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Biologically active compounds from the red sea sponge Suberea sp.

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dc.contributor.author Shaala, Lamiaa A
dc.contributor.author Almohammadi, Ameen
dc.date.accessioned 2022-12-15T05:17:21Z
dc.date.available 2022-12-15T05:17:21Z
dc.date.issued 2017-11-10
dc.identifier.citation Shaala, Lamiaa A., and Ameen Almohammadi. "Biologically active compounds from the red sea sponge Suberea sp." Pak. J. Pharm. Sci 30, no. 6 (2017): 2389-2392. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/15131
dc.description.abstract Investigation of the cytotoxic fraction of the extracts of the Red Sea sponge Suberea sp. resulted in the identification of two new compounds, 1-(hydroxy(1H-pyrrol-2-yl)methyl)guanidine and 4-(2-amino-3-methylbut-3-en-1-yl)phenol (1 and 2) together with the previously reported 2-(3,5-dibromo-4-hydroxyphenyl)acetamide (3), subereaphenol C (4), dibromoverongiaquinol (5) and bromochloroverongiaquinol (6). The compounds were assigned by interpretation of their one- and two-dimensional NMR and MS spectral data. The cytotoxic activities of the compounds against two cancer cell lines were evaluated. In addition, the antimicrobial activities of the compounds were discussed. en_US
dc.language.iso en en_US
dc.publisher Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi en_US
dc.subject Red Sea sponge en_US
dc.subject Suberea species en_US
dc.subject pyrrole derivatives en_US
dc.subject phenolic and halogenated compounds en_US
dc.subject cytotoxic and antimicrobial activities. en_US
dc.title Biologically active compounds from the red sea sponge Suberea sp. en_US
dc.type Article en_US


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