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Efficacy of combination herbal product (Curcuma longa and Eugenia jambolana) used for diabetes mellitus

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dc.contributor.author Rao, Sadia Saleem
dc.contributor.author Najam, Rahila
dc.date.accessioned 2022-12-15T07:02:46Z
dc.date.available 2022-12-15T07:02:46Z
dc.date.issued 2016-01-20
dc.identifier.citation Rao, S. S., & Najam, R. (2016). Efficacy of combination herbal product (Curcuma longa and Eugenia jambolana) used for diabetes mellitus. Pakistan Journal of Pharmaceutical Sciences, 29(1). en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/15191
dc.description.abstract The purpose of this research was to evaluate the efficacy of a combination herbal product that is traditionally used for managing diabetes mellitus. Herbal drug contains Curcuma longa and Eugenia jambolana in the ratio of 1:1. It was orally administered at the dose of 1082 mg/70 kg twice a day for a period of 6 weeks to alloxan induced diabetic rats and compared with glibenclamide (standard). The effects of drug were observed at intervals, with respect to random and fasting glucose levels. HbA1C was also monitored after the drug treatment to monitor the overall diabetic effect. Results revealed that the combination of two herbs significantly reduced fasting and random glucose levels with HbA1C of less than 6% (p<0.001) in comparison to diabetic control. The control of fasting blood glucose levels by herbal combination is similar to the standard drug, glibenclamide (p<0.05). Random glucose levels by herbal combination is better than standard drug after one week and six weeks of treatment (p<0.01 and p<0.001 respectively) and similar after third week of treatment (p<0.05). Also, herbal drug combination showed HbA1C closer to the standard drug. It shows that this herbal combination can be of potential benefit in managing diabetes mellitus in future. en_US
dc.language.iso en en_US
dc.publisher Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi. en_US
dc.subject Curcuma longa en_US
dc.subject Eugenia jambolana en_US
dc.subject Alloxan en_US
dc.subject , Glibenclamide. en_US
dc.title Efficacy of combination herbal product (Curcuma longa and Eugenia jambolana) used for diabetes mellitus en_US
dc.type Article en_US


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