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Pharmacological analysis of hydroethanolic extract of Senna alata (L.) for in vitro free radical scavenging and cytotoxic activities against HepG2 cancer cell line

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dc.contributor.author Sugumar, Mohanasundaram
dc.contributor.author Doss, Victor Arokia
dc.contributor.author Maddisetty, Prasad
dc.contributor.author Rangaraju, Magesh
dc.contributor.author Kandhasamy, Sivakumar
dc.contributor.author Munuswamy, Subathra
dc.date.accessioned 2022-12-12T11:11:17Z
dc.date.available 2022-12-12T11:11:17Z
dc.date.issued 2019-05-06
dc.identifier.citation Sugumar, M., Doss, V. A., Maddisetty, P., Rangaraju, M., Kandhasamy, S., & Munuswamy, S. (2019). Pharmacological analysis of hydroethanolic extract of Senna alata (L.) for in vitro free radical scavenging and cytotoxic activities against HepG2 cancer cell line. Pakistan Journal of Pharmaceutical Sciences, 32(3), 933-936. en_US
dc.identifier.issn 2070-3368
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/14926
dc.description.abstract The main objective of this study was to evaluate the hydroethanolic extract of Senna alata for the possible free radical scavenging and cytotoxic properties. Using such hydroethanolic extract, various in vitro antioxidant assays at different concentrations were performed and analyzed. In all the assays, plant extract has good inhibitory effect. Ethanolic extract of Senna alata was further subjected into cytotoxicity against HepG2 cell line. Accordingly, it was also found that the plant extract has appreciable potency against cancer cell lines. en_US
dc.language.iso en en_US
dc.publisher Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi en_US
dc.subject Senna alata en_US
dc.subject antioxidant en_US
dc.subject lipid peroxidation en_US
dc.subject antioxidant en_US
dc.subject anticancer en_US
dc.title Pharmacological analysis of hydroethanolic extract of Senna alata (L.) for in vitro free radical scavenging and cytotoxic activities against HepG2 cancer cell line en_US
dc.type Article en_US


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