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Evaluation of antioxidant and antimicrobial activities of Bergenia ciliata Sternb (Rhizome) crude extract and fractions

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dc.contributor.author Khan, Aman
dc.contributor.author Jan, Gul
dc.contributor.author Danish, Muhammad
dc.date.accessioned 2022-12-16T10:14:54Z
dc.date.available 2022-12-16T10:14:54Z
dc.date.issued 2018-01-20
dc.identifier.citation Khan, A., Jan, G., Khan, A., Gul Jan, F., & Danish, M. (2018). Evaluation of antioxidant and antimicrobial activities of Bergenia ciliata Sternb (Rhizome) crude extract and fractions. Pakistan Journal of Pharmaceutical Sciences, 31(1). en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/15242
dc.description.abstract Biologically, screening of medicinal plants extracts have been since pre-historic to determine the antioxidants and antimicrobial profile. The present study was aimed to investigate and evaluate crude extract and different fractions of Bergenia ciliata Sternb (rhizome) for bioactivity which is most considerable medicinal plants. The chloroform fraction was found to be highly anti-oxidative with the IC50 value (4.15±0.82) as compare to ethyl acetate and n-hexane fraction. In addition, neither crude extract nor any fraction showed inhibition against fungal strains, i.e. Aspergillus flavus and Aspergillus niger. Furthermore, the crude extract and fractions of B. ciliata (rhizome) exhibiting promising activities against Bacillus atrophoeus, Bacillus subtilis, Kleibsiella pneumonia and Pseudomonas aeruginosa strains. In summary, B. ciliata is recommended as a source of bioactive compounds which might be used against oxidative stress and drug resistance bacteria. en_US
dc.language.iso en en_US
dc.publisher Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi. en_US
dc.subject Bergenia ciliata en_US
dc.subject antioxidant en_US
dc.subject antifungal en_US
dc.subject antibacterial en_US
dc.title Evaluation of antioxidant and antimicrobial activities of Bergenia ciliata Sternb (Rhizome) crude extract and fractions en_US
dc.type Article en_US


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