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Clinical efficacy of cryotherapy combined with interferon in the treatment of chronic cervicitis complicated with HPV infection

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dc.contributor.author Su, Yuehui
dc.contributor.author Zhang, Mengzhen
dc.contributor.author Zhang, Weiwei
dc.contributor.author Shi, Huirong
dc.date.accessioned 2023-01-10T08:05:05Z
dc.date.available 2023-01-10T08:05:05Z
dc.date.issued 2017-07-18
dc.identifier.citation Su, Y., Zhang, M., Zhang, W., & Shi, H. (2017). Clinical efficacy of cryotherapy combined with interferon in the treatment of chronic cervicitis complicated with HPV infection. Pakistan journal of pharmaceutical sciences, 30. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/15963
dc.description.abstract This paper aims to investigate the clinical curative effect and adverse reactions of cryotherapy combined with interferon in the treatment of chronic cervicitis complicated with HPV infection. 100 cases diagnosed with chronic cervicitis complicated with HPV infection from August 2014 to August 2015 in our hospital were selected and randomly divided into observation group (50 cases) and control group (50 cases). The preoperative and postoperative HPV-DNA changes were observed, and the vaginal discharge, time of decrustation and hemostasis, HPV negative conversion ratio and clinical efficacy were compared, to record the adverse reactions during treatment. After treatment, the level of RLU/CO value of the observation group was significantly lower than that of the control group (P<0.05); the vaginal discharge and time of decrustation and hemostasis of the observation group were shorter than that of the control group (P<0.05); 3 months after treatment, the HPV negative conversion ratio in the observation group was significantly higher than that in the control group; the total efficiency of the observation group was higher than that of the control group, with statistical significance (P<0.05). There were no serious adverse reactions in the two groups during the treatment. The efficiency of cervicitis complicated with HPV infection in the treatment of cryotherapy combined with interferon was more significantly. It can effectively reduce the load of HPV, promote the recovery of patients with pathological changes. Therefore, it is worth promoting. en_US
dc.language.iso en en_US
dc.publisher Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi en_US
dc.subject Chronic cervicitis en_US
dc.subject human papilloma virus en_US
dc.subject interferon en_US
dc.subject cryotherapy en_US
dc.title Clinical efficacy of cryotherapy combined with interferon in the treatment of chronic cervicitis complicated with HPV infection en_US
dc.type Article en_US


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