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GC-MS and HPLC profiles of phenolic fractions of the leaf of Telfairia occidentalis

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dc.contributor.author A Eseyin, Olorunfemi
dc.contributor.author A Sattar, Munavvar
dc.contributor.author A Rathore, Hassaan
dc.contributor.author Aigbe, Flora
dc.contributor.author Afzal, Sheryar
dc.contributor.author Ahmad, Ashfaq
dc.contributor.author Lazhari, Muhammad
dc.contributor.author Akthar, Safia
dc.date.accessioned 2022-12-19T04:48:00Z
dc.date.available 2022-12-19T04:48:00Z
dc.date.issued 2018-01-20
dc.identifier.citation Eseyin, O. A., Sattar, M. A., Rathore, H. A., Aigbe, F., Afzal, S., Ahmad, A., ... & Akthar, S. (2018). GC-MS and HPLC profiles of phenolic fractions of the leaf of Telfairia occidentalis. Pakistan journal of pharmaceutical sciences, 31(1). en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/15244
dc.description.abstract Telfairia occidentalis possesses high antioxidant activity. However, the antioxidant components of the plant have not yet been identified. This study was undertaken to identify the phenolics in the leaf of the plant. Extract and fractions of the leaf of the plant were analysed using the HPLC and GCMS. HPLC analysis revealed the presence of gallic acid (22.19µg/mg), catechin (29.17µg/mg), caffeic acid (9.17µg/mg), ferulic acid (0.94µg/mg), sinapic acid (1.91 µg/mg) and 4-hydroxy benzoic acid (43.86 µg/mg) in the aqueous extract. Phenolics fraction contained gallic acid (0.88 µg/mg), catechin (2.70µg/mg), caffeic acid (7.92µg/mg), ferulic acid (2.72µg/mg), benzoic acid (6.36µg/mg), pcoumaric acid (1.48µg/mg), quercetin (12.00µg/mg). Only caffeic acid (2.50µg/mg), ferulic acid (0.44µg/mg) and quercetin (8.50µg/mg) were detected in the flavonoid fraction. While GCMS analysis showed the presence of methylparaben; ethylparaben; benzoic acid; 4-hydroxy-2-methoxy-3,5,6-trimethyl-, methyl ester; 4-hydroxy-3-methoxy; phenol, 5-methoxy-2-(methoxymethyl)-; phenol, 5-methoxy-2, 3- dimethyl; and phenol, 2-(2-benzothiazolyl)-. This study is the first to reveal the identity of some phenolics components of the leaf of Telfairia occidentalis. en_US
dc.language.iso en en_US
dc.publisher Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi. en_US
dc.subject Fluted pumpkin en_US
dc.subject phenolics en_US
dc.subject antioxidant components en_US
dc.subject HPLC, GCMS en_US
dc.title GC-MS and HPLC profiles of phenolic fractions of the leaf of Telfairia occidentalis en_US
dc.type Article en_US


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