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Depression and dementia from hyponatremia in brain cancer patients exposed to frozen food chemicals

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dc.contributor.author Khalid, Sana
dc.contributor.author Shahid, Saman
dc.contributor.author Rasheed, Sajid
dc.contributor.author Iftikhar, Sadaf
dc.contributor.author Hussain, Syed Shahzad
dc.contributor.author Ghayyur, Aysha
dc.contributor.author Chaudhry, Muhammad Nawaz
dc.date.accessioned 2022-12-05T04:33:02Z
dc.date.available 2022-12-05T04:33:02Z
dc.date.issued 2019-11-13
dc.identifier.citation Khalid, S., Shahid, S., Rasheed, S., Iftikhar, S., Hussain, S. S., Ghayyur, A., & Chaudhry, M. N. (2019). Depression and dementia from hyponatremia in brain cancer patients exposed to frozen food chemicals. Pakistan Journal of Pharmaceutical Sciences, 32. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/14600
dc.description.abstract Frozen food chemicals contain neurotoxins which disturb electrolyte levels. Altered electrolyte levels can induce mental illnesses. This study was focused on finding the prevalence of depression, dementia, intake of antidepressants and electrolytic alterations in brain cancer (BC) patients and in control group (CG) who were taking frozen and canned food. The levels of electrolytes were compared in both groups through Mann-Whitney U test. The Odds Ratio (OR) and Relative Risks (RR) were calculated of having a specific occurrence or condition of brain cancer patients vs. controls. Majority (41.42%) patients were from the age group 33-57 years. There were 52% male and 47% female patients. There was more occurrence of dementia (41%) and depression (6%) in patients as compared to CG. 94% patients were found with dementia. 32% patients were having low levels of sodium and 43% were having low levels of potassium. High levels of potassium (26%) were found in CG. 76% patients and 73% controls were taking canned food in moderation. 69% patients and 50% controls were taking frozen food in moderation. The potassium levels (p value: 0.00001) and sodium levels (p value: 0.01468) were found at significant difference in brain cancer patients and control group. Statistically significantly higher odds of outcome (OR>1) and increased relative risks (RR) were reported in dementia, depression and intake of anti-depressants for BC vs. CG. This epidemiological study reports hyponatremia as a significantly different parameter between brain cancer patients and controls. Food’s chemicals induce hyponatremia, which can disturb mental states to develop different neurological conditions. en_US
dc.language.iso en en_US
dc.publisher Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi en_US
dc.subject Brain cancer en_US
dc.subject anti-depressants en_US
dc.subject depression en_US
dc.subject frozen food en_US
dc.subject sodium chemical en_US
dc.subject hyponatremia en_US
dc.subject hyperkalemia en_US
dc.title Depression and dementia from hyponatremia in brain cancer patients exposed to frozen food chemicals en_US
dc.type Article en_US


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