dc.contributor.author |
Zhou, Xiaomeng |
|
dc.contributor.author |
Fang, Liang |
|
dc.contributor.author |
Tong, Xuefei |
|
dc.contributor.author |
Xu, Ying |
|
dc.contributor.author |
Wu, Xue |
|
dc.date.accessioned |
2022-12-07T04:40:54Z |
|
dc.date.available |
2022-12-07T04:40:54Z |
|
dc.date.issued |
2022-05-04 |
|
dc.identifier.citation |
Zhou, X., Fang, L., Tong, X., Xu, Y., & Wu, X. (2022). Clinical efficacy of clonazepam in the treatment of status epilepticus. Pakistan Journal of Pharmaceutical Sciences, 35(3 (Special)), 891-895. |
en_US |
dc.identifier.issn |
1011-601X |
|
dc.identifier.uri |
http://142.54.178.187:9060/xmlui/handle/123456789/14804 |
|
dc.description.abstract |
To explore the clinical efficacy of clonazepam in the treatment of status epilepticus. Totally 60 patients with
status epilepticus were identified as research subjects and assigned (1:1) via the randomized double-blind method to receive either diazepam (Valium) comparison group) or clonazepam (observation group). After treatment and follow-up visits, the treatment efficacy, incidence of adverse reactions, quality of life, and recurrence were evaluated and compared between the two groups. The total effective rate of the observation group was 93.33%, which was higher than that of 66.67% in the comparison group (P<0.05). A longer mean duration of drug effect was observed in the observation group than in the comparison group (P<0.05). The observation group outperformed the comparison group in terms of quality of life (P<0.05). The observation group had a lower incidence of adverse reactions than the comparison group (P<0.05). The overall recurrence rate in the comparison group was 23.33%, which was significantly higher than that of 6.67% in the observation group (P<0.05). Clonazepam yields a promising efficacy in the treatment of patients with status epilepticus. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi |
en_US |
dc.subject |
Status epilepticus |
en_US |
dc.subject |
clonazepam |
en_US |
dc.subject |
curative effect |
en_US |
dc.subject |
adverse reactions |
en_US |
dc.subject |
reoccurrence |
en_US |
dc.title |
Clinical efficacy of clonazepam in the treatment of status epilepticus |
en_US |
dc.type |
Article |
en_US |