dc.contributor.author |
Muhammad Baseer |
|
dc.contributor.author |
Ansari, Farzana Latif |
|
dc.contributor.author |
Zaman Ashraf |
|
dc.date.accessioned |
2023-01-19T05:33:38Z |
|
dc.date.available |
2023-01-19T05:33:38Z |
|
dc.date.issued |
2017-07-20 |
|
dc.identifier.citation |
Baseer, M., Ansari, F. L., & Ashraf, Z. (2013). Synthesis, in vitro antibacterial and antifungal activity of some n-acetylated and non-acetylated pyrazolines. Pak. J. Pharm. Sci, 26(1), 67-73. |
en_US |
dc.identifier.issn |
1011-601X |
|
dc.identifier.uri |
http://142.54.178.187:9060/xmlui/handle/123456789/16088 |
|
dc.description.abstract |
Fourteen new N-acetylated and non-acetylated pyrazoline derivatives were synthesized by reacting chalcones with hydrazine in the presence of absolute ethanol however reaction was carried out in the presence of glacial acetic acid to afford N-acetylated pyrazolines. The chemical structures of the synthesized pyrazolines were confirmed by FTIR, 1HNMR, 13CNMR and mass spectroscopic data. The pyrazolines (1-14) were screened for antibacterial activity against ten bacterial strains using seven Gram-positive and three Gram-negative bacteria and antifungal activity against Aspergillus Flavus, Aspergillus Niger and Aspergillus pterus. Pyrazolines (1-14) found to exhibit good to excellent antimicrobial activities compared to the Levofloxacin and fluconazole used as standard drugs. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
Karachi: Pakistan Botanical Society, University of Karachi |
en_US |
dc.subject |
Pyrazolines |
en_US |
dc.subject |
antibacterial activity |
en_US |
dc.subject |
antifungal activity. |
en_US |
dc.title |
Synthesis, in vitro antibacterial and antifungal activity of some n-acetylated and non-acetylated pyrazolines |
en_US |
dc.type |
Article |
en_US |