• Isolation and identification of endophytic fungi from Dendrobium huoshanense with their antibacterial and anti-inflammatory activities 

  Yue, Jing-Yi; Yu, Yang (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2022-07-20)

  To examine the symbiotic relationship between Dendrobium huoshanense and its endophytic fungi, a total of 168 endophytic fungi were isolated and classified into 18 genera and 36 species via using pure culture and techniques ...
• Optimization and fabrication of the nanosponge carriers of on dansetron using one-factor design 

  Salawi, Ahmad; Alam, Mehwish; Zaman, Muhammad (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2022-07-20)

  The current studies were aimed to formulate ethyl cellulose (EC), beta-cyclodextrin βCD facilitated EC based Ondansetron nanosponges (NS) using Response Surface Methodology (RSM) by employing One Factor Design. The NS ...
• Screening and estimation of antibacterial activity of bacteriocins produced by Enterococcus faecium LR isolated from raw horse milk samples 

  Kadi, Roqayah Hassan; Baghdadi, Afra Mohammed (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2022-07-20)

  Lactic acid bacteria are microorganisms that can be present in meat, milk and fermented products, as well as fermented drinks and vegetables, and they inhibit the growth of pathogenic and decaying microorganisms. Our aim ...
• Synthesis, biological screening and docking studies of some indole derivatives as potential antioxidant 

  Ansari, Sumaira; Mushtaq, Nousheen; Ahmed, Ahsaan; Asghar, Saira; Munawar, Rabya; Saify, Zafar Saied (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2022-07-20)

  The present study envisioned some antioxidant candidates having 1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole (TRY), 3-(2-bromoethyl)indole (BEI) and 7-azindole (AI) nucleus. Derivatives of these indole molecules were synthesized ...
• Ultra-sound assisted extraction, anti-oxidant, cytotoxic and antimicrobial studies of Moringa oleifera flowers 

  Talath, Sirajunisa; Wali, Adil Farooq; K, Hemalatha; Menezes, Godfred Antony (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2022-07-20)

  The study was undertaken to determine antioxidant, anticancer and antimicrobial activities of Moringa oleifera flowers. We used three different solvents, hexane (MOF-H), ethyl acetate (MOF-EA) and methanol (MOF-M), to ...
• Determination of ionization constant and drug-likeness prediction of synthetic isoniazid derivatives 

  Zafar, Shaista; Akhtar, Shamim; Mushtaq, Nousheen; Imran Ali, Syed; Ahmed, Ahsaan; Naeem, Sabahat (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2022-07-20)

  Determination of ionization constant, commonly termed pKa is of prime interest in a wide range of pharmaceutical Research fields. The pKa of a compound is critical as it influences on its physicochemical parameters in ...
• Variation in quality of the different prepared formulation granules of rhubarb was evaluated by quantitative analysis of multicomponents with single marker 

  Fan, Xiao-liang; Zhang, Chun; Shi, Yan-bo; Xue, Lei-bing; Wei, Jing-jing (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2022-07-20)

  Rhei Radix et Rhizoma formula granule (RRFG) , Winy Rhei Radix et Rhizoma formula granule(WRFG) and Rhubarb charcoal formula granules (RCFG) are the three most popular and effective formula granules of rhubarb in China and ...
• Comparative effects of tocopherol and ubiquinol on arsenic induced nephrotoxicity in sprague dawley rats 

  Mir, Urfa Zaryab; Rashid, Amir; Waheed, Palvasha; Yousaf, Javad; Mir, Amaidah (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2022-07-20)

  Millions of the people worldwide are drinking arsenic polluted water. The need of time is to find out the mitigation strategies to cope with this issue. To evaluate the effects of tocopherol and ubiquinol individually and ...
• Effect on ethanolic extract of Sechium edule fruitson imquimodinduced psoriasis like dermatitis in wistar rats 

  SM, Firdous; Sarkar, Dibakar; Samuel Kelechi, Mobisson; AAl-Haidari, Rwaida; Al Busaidi, Harith N; Samman, Waad; Alhaddad, Aisha; AH Mostafa, Mahmoud (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2022-07-20)

  The purpose of this study was to find out if the ethanolic fruit extract of Sechium edule fruits could prevent Imquimod (IMQ)-induced psoriasis-like dermatitis in male Wistar rats. The rats were divided into four groups ...
• Effect of garlic essential oil in 97 patients hospitalized with covid-19: A multi-center experience 

  Wang, Yaling; Wu, Yanming; Fu, Ping; Zhou, Hongfen; Guo, Xiaochun; Zhu, Chuanwu; Tu, Yifeng; Wang, Jianfei; Li, Huiling; Chen, Zutao (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2022-07-20)

  To observe the synergistic effect of garlic essential oil in patients with novel coronavirus disease (COVID-19), in addition to the routine treatment, we used garlic essential oil in COVID-19 patients with mild to moderate ...
• Glycemic control and antioxidant potential of distinct fractions of camelus dromedaries fresh milk in streptozocin induced diabetic rats 

