dc.contributor.author |
Rattana, Surapong |
|
dc.contributor.author |
Katisart, Teeraporn |
|
dc.contributor.author |
Butiman, Chirapha |
|
dc.contributor.author |
Sungthong, Bunleu |
|
dc.date.accessioned |
2022-12-02T03:45:47Z |
|
dc.date.available |
2022-12-02T03:45:47Z |
|
dc.date.issued |
2019-11-01 |
|
dc.identifier.citation |
Rattana, S., Katisart, T., Butiman, C., & Sungthong, B. (2019). Total flavonoids, total phenolics, 1-deoxynojirimycin content and alpha-glucosidase inhibitory activity of Thai silkworm races (Bombyx mori Linn.). Pakistan Journal of Pharmaceutical Sciences, 32(6). |
en_US |
dc.identifier.issn |
1011-601X |
|
dc.identifier.uri |
http://142.54.178.187:9060/xmlui/handle/123456789/14477 |
|
dc.description.abstract |
The silkworm powder (Bombyx mori Linn.) from Japanese and Korean races has well known used as a blood
glucose lowering substance. However, the study of bioactive compounds and hypoglycemic effect on Thai silkworm races is still limited. This study was aimed to investigate the flavonoid, phenolic and 1-deoxynojirimycin (DNJ) contents, and α-glucosidase inhibitory activity of three Thai silkworm races (Nanglai, Nangnoi and Samrong) of the 5th instar, 2nd 4 th day silkworm powders. The total flavonoid, phenolic contents and α-glucosidase inhibitory activity were performed using spectrophotometric methods. The DNJ content was determined using derivatization and further analyzed by HPLC. Nangnoi showed the highest flavonoid content with 12.32±0.41mg quercetin equivalent/g silkworm powder. Nanglai showed the highest phenolic content with 78.74±1.43mg gallic acid equivalent/g silkworm powder. Regarding DNJ content, Nangnoi expressed the highest at 3.11±0.01mg/g silkworm powder. According to the age of silkworm, powders of the instar 5th, day 3rd were provided the highest α-glucosidase inhibitory activity (p<0.05). This study clearly indicated that the 5th instar, 3rd day of Thai silkworms exhibited the highest flavonoid, phenolic, DNJ contents and α-glucosidase
inhibitory activity. Further study on blood glucose lowering activity should be performed. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi |
en_US |
dc.subject |
Flavonoids |
en_US |
dc.subject |
phenolic compounds |
en_US |
dc.subject |
1-deoxynojimycin (DNJ) content |
en_US |
dc.subject |
α-glucosidase inhibitor |
en_US |
dc.subject |
Thai silkworm (Bombyx mori Linn.) |
en_US |
dc.title |
Total flavonoids, total phenolics, 1-deoxynojirimycin content and alpha-glucosidase inhibitory activity of Thai silkworm races (Bombyx mori Linn.) |
en_US |
dc.type |
Article |
en_US |