• ALDH2 improved irbesartan treatment efficacy among rats with hypertension 

  Huangfu, Weizhong; Chang, Fuhou; Wang, Minjie; Gao, Ruiying (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2019-09-20)

  Hypertension is a common cardiovascular disease in clinical scenario. The level of leptin changes with the development of hypertension and is regulated by Aldehyde dehydrogenase2 (ALDH2). Our study explored the relationship ...
• Comparison of the efficacy of aerosol inhalation between the ipratropium bromide and terbutaline on the patients with AECOPD 

  Xu, Weiguo; Wu, Junhua; Feng, Yong; Zhu, Jing; Cui, Rong (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2019-09-20)

  To observe the clinical efficacy of aerosol inhalation of ipratropium bromide and terbutaline on the patients with acute exacerbation of chronic obstructive pulmonary disease (COPD). A total of 136 COPD patients with acute ...
• Propofol regulates imbalanced Th17/Treg responses in lipopolysaccharide-induced septic shock rats 

  Xie, Lei; Huang, Li-jun; Wang, Sheng-you; Fang, Xiangdong (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2019-09-20)

  Propofol (PPF) has previously been shown to inhibit the inflammatory response to septic shock. The main purpose of the present study was to investigate the effects of PPF on the levels of regulatory T cells (Treg) and Th17 ...
• Clinical efficacy of nutrition support therapy combined with antibiotics in the patients of community-acquired pneumonia and its influence on serum pct and crp 

  Zhou, Qianqian; Zhang, Liqin; Wang, Xiandong; Wang, Quanhong; Zhang, Dongquan; Yuan, Yuan (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2019-09-20)

  To analyze the clinical efficacy of nutrition support therapy combined with antibiotics in the treatment of patients with ICU severe community-acquired pneumonia and its effect on serum procalcitonin (PCT) and C reactive ...
• Effects of Kuntai capsule on breast pain and vaginal bleeding in postmenopausal women 

  Qi, Xiaoxia; Guo, Yun; Sun, Lingna (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2019-09-20)

  Aim of the present work was to investigate the clinical efficacy of Kuntai capsule in the treatment of postmenopausal women with endometriosis, Breast pain and Vaginal Bleeding. 120 elderly female outpatients over 50 years ...
• Efficacy of different doses of alteplase thrombolysis on acute ischemic stroke in patients 

  Xu, Hongying (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2019-09-20)

  Atyplase is a kind of thrombolytic drug with strong fibrin specificity. It can promote the synthesis of fibrinolytic enzymes by combining fibrin and plasminogen in thrombus, and then dissolve thrombus. Ateplase intravenous ...
• Simultaneous identification of the three active constituents in LungVentilating-Regulating Oral Liquid by RP-HPLC 

  Lu, Lina; Zuo, Yanhua; Wang, Yaoxia; Shi, Yongqing; Kang, Shuhe; Luo, Xingping; Liang, Zuochong; Chen, Lihua (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2019-09-20)

  The study aimed to develop a HPLC method for ephedrine, hesperidin, and baicalin in Lung-VentilatingRegulating Oral Liquid. The three active constituents were identified in an Agilent TC-C18 (2) chromatographic column ...
• Observation of nursing effect for patients with primary liver cancer before and after transcatheter arterial embolization 

  Luan, Lan; Wang, Lin (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2019-09-20)

  To observe and analyze the nursing effect of primary liver cancer before and after transcatheter arterial embolization. The 200 patients with advanced primary liver cancer who had been treated in the Second People’s Hospital ...
• The value of erythromycin pleurodesis in treatment of spontaneous pneumothorax 

  Sun, Zhenjie; Gao, Xia; Meng, Qinghua; Ma, Naihua; Han, Kai; Du, Gang (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2019-09-20)

  The research was carried out to observe the effect of erythromycin pleural fixation in treatment of spontaneous pneumothorax. The 160 patients who had been treated for spontaneous pneumothorax were selected as research ...
• Pharmacology of atorvastatin on myocardial ischemia-reperfusion in rats and drug effect analysis 

  Cao, Bingfeng; Bi, Guofeng; Wang, Yufeng (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2019-09-20)

  Statins are the most important drugs in the treatment of atherosclerosis. In this paper, the authors analyze the protective effect of atorvastatin on myocardial ischemia-reperfusion in rats and its drug effect. The results ...
• Effects of purulent meningitis on the changes of matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase inhibitor-1 (TIMP-1) in cerebrospinal fluid of neonates 

