PASTIC Dspace Repository

Synthesis, in vitro antibacterial and antifungal activity of some n-acetylated and non-acetylated pyrazolines

Show simple item record

dc.contributor.author Muhammad Baseer
dc.contributor.author Ansari, Farzana Latif
dc.contributor.author Zaman Ashraf
dc.date.accessioned 2023-01-19T05:33:38Z
dc.date.available 2023-01-19T05:33:38Z
dc.date.issued 2017-07-20
dc.identifier.citation Baseer, M., Ansari, F. L., & Ashraf, Z. (2013). Synthesis, in vitro antibacterial and antifungal activity of some n-acetylated and non-acetylated pyrazolines. Pak. J. Pharm. Sci, 26(1), 67-73. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/16088
dc.description.abstract Fourteen new N-acetylated and non-acetylated pyrazoline derivatives were synthesized by reacting chalcones with hydrazine in the presence of absolute ethanol however reaction was carried out in the presence of glacial acetic acid to afford N-acetylated pyrazolines. The chemical structures of the synthesized pyrazolines were confirmed by FTIR, 1HNMR, 13CNMR and mass spectroscopic data. The pyrazolines (1-14) were screened for antibacterial activity against ten bacterial strains using seven Gram-positive and three Gram-negative bacteria and antifungal activity against Aspergillus Flavus, Aspergillus Niger and Aspergillus pterus. Pyrazolines (1-14) found to exhibit good to excellent antimicrobial activities compared to the Levofloxacin and fluconazole used as standard drugs. en_US
dc.language.iso en en_US
dc.publisher Karachi: Pakistan Botanical Society, University of Karachi en_US
dc.subject Pyrazolines en_US
dc.subject antibacterial activity en_US
dc.subject antifungal activity. en_US
dc.title Synthesis, in vitro antibacterial and antifungal activity of some n-acetylated and non-acetylated pyrazolines en_US
dc.type Article en_US


Files in this item

This item appears in the following Collection(s)

Show simple item record

Search DSpace


Advanced Search

Browse

My Account