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Investigation of the effects of Achillea millefolium extract in diabetic rats with second-degree Burns

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dc.contributor.author Allahverdi, Tulay Diken
dc.contributor.author Allahverdi, Ertugrul
dc.contributor.author Kilicle, Pınar Aksu
dc.contributor.author Ozen, Hasan
dc.date.accessioned 2023-01-19T04:06:53Z
dc.date.available 2023-01-19T04:06:53Z
dc.date.issued 2018-05-01
dc.identifier.citation Allahverdi, T. D., Allahverdi, E., Kilicle, P. A., & Ozen, H. (2018). Investigation of the effects of Achillea millefolium extract in diabetic rats with second-degree Burns. Pakistan Journal of Pharmaceutical Sciences, 31. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/16062
dc.description.abstract Our aim was to investigate the effects of Achillea millefolium on wound healing in second-degree burns formed in diabetic rats. This study was conducted at the Kafkas University Experimental Research Center. 20 Sprague Dawley rats were divided into 2 groups. Group I (n=10 rats) was the Control group and contained the diabetic rats with burn injury. Group II (n=10 rats) was the group where burn injury was created and Achillea millefolium was administered to diabetic rats. The backs of the rats were shaved so as to include 30% of the body area. A 10% lanolin extract was administered for 14 days after the burn injury was created. Tissue was obtained from the burn area of the rats sacrificed. No significant difference was found in Group II in terms of the severity of the dermatitis and inflammatory cell reactions when compared to Group I. No significant difference was observed between FGFR1immunoreactivity in the epidermis and dermis in Group I. While FGFR1immunoreactivity in 3 rats in Group II was similar to Group I, strong immunore activity that was more prominent in the epidermis was found in 7 rats in Group II. We believe that Achillea millefolium contributes to wound healing in burn injury due to its antioxidant and anti-inflammatory properties. en_US
dc.language.iso en en_US
dc.publisher Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi en_US
dc.subject Achillea millefolium en_US
dc.subject burn en_US
dc.subject diabetes en_US
dc.subject antioxidant en_US
dc.title Investigation of the effects of Achillea millefolium extract in diabetic rats with second-degree Burns en_US
dc.type Article en_US


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