PASTIC Dspace Repository

Immune boosting role of vitamin E against pulmonary tuberculosis

Show simple item record

dc.contributor.author Hussain, Muhammad Imran
dc.contributor.author Ahmed, Waqas
dc.contributor.author Nasir, Muhammad
dc.contributor.author Mushtaq, Muhammad Hassan
dc.contributor.author Sheikh, Ali Ahmad
dc.contributor.author Shaheen, Arfat Yousaf
dc.contributor.author Mahmood, Ashraf
dc.date.accessioned 2022-12-13T09:39:53Z
dc.date.available 2022-12-13T09:39:53Z
dc.date.issued 2019-01-05
dc.identifier.citation Hussain, M. I., Ahmed, W., Nasir, M., Mushtaq, M. H., Sheikh, A. A., Shaheen, A. Y., & Mahmood, A. (2019). Immune boosting role of vitamin E against pulmonary tuberculosis. Pakistan Journal of Pharmaceutical Sciences, 36(1SI), 269-277. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/14989
dc.description.abstract Tuberculosis is one of the leading causes of mortality in Pakistan which is linked with malnutrition and weak immunity. Such people are more prone to chronic infections including TB. The current study aimed to assess the effect of supplementation of Vitamin E on the immune status of human subjects against pulmonary tuberculosis. A total of 80 patients with pulmonary TB were divided into treatment group (vitamin E) and control group (Anti-tuberculosis regime). Presence of acid fast bacilli in sputum sample, Erythrocyte sedimentation rate, total leucocytes counts, body mass index and mid arm muscle circumference (MAMC) were recorded as per standard protocol. Levels of vitamin E, IgG, IgM and T-Cell count were determined before and after treatment. The results showed that 16% males and 33% females were underweight who consumed 1145 kcal energy instead of 2270 kcal per day and 19.5 gram protein instead of 78.6 grams. A non significant effect of vitamin E on ESR and TLC values was observed but significant increase in level of immunoglobulins (IgG, IgM) and T-cell types (CD4+ and CD8+ ) was observed in patients as compared to control group. Results indicate that vitamin E plays important role in enhancing immunity of patients against TB. en_US
dc.language.iso en en_US
dc.publisher Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi en_US
dc.subject Tuberculosis en_US
dc.subject malnutrition en_US
dc.subject vitamin E en_US
dc.subject BMI en_US
dc.subject MAMC. en_US
dc.title Immune boosting role of vitamin E against pulmonary tuberculosis en_US
dc.type Article en_US


Files in this item

This item appears in the following Collection(s)

Show simple item record

Search DSpace


Advanced Search

Browse

My Account