  Ashraf, Rizwan; Sarwar, Muhammad; Kamil, Noor; Qureshi, Absar; Waheed, Shahid (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2022-07-20)

  To analyze the antiglycemic effects and to evaluate the anti-oxidant levels in pre and post-camel milk fractions treated albino diabetic rats, sixty male Swiss albino rats weighing 30-40gm aged 2 to 3 months were randomly ...
• Spectrum-effect relationship between hplc fingerprint and antiinflammatory activity of n-butanol parts of Tetrastigma planicaule (Hook) Gagnep 

  Qiu, Qin; Shi, Junhao; Huang, Chunying; Liu, Yuwen; Zhen, Dandan; Liu, Xiaofang; Gu, Bao-jun; Jiang, Lujuan; Liu, Yuan-yuan (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2022-07-20)

  The present study aimed to evaluate the spectrum-effect relationships between high-performance liquid chromatography fingerprints and anti-inflammatory effects of Tetrastigma planicaule(Hook.)Gagnep. Chemical fingerprints ...
• Mechanisms of natural products as potential antiepileptic drugs 

  Ahmad, Nurulumi; Hui-Yin, Yow (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2022-07-20)

  The universal epileptogenic cascade remains unknown, and most modern treatments focus on the reduction of symptoms and the prevention of seizure recurrence. Experimental studies have demonstrated that herbal medicines may ...
• Determination of components in Radix paeoniae rubra based on QAMS 

  Ling-feng, Yue; Xiao-wei, Huang; Jian-feng, Gao; lian, Zhanghong; Dong-mei, Wang; Ji-kai, Sun; Zhi-guo, Zhang; Jing-han, Wang; Jun, Liu; Yu-mei, Wang; Qi, Liu; Hong-jun, Liu; Yue-yu, Lu; Yan, Li (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2022-07-20)

  The current study aimed to establish simple and quick quality evaluation method of Chishao based on QAMS. Oxypaeoniflorin is used as a marker in the Chishao root. Based on it, the content of other components could be ...
• Death receptor-dependent apoptosis and cell cycle delay induced by bioymifi in human cervical cancer cells 

  Altun, Ahmet; Şahin Inan, Zeynep Deniz; Yulak, Fatih (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2022-07-20)

  In chemotherapy applied against cervical cancer, non-specific cytotoxicity and drug resistance that develops over time are trying to be overcome. Therefore, the development of effective and innovative chemotherapeutic drugs ...
• Protective role of Avena fatua against drug-induced liver toxicity 

  Ishtiaq, Sania; Qureshi, Shamim Akhtar; Aziz, Syed Abdul (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2022-07-20)

  The study was conducted to examine the protective potential of ethanol seed extract (ESEt) of Avena fatua (wild oats) against antituberculosis drug (ATD)-induced hepatotoxicity in rats. Four groups of rats (n=6) were used. ...
• Ethanol extract of Nepeta angustifoia C. Y. Wu ameliorates hyperuricemia in fructose-induced mice 

  Wang, Minzhu; Zhuoma, Dongzhi; Yuan, Ruiying; Wang, Yuefei; Pu, Zhen; Zeren, Lamu; Wang, Jule; Tan, Meng; Huang, Shan (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2022-07-20)

  As a popular medicinal plant traditionally used in Tibet of China, Nepeta angustifolia C. Y. Wu is mainly administered to treat apoplexia, cerebral haemorrhage, fainting and epilepsy and other symptoms, while its effect ...
• Formulation and characterization of orodispersible film containing diltiazem hydrochloride with taste masked effects 

  Latif, Sumera; Kokab, Ambreen; Afzal, Hafsa; Shoaib, Qurat-ul ain; Hameed, Misbah; Manzoor, Mobina; Batool, Nighat; Amir Ijaz, Qazi (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2022-07-20)

  Orodispersible film (ODF) is a better alternate to oral disintegrating tablets owing to its ease in application and subsequent patient compliance. This study investigates an improvement in physico-mechanical properties and ...
• Clinical efficacy of gouty tea on chronic gouty arthritis and its effects on serum vascular endothelial function and inflammatory cytokines 

  Hua, Liu; Zhi-gang, Cai; Hai-lin, Bao; Ai-chun, Wei; Xiao-jian, Wang; Xiao-lin, Fan; Wan-hong, LI (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2022-07-20)

  To observe the efficacy of Gouty Tea on chronic gouty arthritis and its effect on vascular endothelial function and inflammatory factor levels. Totally 120 patients with chronic gouty arthritis were divided into control ...
• A clinical audit to evaluate antibiotic prescribing practice in pediatric patients admitted for enteric fever. Rationalizing antibiotic stewardship program 

  Hussain, Abdullah; Asghar, Usman; Gill, Iram Asghar; Shahid, Maryam; Shahid, Ayesha; Nabeel Hassan, Muhammad; Ali, Iftikhar; Naheed, Fatima; Numan Zahid, Muhammad (Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi., 2022-07-20)

  To evaluate the antibiotic prescribing practice in pediatric patients for enteric fever, and to assess the need of developing and implementing the Antibiotic Stewardship Program (ASP) for the hospital. A prospective audit ...

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