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Study on the treatment of advanced lung adenocarcinoma in the elderly with pemetrexed combined with platinum drugs

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dc.contributor.author Ba, Xiumin
dc.contributor.author Han, Jinhua
dc.contributor.author Zhao, Guohong
dc.contributor.author Bian, Li
dc.date.accessioned 2022-12-06T04:35:45Z
dc.date.available 2022-12-06T04:35:45Z
dc.date.issued 2019-09-20
dc.identifier.citation Ba, X., Han, J., Zhao, G., & Bian, L. (2019). Study on the treatment of advanced lung adenocarcinoma in the elderly with pemetrexed combined with platinum drugs. Pakistan Journal of Pharmaceutical Sciences, 32. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/14686
dc.description.abstract To study the treatment of advanced lung adenocarcinoma in the elderly with pemetrexed combined with platinum drugs. 200 elderly patients who had been treated for advanced lung adenocarcinoma in our hospital were enrolled as research objects. They were randomly divided into control group and research group, each containing 100 patients. The control group was given Pemetrexed therapy and routine nursing mode, while the research group was given pemetrexed combined with platinum drugs and evidence-based nursing mode. The therapeutic effect and nursing effect of the two groups were compared. The overall treatment effective rate of the research was 85.00% and that of the control group was 60.00%, indicating the research group had significant advantage over the control group, p<0.05. The incidence of adverse reactions including nausea, vomiting, constipation, diarrhea, bone marrow suppression, fatigue and fatigue, and hair loss was significantly lower in the research group (22.00%) than that in the control group (45.00%), p<0.05. The quality of life of the research group was higher than that of the control group, p<0.05. For the elderly patients with advanced lung adenocarcinoma, the implementation of pemetrexed combined with platinum drug can help patients get better treatment results. en_US
dc.language.iso en en_US
dc.publisher Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi. en_US
dc.subject Pemetrexed en_US
dc.subject platinum drugs en_US
dc.subject combination therapy en_US
dc.subject elderly patients en_US
dc.subject advanced lung adenocarcinoma en_US
dc.title Study on the treatment of advanced lung adenocarcinoma in the elderly with pemetrexed combined with platinum drugs en_US
dc.type Article en_US


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