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Browsing Issues No. 6 (Special) by Issue Date

Browsing Issues No. 6 (Special) by Issue Date

Now showing items 1-20 of 30

Application of antibiotic impregnated beads on the patients with tibial chronic osteomyelitis

Sun, Pei-qiang; Ma, Young; Zhang, Yong-chun; Cheng, Ming-Guo (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-11-20)

To investigate the clinical efficacy of antibiotic impregnated beads on the tibial chronic osteomyelitis, so as to search for a more applicable method for the treatment. Through comparative analysis, we divided 72 patients ...
Effect and mechanism of hyaluronic acid on the neurotoxic injury of lidocaine

Cai, Junying; Lu, Jun; Ju, Youting; Zhou, Bin; Xiao, Fan; Luo, Zhenzhong (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-11-20)

Hyaluronic acid (HA) is used to aid tissue repair and is a characterized inhibitor of TRPV1 channels. In this study, we investigated the effects of HA on lidocaine induced neurotoxicity and its mechanism of action. U87-MG ...
Inhibitory effect of Saposhnikovia divaricate polysaccharide on fibroblast-like synoviocytes from rheumatoid arthritis rat in vitro

Ci, Binbin; Wang, Wenjun; Ni, Yongan (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-11-20)

To study the mechanism and inhibitory effect of Saposhnikovia divaricata polysaccharide (SDP) on fibroblast-like synoviocytes (FLS) isolated from rheumatoid arthritis rat model. Rheumatoid arthritis rat model was established ...
Effect of muscarinic receptors agonist in the rat model of coronary heart disease: A potential therapeutic target in cardiovascular diseases

Zhang, Hongli; Peng, Lirong; Zhou, Kai; Zheng, Nanbo; Yan, Kangkang (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-11-20)

Cardiac hypertrophy is a one of common type of CHD, responsible for cardiac mortality worldwide. The present study designed to investigate the effect of muscarinic receptors agonist in the rat model of cardiac hypertrophy. ...
Effect of acetylcholine in rat brain in promoting early recovery of spinal cord injury by inhibiting monoamine oxidase enzyme: Preclinical evidence

Chen, Cheng; He, Lin-fei; Zhang, Jia-nan; Zhang, Yi (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-11-20)

Spinal cord injury (SCI) is one of the most common causes of severe incapacity and has been associated with high health care expenditures. The present study designed to assess the effect of acetylcholine in rat brain ...
Effect of lamotrigine on cognitive function and serum inflammatory factors in patients with depression of recurrent bipolar disorder

Shi, Shaobo; Li, Lu; Song, Lina; Wang, Xinrui (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-11-20)

In the present study, an effort was made to investigate the effect of lamotrigine on cognitive function and serum inflammatory factors in patients with depression of recurrent bipolar disorder and to explore its possible ...
The effects of carboplatin and etoposide on advanced small cell lung cancer and serum tumor markers in correlation with long-term survival rate

Ye, Qing; Lin, Jian; Feng, Jiaxi (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-11-20)

Objective of the present study was to analyze the efficacy of recombinant human endo-statin combined with carboplatin and etoposide regimen (CE regimen) in treatment of patients with advanced small cell lung cancer and its ...
Application of controlled hypotension in cesarean section of pregnant women with high-risk hemorrhage

Meng, Fanqing; Chang, Zhaohua; An, Shizhi; Liu, Wei; Qi, Haiyan; Fang, Yong; Li, Liang (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-11-20)

To explore the application of controlled hypotension in cesarean section of pregnant women with high-risk hemorrhage. 75 cases were randomly divided into three groups: controlled hypotension Group 1 (Group H1), ...
Compound shuanghua tablets combined with Western medicine on serum and secretion inflammatory factors in patients with acute secretory otitis media caused by swimming

Zhang, Wenbo (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-11-20)

To observe and analyze the effect of compound shuanghua tablets combined with western medicine on serum and secretion inflammatory factors in patients with acute secretory otitis media caused by swimming. The 140 patients ...
Sedative effect of dexmedetomidine in spinal-epidural anesthesia on hysteromyomectomy

Liu, Xin-Fa; Gao, Yong-Tao (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-11-20)

