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A novel β-lactam derivative, albactam from the flowers of Albizia lebbeck with platelets anti-aggregatory activity in vitro
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| dc.contributor.author | Gamal, Ali Ali El | |
| dc.contributor.author | El Halim, Mohamed Farag Abd | |
| dc.contributor.author | Kalil, Ashraf Taha | |
| dc.contributor.author | Basudan, Omer Ahmed | |
| dc.contributor.author | Al-Rehaily, Adnan Jathlan | |
| dc.contributor.author | Ahmad, Mohamed Shamim | |
| dc.contributor.author | El Tahir, Kamal Hussin | |
| dc.contributor.author | Al-Massarani, Shaza Mohamed | |
| dc.contributor.author | Abdel-Mageed, Wael Moustafa | |
| dc.date.accessioned | 2022-12-15T06:25:48Z | |
| dc.date.available | 2022-12-15T06:25:48Z | |
| dc.date.issued | 2015-03-15 | |
| dc.identifier.citation | El Gamal, A. A., Abd El Halim, M. F., Kalil, A. T., Basudan, O. A., Al-Rehaily, A. J., Ahmad, M. S., ... & Abdel-Mageed, W. M. (2015). A novel β-lactam derivative, albactam from the flowers of Albizia lebbeck with platelets anti-aggregatory activity in vitro. Pak. J. Pharm. Sci, 28(2), 745-753. | en_US |
| dc.identifier.issn | 1011-601X | |
| dc.identifier.uri | http://142.54.178.187:9060/xmlui/handle/123456789/15165 | |
| dc.description.abstract | A novel β-lactam derivative, albactam, was isolated from the alcoholic extract of the flowers of Albizia lebbeck. It showed a significant anti-aggregatory activity against adenosine diphosphate and arachidonic acid induced guinea-pigs’ platelets aggregation in vitro. Six more known compounds were also isolated and fully characterized by measuring 1D and 2D NMR, two of them are the triterpenes β- amyrin and 11α, 12α-oxidotaraxerol, two ceramide derivatives and two flavonoids, kampferol 3-O-rutinoside and rutin. | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi | en_US |
| dc.subject | Albactam | en_US |
| dc.subject | Albizia lebbeck | en_US |
| dc.subject | flavonoids | en_US |
| dc.subject | platellete nti-aggregatory effect | en_US |
| dc.subject | triterpenes | en_US |
| dc.title | A novel β-lactam derivative, albactam from the flowers of Albizia lebbeck with platelets anti-aggregatory activity in vitro | en_US |
| dc.type | Article | en_US |
