb Ullah; Ghayyor Ahmad (Karachi: Pakistan Botanical Society, University of Karachi, 2018-07-20)

  Glutaredoxin-5 (Grx5) is a mitochondrial monothiol, participating in iron-sulfur clusters’ biogenesis. It directly maintains normal cytosolic and mitochondrial iron homeostasis, participates in erythropoiesis and oxidative ...
• Antidiarrhoeal effects of the methanol extract of the aerial parts of Mitracarpus villosus 

  John-Africa, Lucy Binda (Karachi: Pakistan Botanical Society, University of Karachi, 2018-07-20)

  Mitracarpus villosus (S.W) DC is used as treatment for diarrhoea and dysentery in some communities of West Africa. This study aimed to investigate the antidiarrhoeal effects of the methanol extract of the aerial parts of ...

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