To investigate the sedative effect of dexmedetomidine in spinal-epidural anesthesia on hysteromyomectomy a total of 100 hysteromyomectomy patients were randomly divided into the control group and the observation group with ...
Clinical observation of the efficacy of low-molecular-weight heparin calcium in prophylaxis of the deep venous thrombosis following the gynecological tumor surgery

Wei, Na; Qi, Yani; Yang, Haiyan; Guo, Lixin (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-11-20)

Present study is conducted to investigate the efficacy and safety of application of low-molecular-weight heparin calcium in the prophylaxis of deep venous thrombosis (DVT) following the laparoscopic surgery for gynecological ...
The effects of VEGF on deep venous thrombosis in the perioperative period of elderly fracture patients

Wang, Yingliang; Zheng, Guanzhong; Meng, Xianhao; Wang, Binshuai (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-11-20)

Deep venous thrombosis is a very common complication of orthopedic patients on bed rest. In the present study, comparison of the correlation between serum vascular endothelial growth factor (VEGF) with D-Dimer, fibrinogen ...
Effect of donepezil hydrochloride & aerobic exercise training on learning and memory and its mechanism of action in an Alzheimer's disease rat model

Jiangbo, Nan; Liyun, Zhang (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-11-20)

This study was designed to explore the combined effect of donepezil hydrochloride and aerobic exercise training on learning and memory and to check its mechanism of action in an Alzheimer's disease (AD). Thirty rats were ...
Preoperative antiplatelet drugs on the hemorrhage and allogenic blood transfusion condition after coronary artery bypass graft surgery

Zhu, Pengchong; Chen, Ying; Wang, Honglu; Song, Bing (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-11-20)

Aim of the study was to observe and evaluate the postoperative hemorrhage and allogenic blood transfusion condition in patients who were exposed to different levels of clopidogrel and aspirin beforeon-pump coronary artery ...
Effect of propofol and sevoflurane on cognitive function among elderly patients undergoing elective surgery under anesthesia

Chen, Xin-de; Xie, Wei; Zhou, Qing-he (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-11-20)

The objective of present study was to compare the effect of propofol and sevoflurane on cognitive function among elderly patients undergoing elective surgery under anesthesia. Elderly patient who met eligibility criteria ...
Clinical observation on tranexamic acid combined with reduced glutathione for the treatment of chloasma

Feng, Chao; Yan, Min (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-11-20)

To observe and analyze the efficacy of tranexamic acid combined with reduced glutathione in chloasma treatment. The 180 patients diagnosed with chloasma and treated in our hospital from June 2015 to March 2018 were enrolled ...
Enhancement of Anterior cruciate ligament injury repairing using connective tissue growth factor in a rabbit model

Sun, Peiqiang; Chen, Shuangcheng; Liu, Luyong; Gao, Xiang (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-11-20)

The study was to evaluate the contribution of connective tissue growth factor (CTGF) to the regeneration of the torn anterior cruciate ligament (ACL) in a rabbit. ACL transection surgeries were performed on both knees of ...
Analysis of the advantages and disadvantages in application of oxygendriven aerosol and aerosol inhalation by air compressor for the pediatric asthma

Wang, Xiaoling; Wang, Jiangtao (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-11-20)

Present study is done to analyze the advantages and disadvantages in application of oxygen-driven aerosol and aerosol inhalation by air compressor for the pediatric asthma. A total of 180 patients with pediatric bronchial ...
Clinical application and effect of dexmedetomidine in combination with continuous positive airway pressure on one-lung ventilation in lung surgery of elder patients

Lin, Jian; Li, Jia-bin; Lu, Zhiwei (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-11-20)

In this study, 126 elder patients who underwent thoracic surgery under general anesthesia were divided into three groups randomly, i.e. dexmedetomidine group, positive ventilation group and combination group. All patients ...
A clinical study on the combined therapy of methotrexate and immuno adsorption in the treatment of rheumatoid arthritis disease

Zhao, Liming; Nie, Wenbo; Li, Bin; Zhang, Chengdong; Ye, Fagang (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2018-11-20)

Objective of the present work was to study the effect and significance of the combined therapy of methotrexate and immune adsorption in the treatment of rheumatoid arthritis disease. 56 patients with rheumatoid arthritis ...

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