Abstract:
The anti inflammatory activity of methnolic root extract of Cissus quadrangularis L. (CQ) and seed extract of
Lepedium sativum L. (LS) were studied in rats also in conjunction with using a mixture (CL) of CQ and LS. The
estimation of anti-inflammatory activity was conducted by measuring volumetrically with the help of plethysmometer, the mean increase in hind paw volume of rat. Standard drug like diclofenac sodium within the dose of a 100 mg/kg is used. The doses of 50, 100 and 200 mg/kg of both plant extracts individually as well as combination were given. 0.9% NaCI (saline) solution given to control group. All the doses administered orally. Results showed that at dose of 50mg/kg showed potent activity by LS(4.06±0.03) and CQ(4.16±0.03), as CL (3.96±0.03) showed moderate activity while dose 100 and 200 mg / kg showed moderate activity by LS from respective standard i.e. Diclofenac Sodium.
