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Development of cetyl dimethicone based water-in-oil emulsion containing botanicals: Physical characteristics and stability

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dc.contributor.author Waqas, Muhammad Khurram
dc.contributor.author Akhtar, Naveed
dc.contributor.author Akhtar Shah, Pervaiz
dc.contributor.author Zeeshan, Muhammad
dc.contributor.author Ali Shah, Arshad
dc.contributor.author Braga, Valdir de Andrade
dc.contributor.author Ali Khan, Barkat
dc.date.accessioned 2022-12-15T06:52:39Z
dc.date.available 2022-12-15T06:52:39Z
dc.date.issued 2016-01-20
dc.identifier.citation Waqas, M. K., Akhtar, N., Shah, P. A., Danish, M. Z., Shah, A. A., de Andrade Braga, V., & Khan, B. A. (2016). Development of cetyl dimethicone based water-in-oil emulsion containing botanicals: Physical characteristics and stability. Pakistan Journal of Pharmaceutical Sciences, 29(1). en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/15187
dc.description.abstract The aim of current research was to develop a water-in-oil emulsion containing grape seed extract for application in cosmeceuticals. Finally grinded dried grape seeds powder was extracted with hydro alcoholic mixture. Emulsions consisting of different concentrations of cetyl dimethicone (Abile EM90), the nonionic emulsifier, liquid paraffin as oily phase and water as aqueous phase were developed. Color, odor, pH, viscosity, liquefaction, phase separation, centrifugation and thermal stability of the formulated emulsions were observed at various storage temperatures i.e. 8±0.5°C, 25±0.5°C, 40±0.5°C and 40°C±0.5°C with 70% RH. The stable formulation consist of 16% mineral oil, 4% of ABIL EM 90®, 4% grape seeds extract, 1% rose oil and 75% distilled water. All the results derived from this study showed good stability over the three months study period which indicates w/o emulsion can be used as carrier of 4% grape seeds extract to enhance desired effects when applied topically. en_US
dc.language.iso en en_US
dc.publisher Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi. en_US
dc.subject Grape seed extract en_US
dc.subject w/o Emulsion, stability en_US
dc.subject pH, electrical conductivity en_US
dc.subject rheology en_US
dc.title Development of cetyl dimethicone based water-in-oil emulsion containing botanicals: Physical characteristics and stability en_US
dc.type Article en_US


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