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Submerged cultivation of medicinal mushroom in hydrolysate of lignocellulosic material

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dc.contributor.author Kausar, Shamaila
dc.contributor.author Zia, Sadia
dc.contributor.author Nadeem, Zainab
dc.contributor.author Murtaza, Mian Anjum
dc.contributor.author Hafiz, Iram
dc.contributor.author Shaheen, Bashir Ahmad
dc.contributor.author Hazrat, Ali
dc.contributor.author Jan, Tour
dc.contributor.author Mukhtiar, Muhammad
dc.contributor.author Sher, Falk
dc.contributor.author Tahir, Imtiaz Mahmood
dc.contributor.author Akram, Muhammad
dc.contributor.author Khan, Fahad Said
dc.date.accessioned 2022-12-05T04:18:24Z
dc.date.available 2022-12-05T04:18:24Z
dc.date.issued 2019-11-10
dc.identifier.citation Kausar, S., Zia, S., Nadeem, Z., Murtaza, M. A., Hafiz, I., Shaheen, B. A., ... & Khan, F. S. (2019). Submerged cultivation of medicinal mushroom in hydrolysate of ligno-cellulosic material. Pak J Pharm Sci, 33, 2835-2841. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/14596
dc.description.abstract Ganoderma lucidum belongs to the family Ganodermataceae and found in Japan, China and some other parts of Asia. Traditionally it is used in herbal medicine as anti-diabetic, cancer prevention agent, antitumor, an immunomodulatory, antimicrobial and antiviral agent. Due to difficulty in field cultivation, submerged fermentation was employed as a promising method for efficient and large-scale production of mycelia biomass and bioactive metabolites. Cellulose was used in the form of a lignocellulosic substrate. The Ganoderma lucidum which is medicinal and edible mushrooms were successfully grown in the form of mycelial biomass in static submerged culture in Petri plates and flasks. The present study is based on the utilization of hydrolyzates of lignocellulosic materials such as Peanut cort, Sugarcane bagasse, and Wheat Straw was used after hydrolysis. A Static Fermentation Technique was employed to investigate the mycelial growth, instead of Fruiting Body. Ganoderma lucidum was kept up on PDA (potato dextrose agar) medium in Petri dishes at 4oC and brooded at 25 ◦C for 5 days for the development of G. lucidum and generation of Ganoderic Acid. Morphology of G. lucidum on various Hydrolysates was white and delicate like cotton unpredictable shape, Cloud-like appearance spread in general plate and multiple little sporadic white cotton-like shape with string-like projections. We got a Ganoderic Acid from the Hydrolysates of Peanut cort concentrate, Sugarcane bagasse concentrate and Wheat straw concentrate at a concentration of 0.006g/L, 0.011g/L and 0.017g/L respectively. en_US
dc.language.iso en en_US
dc.publisher Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi en_US
dc.subject Ganoderma lucidum en_US
dc.subject hydrolysate of ligno-cellulosic material en_US
dc.subject static fermentation technique en_US
dc.subject mycelia growth en_US
dc.title Submerged cultivation of medicinal mushroom in hydrolysate of lignocellulosic material en_US
dc.type Article en_US


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