• Analysis of the effect of methyl 2-acetamide-3-methylquinoxaline-7- carboxylate 1,4-di-N-oxide on the relative expression of the trypanothione reductase gene in Trypanosoma cruzi epimastigotes 

  Vazquez-Jimenez, Lenci K; Hernandez-Posada, María I; Paz-Gonzalez, Alma D; Nogueda-Torres, Benjamín; Martinez-Vazquez, Ana V; Herrera-Mayorga, Veronica; Bocanegra-Garcia, Virgilio; Rivera, Gildardo (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2019-05-27)

  In recent decades, some quinoxaline 1,4-di-N-oxide derivatives have been shown to have better trypanocidal activity than the reference drugs; however, their mechanism of action is not yet clear, although it is suggested ...
• Effect of peripherally inserted central catheter (PICC) parenteral nutrition on immune function and nutritional support after radical gastrectomy for gastric cancer 

  Zhang, Jixun; Si, Xianke; Li, Wei; Yang, Jiahua; Cao, Yijun (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2019-05-26)

  Objective of the present study was to investigate the effects of peripherally inserted central catheter (PICC) parenteral nutrition support on immune function and nutritional support in patients undergoing radical gastrectomy ...
• Effects of dexamethasone combined with ambroxol hydrochloride on T-Cell subsets and hearing in patients with secretory otitis media 

  Xiaorong, Dong; Li, Ma; Xuefeng, Liu; Jian, He (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2019-05-25)

  The aim of the study was to investigate the effect of dexamethasone combined with ambroxol hydrochloride on T cell subsets and hearing in patients with secretory otitis media. Eighty-six cases of patients with secretory ...
• Clinical study of external application of liuhe dan in the treatment of anal edge edema after mixed hemorrhoid operation 

  Wu, Jing; Lu, Wenzhu; Yu, Keqiang; Liu, Hong (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2019-05-24)

  To observe the therapeutic efficacy of external application of Liuhe Dan in the treatment of anal edge edema after mixed hemorrhoid operation. A total of 160 patients who had been treated for lotion anal edge edema from ...
• The curative effect of carvedilol combined with conventional therapy in treatment of chronic heart failure 

  Qu, Wei; Li, Xia; Yu, Zhuxian (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2019-05-23)

  This paper aims to investigate the curative effect of carvedilol combined with conventional therapy in treatment of chronic heart failure. 180 patients who have been treated for chronic heart failure were selected as ...
• Clinical efficacy of mucopolysaccharide polysulfate ointment combined with desonide ointment in treatment of infantile eczema 

  Dang, Yanling; Yang, Lijuan; Jia, Yu; Zhu, Dongning (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2019-05-22)

  To observe and analyze the clinical efficacy of mucopolysaccharide polysulfate (MPS) ointment combined with desonide ointment in treatment of infantile eczema. A total of 180 infants who had been treated for eczema at our ...
• In vitro effect of ulipristal acetate on human sperm parameters and function 

  Sha, Wei; Chang, Xinyi; Han, Yongchun; Miao, Haimin; Yang, Yanli (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2019-05-21)

  To observe and investigate the in vitro effect of ulipristal acetate (UPA) on human sperm parameters and function. The 20 patients with normal semen parameters and average age of (32.5±8.5) years old, who were treated in ...
• Observation of the clinical effect of the combined therapy of zushima tablet and western medicine in the treatment of rheumatoid arthritis and MRI test results 

  Tang, Zhongren; Sun, Quanwei; Ji, Haixia (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2019-05-20)

  To evaluate the clinical efficacy of combined therapy of Zushima tablet and western medicine in treatment of rheumatoid arthritis and analyze the MRI test results. A total of 170 patients who had been treated for rheumatoid ...
• The therapeutic efficacy of high-dose ambroxol and the nursing effects in the treatment of severe pneumonia 

  Wang, Dongmei; Sun, Shu; Hu, Songxue (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2019-05-19)

  To observe and analyze the therapeutic efficacy of high-dose ambroxol in the treatment of severe pneumonia, as well as summarize the nursing methods. A total of 180 patients diagnosed with severe pneumonia and treated at ...
• Topologically significant directed random walk with applied walker network in cancer environment 

  Seah, Choon Sen; Kasim, Shahreen; Saedudin, Rd Rohmat; Md Fudzee, Mohd Farhan; Mohamad, Mohd Saberi; Hassan, Rohayanti; Ismail, Mohd Arfian (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2019-05-18)

  Numerous cancer studies have combined different datasets for the prognosis of patients. This study incorporated four networks for significant directed random walk (sDRW) to predict cancerous genes and risk pathways. The ...
• Effect of carbon dioxide laser (10600nm) on hydroxyproline in mouse skin 

  Min, Ling (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2019-05-17)

