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Phytochemical screening and antibacterial activity of Cyclamen persicum Mill tuber extracts

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dc.contributor.author Raed Alkowni, Shehdeh Jodeh
dc.contributor.author Fatima Hussein, Nidal Jaradat
dc.date.accessioned 2022-12-19T09:58:00Z
dc.date.available 2022-12-19T09:58:00Z
dc.date.issued 2018-01-20
dc.identifier.citation Alkowni, R., Jodeh, S., Hussein, F., & Jaradat, N. (2018). Phytochemical screening and antibacterial activity of Cyclamen persicum Mill tuber extracts. Pakistan Journal of Pharmaceutical Sciences, 31(1). en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/15279
dc.description.abstract The emerging drug resistance bacteria increased the demand on the discovery of antibiotics from natural sources. This research was aimed to study the antibacterial reactivity; as well as the phytochemicals, of the wild type of Cyclamen persicum, using nine different extraction methods where four solvents (Methanol, Ethanol, Hexane; and Water) were involved with varied extraction periods ranged from 2 up to 10 hours. The antibacterial activity of crude methanol extract (CME) was found as the best method of extraction, with particular emphasis on the method with prolonged extraction time of (10 hrs). The antibacterial activities of produced CME were determined by using agar diffusion method against two of gram-positive bacteria and two gram-negative ones. The CME treated Mueller-HintonAgar plates, were exhibited antibacterial effects against the gram-positive bacteria (Staphylococcus aureus and Bacillus subtilis) by showing of inhibition zone after overnight incubation, while nothing was noticed on those of gram negative ones (Pseudomonas aeruginosa and Escherichia coli). These results that proved the antibacterial activity of the Cyclamen persicum tubers were positively tested the Saponin glycosides from plant. In addition to that, methanol solvent could be the useful method for extractions of Cyclamen and can be used in any developing drugs against pathogenic gram positive bacteria. en_US
dc.language.iso en en_US
dc.publisher Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi. en_US
dc.subject Cyclamen persicum tuber crude extracts en_US
dc.subject antibacterial activity en_US
dc.subject methanolic extracts en_US
dc.subject Pharmacognosy. en_US
dc.title Phytochemical screening and antibacterial activity of Cyclamen persicum Mill tuber extracts en_US
dc.type Article en_US


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