dc.contributor.author |
Sari, Ika Puspita |
|
dc.contributor.author |
Nurrochmad, Arief |
|
dc.contributor.author |
Setiawan, Irfan Muris |
|
dc.contributor.author |
Hertiani, Triana |
|
dc.contributor.author |
Paramita, Annisa Dian |
|
dc.contributor.author |
Annisa, Anggit Yustitia |
|
dc.date.accessioned |
2023-01-19T04:25:43Z |
|
dc.date.available |
2023-01-19T04:25:43Z |
|
dc.date.issued |
2018-05-05 |
|
dc.identifier.citation |
Sari, I. P., Nurrochmad, A., Setiawan, I. M., Hertiani, T., Paramita, A. D., & Annisa, A. Y. (2018). Effects of Costus speciosus ethanolic extract on male rats: The action mechanism and the ability to impregnate. Pakistan Journal of Pharmaceutical Sciences, 31. |
en_US |
dc.identifier.issn |
1011-601X |
|
dc.identifier.uri |
http://142.54.178.187:9060/xmlui/handle/123456789/16066 |
|
dc.description.abstract |
To examine the action mechanism that mediates the anti-fertility effect of Costus speciosus extract, research
was conducted on male Sprague-Dawley rats. Costus extract was given to male rats for 14 days at various doses, namely 275, 550 and 1,100 mg kg-1 day-1 in 0.5% sodium CMC. The results showed that Costus extract with doses ranging from 275 to 1,100 mg kg-1 day-1 was able to inhibit pregnancy among female rats by 10-70%. No obstacles in terms of sexual behavior were identified among male rats. The anti-fertility effect of Costus extract kicked in without involving a decreased level of male reproductive hormones. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi |
en_US |
dc.subject |
Costus extract |
en_US |
dc.subject |
reproductive hormones |
en_US |
dc.subject |
obstacles to pregnancy |
en_US |
dc.subject |
sexual behavior |
en_US |
dc.title |
Effects of Costus speciosus ethanolic extract on male rats: The action mechanism and the ability to impregnate |
en_US |
dc.type |
Article |
en_US |