  Cui, Weijing; Luo, Xuan; Zhang, Yunjuan (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2019-09-20)

  This study was aimed to investigate the changes of matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase inhibitor-1 (TIMP-1) in cerebrospinal fluid (CSF) of neonates with purulent meningitis. 195 cases (n=195) ...
• Comparative effects of 2.5mg levamlodipine and 5mg amlodipine on vascular endothelial function and atherosclerosis 

  Lu, Yinhui; Yin, Juan; Wu, Xiaohe; Fan, Yuqin; Liu, Fenfen (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2019-09-20)

  This study was designed to compare the efficacy of two different racemic antihypertensive drugs on elderly patients with hypertension and their effects on vascular endothelial function and atherosclerosis. A total of 84 ...
• Efficacy and safety of NAD+ ADP-ribosyltransferase 1 agonist versus Donepezil in elderly Chinese patients with Alzheimer disease: A novel target for effective therapy 

  Wang, Jianhong; Yang, Shu; Hu, Zicheng; Yang, Haimei; Wei, Dong; Wang, Duozi; Guo, Fuqiang (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2019-09-20)

  This pilot study designed to evaluate the efficacy and safety of NAD+ ADP-ribosyl transferase 1 (NART) agonist in comparison with Donepezil (DNP) in elderly Chinese patients with Alzheimer disease (AD). In the present ...
• Analysis of comparative anesthetic effects of sevoflurane and propofol on lung and cognitive functions 

  Zhiguo, Yuan; Nanxiang, Zhou; Jinyu, Man (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2019-09-20)

  This study was designed to compare the effects of TIVA (total intravenous anesthesia) by propofol and sevoflurane inhalation on perioperative inflammatory response, pulmonary function and postoperative cognitive function ...
• Clinical effect and safety of nifedipine controlled-release tablets combined with valsartan in the treatment of primary hypertension 

  Liu, Wenhui; Liu, Yanyang; Fu, Jing (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2019-09-20)

  To observe and analyze the clinical effect of nifedipine controlled-release tablets combined with valsartan in the treatment of essential hypertension, and to analyze the adverse reactions of patients. A total of 180 ...
• Study on the treatment of advanced lung adenocarcinoma in the elderly with pemetrexed combined with platinum drugs 

  Ba, Xiumin; Han, Jinhua; Zhao, Guohong; Bian, Li (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2019-09-20)

  To study the treatment of advanced lung adenocarcinoma in the elderly with pemetrexed combined with platinum drugs. 200 elderly patients who had been treated for advanced lung adenocarcinoma in our hospital were enrolled ...
• Clinical observation of minocycline hydrochloride ointment in the treatment of early peri-implantitis 

  Tian, Bao (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2019-09-20)

  To observe and analyze the therapeutic efficacy of minocycline hydrochloride ointment in the treatment of early peri-implantitis. A total of 180 patients with early peri-implantitis and treated at our hospital were enrolled. ...
• Evaluation of prokinetic and laxative effects of Hippophae rhamnoides in rodents 

  Hanif, Muhammad; Mehmood, Malik Hassan; Ishrat, Ghazala; Abdullah, Ahmed; Sohail, Samar; Ahmed, Mansoor; Gilani, Anwarul-Hassan (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2019-09-20)

  Hippophae rhamnoides (Family; Elaeagnaceae) fruit extract was investigated for prokinetic and gut excitatory effects to rationalize its therapeutic utility in gastrointestinal complaints like delayed gastric emptying and ...
• Antifungal and anti-aflatoxin efficacy of biogenic silver nanoparticles produced by Aspergillus species: Molecular study 

  Ibrahim Al-Zaban, Mayasar; Shazli, Nahla; Azim, Abdel; Ramadan Mohamed, Abeer; Abd El-Aziz, Mohamed (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2019-09-20)

  Date palm (Phoenix dactylifera L.) is considered the main crop in deserts and arid areas such as Saudi Arabia. Fifteen species belonging to 7 fungal genera were isolated from date palm rhizosphere soil at Riyadh, Saudi ...
• Impact of formulation variables on weight uniformity of scored tablets using factorial design 

  Zaid, Abdel Naser; Hawari, Raghda; Malkieh, Numan; Natshih, Yasmin; Yousef, Abeer; Jaradat, Nidal; Hammad, Aysha; Basharat, Rebhi (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2019-09-20)

  Maintaining safety and efficacy is an important task when splitting a tablet. This Pharmacy practice affords the patient with unavailable required dose, easy swallowing, and cost-saving measure. To access the role of ...

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