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In vitro activity of antimicrobial agents against streptococcus pyogenes isolated from different regions of Khyber Pakhtun Khwa Pakistan

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dc.contributor.author Rizwan, Muhammad
dc.contributor.author Bakht, Jehan
dc.contributor.author Bacha, Nafees
dc.contributor.author Ahmad, Bashir
dc.date.accessioned 2022-12-15T06:15:55Z
dc.date.available 2022-12-15T06:15:55Z
dc.date.issued 2016-01-20
dc.identifier.citation Rizwan, M., Bakht, J., Bacha, N., & Ahmad, B. (2016). In vitro activity of antimicrobial agents against streptococcus pyogenes isolated from different regions of Khyber Pakhtun Khwa Pakistan. Pakistan journal of pharmaceutical sciences, 29(1). en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/15152
dc.description.abstract The present study investigates the antibiotic resistance of S. pyogenes of 600 isolates collected from different body parts including throat and sputum were analyzed for their antimicrobial susceptibility to 5 antibiotics using the Kirby Bauer disc diffusion method. Based on different identification tests including, gram staining, beta hemolysis, catalase test and bacitracin sensitivity test, a total of 138 isolates were confirmed as S. pyogenes. The prevalence of S. pyogenes was 80% in sore throat and 29% in sputum samples. These isolates were further tested for antibiotics resistance using disk diffusion method. Out of 138 isolates, 49.27% isolates showed resistance towards cefixime, 28.98% towards cefotaxime and 17.39% towards ciprofloxacin, 17.39% towards ampicillin, 17.39% towards erythromycin, 15.94% towards streptomycin, 0.724% isolates towards chloromphenicol and 0% towards penicillin. Among the resistant isolates of S. pyogenes, 60.71% showed resistance towards cefixime, 57.14% towards ciprofloxacin, 57.14% towards streptomycin, 50% towards erythromycin and 25% towards cefotaxime en_US
dc.language.iso en en_US
dc.publisher Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi. en_US
dc.subject S. pyogenes. en_US
dc.subject Hemolysis en_US
dc.subject GAS, rheumatic fever en_US
dc.subject pharyngitis en_US
dc.subject Pyrrolidonyl arylmidase (PYR) en_US
dc.title In vitro activity of antimicrobial agents against streptococcus pyogenes isolated from different regions of Khyber Pakhtun Khwa Pakistan en_US
dc.type Article en_US


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