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Clinical efficacy of clonazepam in the treatment of status epilepticus

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dc.contributor.author Zhou, Xiaomeng
dc.contributor.author Fang, Liang
dc.contributor.author Tong, Xuefei
dc.contributor.author Xu, Ying
dc.contributor.author Wu, Xue
dc.date.accessioned 2022-12-07T04:40:54Z
dc.date.available 2022-12-07T04:40:54Z
dc.date.issued 2022-05-04
dc.identifier.citation Zhou, X., Fang, L., Tong, X., Xu, Y., & Wu, X. (2022). Clinical efficacy of clonazepam in the treatment of status epilepticus. Pakistan Journal of Pharmaceutical Sciences, 35(3 (Special)), 891-895. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/14804
dc.description.abstract To explore the clinical efficacy of clonazepam in the treatment of status epilepticus. Totally 60 patients with status epilepticus were identified as research subjects and assigned (1:1) via the randomized double-blind method to receive either diazepam (Valium) comparison group) or clonazepam (observation group). After treatment and follow-up visits, the treatment efficacy, incidence of adverse reactions, quality of life, and recurrence were evaluated and compared between the two groups. The total effective rate of the observation group was 93.33%, which was higher than that of 66.67% in the comparison group (P<0.05). A longer mean duration of drug effect was observed in the observation group than in the comparison group (P<0.05). The observation group outperformed the comparison group in terms of quality of life (P<0.05). The observation group had a lower incidence of adverse reactions than the comparison group (P<0.05). The overall recurrence rate in the comparison group was 23.33%, which was significantly higher than that of 6.67% in the observation group (P<0.05). Clonazepam yields a promising efficacy in the treatment of patients with status epilepticus. en_US
dc.language.iso en en_US
dc.publisher Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi en_US
dc.subject Status epilepticus en_US
dc.subject clonazepam en_US
dc.subject curative effect en_US
dc.subject adverse reactions en_US
dc.subject reoccurrence en_US
dc.title Clinical efficacy of clonazepam in the treatment of status epilepticus en_US
dc.type Article en_US


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