dc.contributor.author |
Qureshi, Muhammad Nasimullah |
|
dc.contributor.author |
Numonov, Sodik |
|
dc.contributor.author |
Haji Akber Aisa |
|
dc.date.accessioned |
2023-01-11T03:29:30Z |
|
dc.date.available |
2023-01-11T03:29:30Z |
|
dc.date.issued |
2019-07-02 |
|
dc.identifier.citation |
Qureshi, M. N., Numonov, S., & Aisa, H. A. (2019). Total polyphenolic compounds, total flavonoids, GC-MS analysis of volatile constituents, evaluation of antioxidant and antimicrobial activities of Prunus dulcis nuts. Pakistan Journal of Pharmaceutical Sciences, 32(4), 1461-1466. |
en_US |
dc.identifier.issn |
1011-601X |
|
dc.identifier.uri |
http://142.54.178.187:9060/xmlui/handle/123456789/15991 |
|
dc.description.abstract |
Prunus dulcis has been known as a source of nutrients in many traditional foods and as a source of important
biologically active compounds in traditional medicines. The present study describes the determination of total
polyphenolic compounds, total flavonoids and GC-MS analysis of hexane and chloroform fractions of 70% ethanol extract of whole almond shelled seed. Antioxidant and antimicrobial activities of various extracts of the nuts were evaluated. Folin-Ciocalteau procedure resulted in total polyphenolic compounds as 0.008 mg (gallic acid equivalents)/mg of the dried extract and amount of total flavonoids contents yielded were 0.001 mg (quercetin equivalents)/mg of the nuts dried extracts. GC-MS analysis of the hexane and chloroform fractions yielded a number of volatile constituents, resulting in highest amounts of 6-Octadecenoic acid and 1,1,3,3-Tetramethyl cyclopentane as 37.52% and 24.54% in hexane and chloroform fractions respectively. Antioxidant activity using the DPPH radical scavenging assay resulted in very low activity in all the extracts. Only n-butanol extract showed mild activity against the gram negative E. coli with inhibition zone diameter 8 mm while rest of samples did not show any activity against any microbial strains under study. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi |
en_US |
dc.subject |
Prunus dulcis nuts |
en_US |
dc.subject |
total polyphenolics and flavonoids contents |
en_US |
dc.subject |
GC-MS |
en_US |
dc.subject |
antioxidant activity |
en_US |
dc.subject |
antimicrobial activity |
en_US |
dc.title |
Total polyphenolic compounds, total flavonoids, GC-MS analysis of volatile constituents, evaluation of antioxidant and antimicrobial activities of Prunus dulcis nuts |
en_US |
dc.type |
Article |
en_US |