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Dexibuprofen: Statistical assessment of drug release kinetics and investigative quality perspective

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dc.contributor.author Anas M Hanif
dc.contributor.author Ali Akbar Sial
dc.contributor.author Huma Ali
dc.contributor.author Farya Zafar
dc.contributor.author Mirza Tasawar Baig
dc.contributor.author Rabia Bushra
dc.contributor.author Khan, Maqsood Ahmed
dc.contributor.author Amber Nawab
dc.contributor.author Omer Mustapha
dc.contributor.author Shumaila Shafique
dc.date.accessioned 2023-01-10T07:43:32Z
dc.date.available 2023-01-10T07:43:32Z
dc.date.issued 2018-09-20
dc.identifier.citation Hanif, A. M., Sial, A. A., Ali, H., Zafar, F., Baig, M. T., Bushra, R., ... & Shafique, S. (2018). Dexibuprofen: Statistical assessment of drug release kinetics and investigative quality perspective. Pakistan journal of pharmaceutical sciences. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/15931
dc.description.abstract Healthcare professionals including physicians and pharmacists have been trying since long to come across and work out regarding the issue of generic alternatives, which is highly affected by factors like therapeutic efficacy, cost effectiveness, aesthetic and elegant appearance and implementation of packaging number over the drug product. However, the community pharmacist professionals are also facing difficulty in making decision regarding selection and dispensing the most efficacious brand to the patients. In this regard, the initiation of recent approaches for the development of amenable drug products has led to evolve the concept of generating new avenues for achieving higher patient compliance. Hence, the objective of this study was to evaluate the quality attributes and make comparisons regarding different brands of Dexibuprofen available in market of Karachi, Pakistan. The study is based on evaluation of physical chemical parameters of five different brands. Moreover, a comparative dissolution profile of selected brands of Dexibuprofen was also performed by applying numerous approaches. DEX-1was selected as reference while DEX-2- DEX-5was selected as test brands. Results of all the selected brands met all the compendial requirements. Interpretation of the entire aforementioned test was evaluated using model independent, model- dependent and one – way ANOVA. The work presented in this study has been designed to provide quality standard products easily accessible in Pakistani market. en_US
dc.language.iso en en_US
dc.publisher Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi en_US
dc.subject Dexibuprofen en_US
dc.subject Physicochemical en_US
dc.subject Similarity en_US
dc.subject Quality en_US
dc.subject Pakistan en_US
dc.subject Brands en_US
dc.title Dexibuprofen: Statistical assessment of drug release kinetics and investigative quality perspective en_US
dc.type Article en_US


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