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Effects of atorvastatin and Zishen Qingqi granules on immune function and liver function of patients with systemic lupus erythematosus with mild and moderate activity

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dc.contributor.author Sun, Yuzi
dc.contributor.author Yuan, Lili
dc.contributor.author Liu, Xinrui
dc.contributor.author Yu, Wenjuan
dc.contributor.author Li, Jie
dc.date.accessioned 2022-12-07T05:31:37Z
dc.date.available 2022-12-07T05:31:37Z
dc.date.issued 2022-05-11
dc.identifier.citation Sun, Y., Yuan, L., Liu, X., Yu, W., & Li, J. (2021). Effects of atorvastatin and Zishen Qingqi granules on immune function and liver function of patients with systemic lupus erythematosus with mild and moderate activity. Pakistan Journal of Pharmaceutical Sciences, 34. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/14815
dc.description.abstract To explore the effect of atorvastatin combined with Zishen Qingqi Granules on the immune function and liver function of patients with mild to moderate activity systemic lupus erythematosus. The data of 120 patients with mild to moderate activity systemic lupus erythematosus admitted to our hospital from February 2019 to February 2020 were retrospectively analyzed and they were divided into experimental group (n=60) and the control group (n=60) according to the order of admission; the control group was treated with atorvastatin, and the experimental group was treated with Zishen Qingqi Granules plus. The immune function, liver function, TCM syndrome score and systemic lupus erythematosus disease activity index (SLEDAI) were compared between the two groups. The experimental group after treatment was superior to the control group with respect to immune function indexes, liver function indexes, SLEDAI and TCM syndromes (all P<0.001). Atorvastatin combined with Zishen Qingqi Granules can improve the liver function of patients with mild to moderate activity systemic lupus erythematosus, enhance their immunity, and relieve their clinical symptoms. en_US
dc.language.iso en en_US
dc.publisher Karachi: Faculty of Pharmacy & Pharmaceutical Sciences, Karachi en_US
dc.subject Atorvastatin en_US
dc.subject Zishen Qingqi granules en_US
dc.subject systemic lupus erythematosus en_US
dc.title Effects of atorvastatin and Zishen Qingqi granules on immune function and liver function of patients with systemic lupus erythematosus with mild and moderate activity en_US
dc.type Article en_US


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