  The histological and ultrastructural changes of skin of Wistar rats were compared with 10600nm CO2 dot laser irradiation and external use of A acid preparation. The effects of dot matrix CO2 laser and Nd: YAG laser (quasi ...
• Effect of dexmedetomidine combined with oxycodone patientcontrolled intravenous analgesia on the levels of inflammatory cytokine in patients with rectal cancer 

  Song, Junnian; Wei, Na; Zhang, Jing; Wang, Gang (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2019-05-16)

  This study was designed to discuss the clinical effects of dexmedetomidine combined with oxycodone patientcontrolled intravenous analgesia for patients with laparoscopic radical resection of rectal cancer. A total of 90 ...
• Efficacy of acupoint massage combined with acupoint application on arterial blood gas in patients undergoing laparoscopic cholecystectomy 

  Zhenqing, Ren; Yan, Wang; Weihua, Zhu; Hongmei, Dou; Xiuhong, Cao; Hua, Hong; Azhen, Yuan (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2019-05-15)

  To explore efficacy of acupoint massage combined with acupoint application on arterial blood gas and postoperative complications for patients undergoing laparoscopic cholecystectomy. Patients undergoing laparoscopic ...
• Effect of ticagrelor on brain natriuretic peptide, heart rate and myocardial enzymes in patients with coronary atherosclerotic heart disease after stenting 

  Jia, Dequan; Qin, Bo; Wei, Xiaomei (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2019-05-13)

  The main aim of the current work was to investigate the application of ticagrelor in patients with coronary atherosclerotic heart disease (CAHD) and its effects on brain natriuretic peptide (BNP), heart rate (HR) and ...
• Study on the wound healing, anti-inflammation and anti-bacterial activities of Jinjianling cream: A Chinese herbal compound 

  Zhao, Wu; Zhang, Rongrong; Ma, Cuixia; Qiu, Mingyang; Liu, Yuting; Shao, Shuai; Yan, Mingming; Zhao, Daqing; Gong, Peihan (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2019-05-13)

  The aim of the present study was the healing effect and anti-inflammatory effect of Jinjianling cream on skin lesions and to investigate the antibacterial activity in vitro, which proved that the preparation is safe and ...
• Quercetin inhibition of myocardial fibrosis through regulating MAPK signaling pathway via ROS 

  Min, Zhang; Yangchun, Li; Yuquan, Wang; Changying, Zhang (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2019-05-12)

  Mitogen-activated protein kinase (MAPK) cascades are important players in the cellular signal pathways, and the deregulation of MAPKs is involved in a variety of diseases, especially cardiovascular disorders. This study ...
• Qingnaopian: A Chinese herbal formula in reducing glial fibrillary acidic protein and inflammation in concussion mice 

  Wenying, Lv; Yanteng, Li; Shuai, Liu; Bangxin, Liu; Shengli, Guo; Dong Chao; Jianning, Zhang; Gang, Cheng; Jiaojiao, Xu (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2019-05-11)

  Qingnaopian has been used in traditional Chinese medicine for treating central nervous system (CNS) injury and inflammatory diseases. The aim of this study was to investigate the effects of Qingnaopian in concussion mice. ...
• Effect of vitamin D supplementation on various parameters in non-alcoholic fatty liver disease patients 

  Hussain, Mazhar; Iqbal, Javed; Malik, Saeed Akhtar; Waheed, Akbar; Shabnum, Shazia; Akhtar, Lubna; Saeed, Hira (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2019-05-10)

  There are still no FDA approved drugs for NAFLD so far. Vitamin D may be a good therapeutic option for NAFLD patients due to its insulin sensitizing and anti-inflammatory properties. The purpose is to investigate the ...
• Antibacterial, antidiarrheal, anti-inflammatory and analgesic activities of compound Shikuqin powder 

  Yu, Bo; Yu, Jiankang; Jiang, Lingling; Chen, Xiangxiu; Song, Xu; Zhou, Sixuan; Xu, Jinge; Wu, Jie; Tu, Zhiqiang; Song, Zhiling; Yin, Zhongqiong; Shang, Yishun (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2019-05-09)

  The MIC and MBC values of Shikuqin (SKQ) against 5 bacteria that readily cause diarrhea were measured by the broth micro dilution method. The castor oil-induced diarrhea method was used to evaluate the antidiarrheal ...
• Development, characterization and evaluation of in-vitro anti-inflammatory activity of ginger extract based micro emulsion 

  Akram, Ayesha; Rasul, Akhtar; Waqas, Muhammad Khurram; Irfan, Muhammad; Khalid, Syed Haroon; Aamir, Muhammad Naeem; Murtaza, Ghulam; Rehman, Kashif Ur; Iqbal, Muhammad; Khan, Barkat Ali (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi, 2019-05-08)

  Zingeber officinale is a commonly used plant which has been shown to possess anti-inflammatory activity. The active compounds present in ginger are gingerols, shagaols and paradol. The aim of this study was formulation ...

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