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EFFECT OF ALUMINIUM METAL ON GLUTATHIONE (GSH) LEVEL IN PLASMA AND CYTOSOLIC FRACTION OF HUMAN BLOOD

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dc.contributor.author KHAN, HAROON
dc.contributor.author KHAN, M.FARID
dc.contributor.author JAN, SYED UMER
dc.contributor.author ULLAH, NASEEM
dc.date.accessioned 2022-12-01T05:10:37Z
dc.date.available 2022-12-01T05:10:37Z
dc.date.issued 2011-01-03
dc.identifier.citation Khan, H., Khan, M. F., Jan, S. U., & Ullah, N. (2011). Effect of aluminium metal on glutathione (GSH) level in plasma and cytosolic fraction of human blood. Pak J Pharm Sci, 24(1), 13-18. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/14329
dc.description.abstract Aluminium is being used in the medicines in the form of antacids. The Aluminium metal can be leached from our utensils and can harm the body for its side effects, if become available to the systemic circulation. So it is important to check the effect of Aluminum on the Glutathione in vivo condition. Ellman method was used to determine the effect of Aluminum on GSH level in whole blood spectrophotometerically. 5,5-Dithiobis, 2- Nitrobenzoic Acid, Glutathione, Aluminium sulphate, phosphate buffer, HCl (Hydrochloric acid) and other laboratory instruments were used to conduct the research work. Time dependent effect of Aluminum on Glutathione level in whole blood was also checked and decrease was observed. This study also shows the effect of Aluminum as helping agent for the Glutathione to enhance the antioxidant system of the body or a cause for depletion of reduced Glutathione. en_US
dc.language.iso en en_US
dc.publisher Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi en_US
dc.subject Aluminium (Al) en_US
dc.subject Glutathione (GSH) en_US
dc.subject Whole blood en_US
dc.subject Ellman’s method, 5, 5-Dithiobis en_US
dc.subject 2-Nitrobenzoic Acid (DTNB). en_US
dc.title EFFECT OF ALUMINIUM METAL ON GLUTATHIONE (GSH) LEVEL IN PLASMA AND CYTOSOLIC FRACTION OF HUMAN BLOOD en_US
dc.type Article en_US


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