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In vitro antimicrobial activities of different solvent extracted samples from Iris germinica

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dc.contributor.author Uzair, Amjed
dc.contributor.author Bakht, Jehan
dc.contributor.author Iqbal, Arshad
dc.contributor.author Naveed, Khalid
dc.contributor.author Ali, Naushad
dc.date.accessioned 2022-12-15T06:50:24Z
dc.date.available 2022-12-15T06:50:24Z
dc.date.issued 2016-01-20
dc.identifier.citation Uzair, A., Bakht, J., Iqbal, A., Naveed, K., & Ali, N. (2016). In vitro antimicrobial activities of different solvent extracted samples from Iris germinica. Pakistan Journal of Pharmaceutical Sciences, 29(1). en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/15183
dc.description.abstract : Antibacterial and antifungal activities of different solvents extracted samples of Iris germinica were carried out through disc diffusion assay. For this purpose five different solvent extracts were prepared with two concentrations (1 and 2 mg disc-1) and their antimicrobial activity was tested using disc diffusion assay against eight pathogenic bacteria viz. Staphylococcus aureus, B. subtilis, Bacillus atrophaeus, Escherichia coli, Pseudomonas aeruginosa, Erwinia carotovara, Klebsiella pneumoniae, Salmonella typhi and one fungal specie (Candida albicans). Butanol and ethyl acetate fraction were more effective to control the growth of different pathogens followed by chloroform, hexane and aqueous fractions respectively. C. albicans, S. aureus E. carotovara, B. atrophaeus and E. coli were comparatively susceptible inhibited by all extracts of I. germinica compared with the rest of microbes. Maximum activity was shown by ethyl acetate extracted samples against B. atrophaeus followed by the same solvent against E. carotovara. Butanol extracted samples were effective against B. subtilis showing 62% reduction in growth at 1 or 2mg disc-1 concentration. From these results it can be concluded that different solvent extracted samples from the leaves of I. germinica possess varying degree of antimicrobial against different micro-organisms and can be a good sources of antibiotics for the treatment of certain bacterial and fungal diseases. en_US
dc.language.iso en en_US
dc.publisher Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi. en_US
dc.subject Iris germinica en_US
dc.subject antibacterial activity en_US
dc.subject antifungal activity en_US
dc.subject disc diffusion assay en_US
dc.title In vitro antimicrobial activities of different solvent extracted samples from Iris germinica en_US
dc.type Article en_US


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