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Antioxidant study of flavonoid derivatives from the aerial parts of Rhus natalensis growing in Saudi Arabia

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dc.contributor.author Alqasoumi, Saleh Ibrahim
dc.contributor.author Basudan, Omer Ahmed
dc.contributor.author Alam, Prawez
dc.contributor.author Abdel-Kader, Maged Saad
dc.date.accessioned 2022-12-15T06:27:19Z
dc.date.available 2022-12-15T06:27:19Z
dc.date.issued 2016-01-20
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/15168
dc.description.abstract Phytochemical study of the CH2Cl2 soluble fraction of the aerial parts of R. natalensis resulted in the isolation and identification of six flavonoid derivatives, β-amyrin and β-sitosterol glucoside (daucosterol). The isolated compounds were identified utilizing physical, chemical and different spectral methods including UV, 1D- 2D-NMR and MS. The compounds were identified as four flavanones; 7-O-methyl hesperetin (1), 7-O-methyl naringenin (4), (-)homoeriodictyol (eriodictyonone) (5), eriodictyol-7-methyl ether (6) and two flavones; 7-O-methyl isokaemferide (2) and genkwanin (3). The isolated compounds as well as some available standards representing structurally similar flavones and flavanones were used to study their antioxidant potential using DPPH and try to explore the impact of structures on the antioxidant activity. In other assays flavanones were less active than flavones as antioxidant due to lack of the C-4 carbonyl group in conjugation with 2,3-double bond. However, in DPPH assay based on the ability of molecules to donate hydrogen flavanones were found more active than flavones. en_US
dc.language.iso en en_US
dc.publisher Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi. en_US
dc.subject Rhus natalensis en_US
dc.subject flavanones; flavones en_US
dc.subject DPPH; antioxidant en_US
dc.title Antioxidant study of flavonoid derivatives from the aerial parts of Rhus natalensis growing in Saudi Arabia en_US
dc.type Article en_US


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